Navigation Links
FASgen Announces a New Discovery in Obesity Research
Date:12/21/2007

BALTIMORE, Dec. 21 /PRNewswire/ -- FASgen is pleased to report the publication of important new research results in the obesity field using FAS89B, one of the Company's proprietary compounds. FASgen is a leader in the field of research into selective inhibition of fatty acid synthase (FASi), and has conducted extensive research in the area of metabolic disease disorders, specifically for the treatment of obesity and fatty liver disease. The Company has a long-standing cooperation with The Johns Hopkins University, and that joint research has produced the new discoveries in the regulation of weight loss by the stimulation of carnitinepalmitoyl-transferase-1 (CPT-1). FAS89B was characterized in vitro as a selective inhibitor of brain CPT-1 and produced in vivo results in mice of decreased feeding for three days and persistent weight loss of six days, with no evidence of conditioned taste aversion. See, "Pharmacological Stimulation of Brain Carnitine-Transerase-1 Decreases Food Intake and Body Weight," Ronnett, et al, Am J Physiol Regul Integr Physiol (December 8, 2007). This new discovery adds another tool for FASgen to use, in addition to FASi and GPATi compounds already in research, in its ongoing program of research into the field of treatment for obesity and fatty liver disease.

About FASgen, Inc.: FASgen, Inc. is a drug development company founded in 2000 by four distinguished Johns Hopkins researchers to create new therapeutic products based on the selective inhibition of fatty acid biosynthesis. The Company has the exclusive license from Johns Hopkins to more than 15 years of research in the field, which research continues under a sponsored research agreement with the University.

The Company has designed and synthesized many compounds that selectively inhibit fatty acid biosynthesis. One group of these compounds holds great promise for new highly specific therapeutics for cancer; additional compounds have the potential of specific therapeutics for obesity and related metabolic disorders; and, an additional group of compounds have the potential of specific therapeutics for TB, including multiple drug resistant TB (MDR-TB) and latent TB infections that affect one third of the world's population. For more information, visit FASgen's website at http://www.fasgen.com.


'/>"/>
SOURCE FASgen, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Related medicine technology :

1. FASgen Announces Significant Milestone in Its Cancer Drug Development Program
2. FASgen Announces New Discovery for Treatment of Stroke
3. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
4. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
5. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
6. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
7. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
8. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
9. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
10. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
11. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/17/2018)... ... November 17, 2018 , ... Sublime front man Bradley Nowell eventually lost his ... family created the nonprofit 501(c)3, The Nowell Family Foundation . The Foundation provides ... industry and those who have been touched by the power of music. The foundation ...
(Date:11/16/2018)... ... November 16, 2018 , ... Privately operated aerial firefighting companies quickly went ... Northern and Southern California. The Camp Fire, in Butte County, and the Woolsey ... other during the first week of November. All are still mostly uncontained. , ...
(Date:11/16/2018)... ... November 16, 2018 , ... Design.ME haircare and styling ... quickly refreshes and restores hair between washes. , Designed to lift and ... products, including an instant drying foam that can be used on all hair ...
Breaking Medicine Technology:
(Date:11/16/2018)... , ... November 16, 2018 , ... ... Kurapati's latest book Physician: How Science Transformed the Art of Medicine (GreenLeaf Press, ... in nonfiction health and medical. , Interweaving moving personal patient stories with ...
(Date:11/16/2018)... N.D. (PRWEB) , ... November 16, 2018 , ... ... marijuana dispensary licenses for the Grand Forks and Williston regions today. Dispensary Permits, ... which will be doing business as Strive Life in Grand Forks, North Dakota. ...
(Date:11/16/2018)... ... 2018 , ... OnlineMasters.com, a trusted source for unbiased college ... physician assistant programs in the United States. The top-ranked programs were selected based ... graduate schools across the country with only the top 10 making it to ...
(Date:11/15/2018)... ... November 15, 2018 , ... November 13, ... platelet-rich plasma (PRP) therapies to her leading selection of minimally-invasive aesthetic treatments. PRP ... all-natural revitalization for any area of the body. Atagi Plastic Surgery & Skin ...
(Date:11/15/2018)... ... 2018 , ... Sift Healthcare, a revenue cycle intelligence company, ... including Wind River Financial, a Madison-based payment processing company. , The company, ... provide a range of solutions for healthcare organizations including claims workflow intelligence, reimbursement ...
Breaking Medicine News(10 mins):