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FDA Approves Cymbalta® for the Management of Chronic Musculoskeletal Pain
Date:11/4/2010

eople with chronic musculoskeletal pain have different treatments available to them because responses to medications can be highly individualized," said Robert Baker, M.D., global development leader for psychiatry and pain disorders at Lilly. "This is why we are happy to be able to provide doctors and patients with a new option."

Osteoarthritis affects an estimated 27 million adults in the U.S.(i) An estimated 70 to 85 percent of adults experience low back pain at some time,(ii) with some reports estimating that 2 to 10 percent of these people go on to experience chronic low back pain.(iii) (iv) (v) (vi)  

"Having a medication that is approved specifically for people with chronic musculoskeletal pain is a great step in helping these individuals live with less chronic low back pain or chronic pain due to osteoarthritis. Good medical care from a health care professional and involvement by the person with the condition is important," said Penney Cowan, executive director, American Chronic Pain Association.

About Cymbalta

Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Although the exact way that Cymbalta works in people is unknown, it is believed to be related to an increase in the activity of serotonin and norepinephrine, two naturally occurring substances in the brain and spinal cord.

Cymbalta is approved in the United States for the treatment of major depressive disorder, the treatment of generalized anxiety disorder, the management of diabetic peripheral neuropathic pain, fibromyalgia and chronic musculoskeletal pain, which has been established in studies in patients with chronic low back pain and chronic pain due to osteoarthritis, all in adults (18+). Cymbalta is not approved for use in pediatric patients.

Indications and Important Safety Information About Cymbalta

Indications


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SOURCE Eli Lilly and Company
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