Navigation Links
FDA Approves Label Update for PREZISTA® to Include 192-Week Data in HIV-1-Infected Adult Patients Starting Treatment
Date:10/21/2011

does not prevent passing HIV-1 to others.

Drug Interactions

  • Coadministration of PREZISTA/ritonavir is contraindicated with drugs that are highly dependent on CYP3A for clearance and for which elevated plasma concentrations are associated with serious and/or life-threatening events (e.g., alfuzosin, dihydroergotamine, ergonovine, ergotamine, methylergonovine, cisapride, pimozide, oral midazolam, triazolam, lovastatin, or simvastatin)
  • Coadministration of PREZISTA/ritonavir is also contraindicated with rifampin and products containing St. John's wort (Hypericum perforatum) because this may cause significant decrease in plasma concentration of darunavir, resulting in loss of therapeutic effect and development of resistance
  • Coadministration is not recommended with indinavir, lopinavir/ritonavir, saquinavir, and pravastatin
  • Caution should be used when prescribing agents such as sildenafil, vardenafil, tadalafil, or other substrates, inhibitors, or inducers of CYP3A in patients receiving PREZISTA/ritonavir.

  • This list of potential drug interactions is not complete.Warnings & Precautions

  • PREZISTA must be coadministered with ritonavir and food to achieve the desired antiviral effect. Failure to administer PREZISTA with ritonavir and food may result in a loss of efficacy of darunavir. Please refer to ritonavir prescribing information for additional information on precautionary measures
  • Drug-induced hepatitis (e.g., acute hepatitis, cytolytic hepatitis) has been reported with PREZISTA/ritonavir. During the clinical development program (N=3063), hepatitis has been reported in 0.5% of patients receiving combination therapy with PREZISTA/ritonavir. Patients with preexisting liver dysfunction, including chronic active hepatitis B or C, have an increased risk for liver function abnormalities, including severe hepatic adverse events

  • Post-marketing cases of liver in
    '/>"/>

    SOURCE Janssen Therapeutics, Division of Janssen Products, LP
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6

    Related medicine technology :

    1. FDA Approves Ferriprox to Treat Patients with Excess Iron in the Body
    2. FDA Approves Combination Therapy Juvisync
    3. FDA Approves Cialis to Treat Benign Prostatic Hyperplasia
    4. FDA Approves Remicade to Treat Ulcerative Colitis in Children Older Than 6 Years
    5. FDA Approves Soliris for Rare Pediatric Blood Disorder
    6. FDA Approves New Indications for Prolia® (Denosumab) for the Treatment of Bone Loss in Patients With Prostate or Breast Cancer Undergoing Hormone Ablation Therapy
    7. FDA Approves Xalkori with Companion Diagnostic for a Type of Late-stage Lung Cancer
    8. FDA Approves Firazyr To Treat Acute Attacks of Hereditary Angioedema
    9. FDA Approves Adcetris to Treat Two Types of Lymphoma
    10. FDA Approves the First Specific Treatment for Scorpion Stings
    11. Cardinal Health Board of Directors Approves Cash Dividend, Elects David P. King as Director
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:1/23/2015)... 2015  A new analysis of Centers for Medicare and ... shows that 81 percent of seniors chose lower-cost preferred ... at certain pharmacies. The findings were released by ... now the foundation of Medicare Part D," said Pharmaceutical ...
    (Date:1/23/2015)... 23, 2015 More than a third of reproductive-aged women ... with private insurance, filled a prescription for an opioid pain ... this week,s Morbidity and Mortality Weekly Report (MMWR). ... treat moderate to severe pain.  They are also found in ...
    (Date:1/23/2015)... Jan. 23, 2015  Pete Rose, baseball,s all-time hits leader, is ... pain reliever Myoflex, Ducere Pharma has announced. "Pete,s ... excited to have him on board with Myoflex," said Ducere ... a legendary player who is known across all generations. The ...
    Breaking Medicine Technology:New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2Opioid painkillers widely prescribed among reproductive age women 2Opioid painkillers widely prescribed among reproductive age women 3Pete Rose bets on Myoflex to relieve aches and pains 2
    (Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved television ... 32nd Annual Miami Breast Cancer Conference planned ... (PER®) , shares that “a fast-growing, virulent” cancer in ... had not followed up her clean mammogram with an ...
    (Date:1/22/2015)... has added many trendy Champagne wedding dresses to ... the past three years. Today, the business announces a special ... the sales manager of the company, this is on the ... point can be reflected on the discounted wedding dresses from ...
    (Date:1/22/2015)... WASHINGTON, DC (PRWEB) January 22, 2015 ... conditions in vulnerable communities and cause financial distress to ... report by analysts at Howard University’s Center on Race ... of dollars in economic activity, payday loans at the ...
    (Date:1/22/2015)... 2015 JJsHouse.com is a famous dress online ... business announces its latest collection of wedding dresses , ... important issue is the wedding dress on your big day; ... woman’s life. Every bride wants to find the most suitable ...
    (Date:1/22/2015)... Step into a macabre world where ... of Virginia. Wicked Plants, the Museum’s latest featured exhibition, ... poisonous, carnivorous and diabolical plants inside of a dilapidated, ... the biochemical, physical and neurological processes between botanicals and ...
    Breaking Medicine News(10 mins):Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2
    ... to Support In-depth, Explanatory Reporting , , ... uncertainty and transition in the news media, the University of ... partnership with the California HealthCare Foundation (CHCF) to undertake in-depth ... , Funded by a three-year $3,285,000 grant, ...
    ... , , , ... continue to deliver on its vision of a world without breast ... in-depth, county-wide research and community needs assessment to identify disparities in ... every two years to ensure its programs are meeting the breast ...
    ... ... , ... September 17, 2009 -- MRPC ( http://www.mrpcorp.com ), a leading single-source provider of innovative ... The certification covers all disciplines within the company. MRPC is also ISO 9001 certified., ...
    ... , LOS ANGELES, Sept. 17 United ... the one million dollar Mullin-Miller Match Fund. The fund, created by ... D. Miller, retired Chairman and CEO, Avery Dennison Corporation, will provide ... to the Creating Pathways Out of Poverty Plan, up to the ...
    ... , DALLAS, Sept. 17 Prostate cancer is the ... in six men being diagnosed with the disease in their lifetime. ... as a strong advocate for prostate cancer awareness, Kimberly-Clark and its ... End Prostate Cancer to help educate men on the risks associated ...
    ... important analysis conducted by Children,s Hospital Oakland Research Institute ... of vitamin K to prevent age-related conditions such as ... possibly cancer (1). Vitamin K is concentrated in dark ... is either not present or present in only small ...
    Cached Medicine News:Health News:USC Annenberg and California HealthCare Foundation Join in New Health Care Journalism Venture 2Health News:USC Annenberg and California HealthCare Foundation Join in New Health Care Journalism Venture 3Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 2Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 3Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 4Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 5Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 6Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 7Health News:Susan G. Komen for the Cure(R), San Diego Releases Community Profile Unveiling Alarming Statistics About Breast Cancer in San Diego County 8Health News:Medical Device Manufacturer MRPC Awarded ISO 13485 Certification 2Health News:United Way of Greater Los Angeles Announces Matching Fund Launched by Two Local Philanthropists 2Health News:Video: 'The Depend Campaign to End Prostate Cancer' Brings Sports Legends Together to Celebrate National Prostate Cancer Awareness Month 2Health News:New vitamin K analysis supports the triage theory 2
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
    ... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    Medicine Products: