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External Trigeminal Nerve Stimulation (eTNS) For Refractory Status Epilepticus
Date:3/25/2013

UCLA Department of Neurology, will present a case study in which external Trigeminal Nerve Stimulation (eTNS) was used successfully at UCLA as an adjunctive treatment of refractory status epilepticus on a patient who had failed multiple drug therapies prior to eTNS and was in a medication-induced coma. Subsequent to treatment with eTNS, the patient regained consciousness and was eventually discharged. This will be the first report of the potential clinical utility of eTNS as adjunctive treatment in refractory status epilepticus.

Given the portability of the Monarch eTNS System and its non-invasive nature, the case study suggests applicability of the Monarch as adjunctive treatment of refractory status epilepticus in an Intensive Care Unit (ICU) or emergency setting.

eTNS in the European Union

NeuroSigma's first TNS product, the Monarch™ eTNS™ System, is currently being marketed to patients in the European Union (EU), with a physician's prescription. In September 2012, NeuroSigma received CE Mark approval for the adjunctive treatment of epilepsy and major depressive disorder, for adults and children 9 years and older in the EU. The Monarch was recently unveiled in London at the 10th European Congress on Epileptology. The Monarch™ eTNS™ System consists of a small stimulator that can be placed in a pocket or worn at the waist, and an electric patch that is placed on the forehead. The patch stimulates the trigeminal nerve through the surface of the skin, and is used primarily while the patient is asleep.

Background - TNS

The trigeminal nerve is the largest cranial nerve, offering a high-bandwidth pathway for signals to enter the brain.  The trigeminal nerve projects to speci
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SOURCE NeuroSigma, Inc.
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