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FDA Approves Cymbalta(R) for Maintenance Treatment of Generalized Anxiety Disorder
Date:11/30/2009

, the management of diabetic peripheral neuropathic pain and fibromyalgia, and for the acute treatment of generalized anxiety disorder, all in adults.

Generalized anxiety disorder affects nearly 7 million Americans at any given time.(i) While the symptoms of GAD can vary from person to person, they may include excessive worry or anxiety over a period of six months or longer, difficulties controlling worry, irritability, poor concentration, sleep disturbances, fatigue, restlessness and muscle tension.(ii) If left untreated, symptoms may get progressively worse.(iii) Additionally, GAD can have a negative impact on a person's ability to function well in work, family and social situations.(iv)

About Cymbalta

Serotonin and norepinephrine in the brain and spinal cord are believed to both mediate core mood symptoms and help regulate the perception of pain. Based on preclinical studies, Cymbalta is a balanced and potent reuptake inhibitor of serotonin and norepinephrine that is believed to potentiate the activity of these chemicals in the central nervous system (brain and spinal cord). While the mechanism of action of Cymbalta is not known, scientists believe its effects on depression and anxiety symptoms, as well as its effect on pain perception, may be due to increasing the activity of serotonin and norepinephrine in the central nervous system.

Indications and Important Safety Information About Cymbalta

Indications

Cymbalta is approved to treat major depressive disorder and generalized anxiety disorder, and to manage diabetic peripheral neuropathic pain and fibromyalgia.

Important Safety Information About Cymbalta

Antidepressants can increase suicidal thoughts and behaviors in children, adolescents, and young adults. Suicide is a known risk of depression and some other psychiatric disorders. Patients should call their doctor right away if they experienc
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SOURCE Eli Lilly and Company
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