Navigation Links
FDA Approves Ferriprox to Treat Patients with Excess Iron in the Body
Date:10/14/2011

SILVER SPRING, Md., Oct. 14, 2011 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration today approved Ferriprox (deferiprone) to treat patients with iron overload due to blood transfusions in patients with thalassemia, a genetic blood disorder that causes anemia, who had an inadequate response to prior chelation therapy.

(Logo: http://photos.prnewswire.com/prnh/20090824/FDALOGO)

Patients with thalassemia have excess iron in the body from the frequent blood transfusions (transfusional iron overload), a condition that is serious and can be fatal.  These patients also have a risk of developing liver disease, diabetes, arthritis, heart failure or an abnormal heart rhythm.  

The standard of care to treat transfusional iron overload is chelation therapy – chemical agents that are used to remove heavy metals from the body. Ferriprox is intended for use when chelation therapy is inadequate.

"Ferriprox represents the first new FDA-approved treatment for this disorder since 2005," said Richard Pazdur, M.D., director of the Office of Hematology and Oncology Products in the FDA's Center for Drug Evaluation and Research.

The safety and effectiveness of Ferriprox is based on an analysis of data from twelve clinical studies in 236 patients. Patients participating in the study did not respond to prior iron chelation therapy.  Ferriprox was considered a successful treatment for patients who experienced at least a 20 percent decrease in serum ferritin, a protein that stores iron in the body for later use. Half of the patients in the study experienced at least a 20 percent decrease in ferritin levels.

The most common side effects seen in patients who received Ferriprox included nausea, vomiting, abdominal and joint pain, urine discoloration (chromaturia), a decrease in the number of white blood cells (neutropenia), and an increase in
'/>"/>

SOURCE U.S. Food and Drug Administration
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
2. Health Canada Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/ tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for HIV
3. FDA Approves Cymbalta(R) for Maintenance Treatment of Major Depressive Disorder
4. European Commission Approves ATRIPLA(R) (efavirenz 600 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), the First Once-Daily Single Tablet Regimen for Virologically Suppressed Adults With HIV-1 Infection
5. FDA Approves MiddleBrooks Amoxicillin PULSYS for Pharyngitis/Tonsillitis in Adolescents and Adults
6. FDA Approves XYZAL(R) (levocetirizine dihydrochloride) Oral Solution for the Relief of Seasonal and Year Round Allergies and Chronic Idiopathic Urticaria
7. UM Maryland Industrial Partnerships Program Approves 18 Collaborative Research Projects, Worth $4.4 Million, Between University Faculty, State Technology Companies
8. U.S. Food and Drug Administration Approves ABILIFY(R) (aripiprazole) for the Acute Treatment of Manic and Mixed Episodes Associated With Bipolar I Disorder in Pediatric Patients (10 to 17 Years of Age)
9. U.S. Food and Drug Administration Approves ORENCIA(R) (abatacept) for the Treatment of Moderate-to-Severe Polyarticular Juvenile Idiopathic Arthritis (JIA) in Patients Six Years and Older
10. FDA Approves HIFU Clinical Trial for Recurrent Prostate Cancer
11. EPA Approves XDS-CALUX(R) as Alternate Dioxin Test Method 4435
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/15/2014)... , Dec. 12, 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/ms3j8c/cardiac ) has announced the addition of ... Forecasts, 2012-2018"  report to their offering. Global Guidewires ... The North America accounts for ... Europe claims approximately 25% (2018). ...
(Date:12/15/2014)... 2014  Colorado and Washington State ... of cannabis. Oregon , Alaska ... prohibition during the November 2014 elections. Photo ... The benefits of legalizing cannabis are ... like the increased tax revenue for state and local governments, ...
(Date:12/15/2014)... Government of Ghana has endorsed a project ... Terumo BCT to respond to the emerging Ebola crisis within ... system capacity to the citizens of Ghana . ... and Resilience Initiative (GERRI) is a multi-agency effort designed to: ... arrival of the Ebola epidemic , Provide new blood product ...
Breaking Medicine Technology:Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 2Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 3Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 4Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 5Government of Ghana Endorses Collaboration to Combat Ebola Epidemic 6
... ("Unilife" or the "Company") (NASDAQ: UNIS ; ... the fourth quarter and fiscal year ended June 30, ... Completed construction of new global headquarters and commercial production ... (December 2010) Appointed Dr. Ramin Mojdeh as Chief ...
... AUSTIN, Texas, Aug. 30, 2011 Luminex Corporation (Nasdaq: ... present at two upcoming investment conferences, the Morgan Stanley ... Conference, both scheduled to take place in New York ... Patrick J. Balthrop, president and chief executive ...
Cached Medicine Technology:Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 2Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 3Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 4Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 5Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 6Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 7Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 8Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 9Unilife Corporation Announces Preliminary Financial Results for the Fourth Quarter and Fiscal Year 2011 10Luminex Corporation to Present at Upcoming Investment Conferences In September 2
(Date:12/17/2014)... 2014 A group of 127 scientists sent ... in reaction to a recent statement by the center that ... and derogated the efficacy of all brain exercises. , Signatories ... parts of the center’s statement critical of brain exercise companies ... also overstated its case, in a document it had entitled ...
(Date:12/17/2014)... 2014 Project Veritas is releasing a ... of MIT economist and Obamacare architect Jonathan Gruber to ... conducted the interview, which is being distributed on YouTube. ... intentional mislabeling in the Affordable Care Act in order ... two-hundred-and-fifty billion dollar per year tax grab. , “President ...
(Date:12/17/2014)... students get more fruits and vegetables at school than they ... opposite is true for students from wealthier families. These ... give a healthy boost to poor students, diets, according to ... level, students all ate a similar amount of fruits and ... published recently in the journal Preventive Medicine . ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. ... in America, and work commitment is a big reason why, ... killer," said Dr. Mathias Basner, an assistant professor of sleep ... School of Medicine. A time-use survey of nearly 125,000 ... the main activity exchanged for sleep. Short sleepers -- those ...
(Date:12/15/2014)... Main Street Dental Team ( http://www.MainStreetDentalTeam.com ... on a new study providing evidence on the impact ... of children. , Sufficient enough evidence already exists showing ... or juice drinks, with the onset of tooth decay. ... drinks listed as 100% fruit juice, meaning it is ...
Breaking Medicine News(10 mins):Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 2Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 3Health News:Scientists to Stanford: Research Shows Brain Exercises Can Work 4Health News:Project Veritas: James O’Keefe Interviews the Man Who Discovered Jonathan Gruber Videos 2Health News:Poor Students Eat Healthier Foods at School, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:Main Street Dental Team, Unionville’s Most Innovative Dental Clinic, Comments on New Study Relating Pure Fruit Juice to Poor Oral Hygiene 2
... , , , ... this fall, U.S. public health officials and other leading medical experts ... protection against seasonal influenza - a threat to Americans, health each ... is already available in many communities and Americans should begin to ...
... September 2009 - Drug treatment options for depression can ... is clearly inadequate for those at immediate risk of ... used as an anesthetic, has shown rapid antidepressant effects ... effects on suicidality in patients with treatment-resistant depression, and ...
... , HAYWARD, Calif., Sept. 10 Solta ... the launch of the new Thermage CPT and Fraxel re:store Dual ... ( www.illumiNATIONtour.com ). Starting September 14 and continuing through ... and Fraxel(R) systems directly to physicians in over 20 cities across ...
... , HOUSTON, Sept. 10 Cyberonics, ... President and Chief Executive Officer, and Greg Browne, Chief Financial Officer, ... York on Tuesday, September 22, 2009 at 4:00 PM EDT. ... replay at http://cc.talkpoint.com/ubsx001/092109a_ke/?entity=82_IT8KY1C . The replay will ...
... LITTLE FALLS, N.J., Sept. 10 CANTEL MEDICAL ... A. Krakauer, President & CEO, will be presenting at the UBS ... AM ET on Tuesday, September 22, 2009 at the Grand Hyatt ... presentation. In addition, Mr. Krakauer and Seth R. Segel, Executive Vice ...
... resulted in roughly same outcome, research shows , ... workers with mental health problems return to near-normal productivity, ... mental stress seemed to have the same effect, researchers ... regarding mental health and productivity levels in more than ...
Cached Medicine News:Health News:Americans Urged To Get Seasonal Influenza Vaccine Early 2Health News:Americans Urged To Get Seasonal Influenza Vaccine Early 3Health News:Americans Urged To Get Seasonal Influenza Vaccine Early 4Health News:Americans Urged To Get Seasonal Influenza Vaccine Early 5Health News:Americans Urged To Get Seasonal Influenza Vaccine Early 6Health News:Solta Medical Launches illumiNATION tour in U.S. and Europe to Introduce New Thermage CPT(TM) and Fraxel re:store(R) Dual Systems 2Health News:Solta Medical Launches illumiNATION tour in U.S. and Europe to Introduce New Thermage CPT(TM) and Fraxel re:store(R) Dual Systems 3Health News:Cyberonics to Present at UBS Global Life Sciences Conference 2Health News:Treating Workers' Mental Woes May Boost Productivity 2
Inquire...
Inquire...
Nature's Remarkable Skin Protector -- Karaya 5 is a natural skin barrier that is particularly well suited for skin problems or for sensitive skin where reactions may have occurred to other types of s...
Superior Skin Care...FlexWear skin barrier provides skin protection for an extended wear time....
Medicine Products: