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Express Scripts Study Reveals Keys to Controlling Specialty Drug Costs

WASHINGTON, March 7, 2013 /PRNewswire/ -- A study presented today at the National Business Group on Health's (NBGH) Business Health Agenda 2013 conference in Washington, D.C., showed that, on average, employers that use multiple cost management programs had a 50 percent lower specialty drug trend than employers that did not use any specialty management programs.


The study, conducted by Express Scripts (NASDAQ: ESRX), is one of the first to examine the impact of multiple utilization management programs on the cost of specialty medications — a cost that is expected to account for $1 out of every $4 spent on prescription medications by 2014.

"Specialty drug costs and use have escalated without sufficient oversight to manage waste or misuse of these expensive medications. Add in the impact of bad health decisions and you get both poor financial and clinical outcomes," said Glen Stettin , MD, senior vice president, Clinical, Research & New Solutions, Express Scripts. "This data clearly demonstrates that multiple progressive management solutions mitigate the rising cost of specialty therapies by identifying and seizing cost-saving opportunities, as well as enabling better decisions that can lead to improved health outcomes."

Many key factors contribute to the rising costs of specialty medications for complex diseases such as cancer, hepatitis C and multiple sclerosis, including price inflation, increasing utilization and new drug introductions. In some cases, these medications can cost upwards of $100,000 per person per year.

Express Scripts researchers analyzed the specialty drug spending of 60 employer clients who are members of NBGH, representing more than 5 million Americans with pharmacy benefits. The employers were categorized into one of three groups based on the type of cost management programs adopted:

  • Unmanaged — employers whose health plan members could obtain their specialty medications from any pharmacy and did not use any specialty utilization management programs
  • Somewhat managed — employers whose health plan members used a specialty pharmacy exclusively and one specialty utilization management program
  • Tightly managed — consisting of employers whose health plan members used a specialty pharmacy exclusively combined with multiple specialty utilization management programs

Employers classified as unmanaged experienced an annual average increase in specialty drug spending per member per year of 27.8 percent. However, employers classified as tightly managed saw an annual increase in specialty drug spending per member per year of 13.6 percent, half that of the unmanaged group and nearly one-third lower than the average annual projected specialty drug trend. In addition, tightly managed programs saw higher average member adherence rates in top therapy classes such as multiple sclerosis and oncology.

Specialty Medications Require Specialized Management Solutions

According to the Express Scripts 2012 Drug Trend Report, the increase in spending on specialty drugs in 2012 was 18.4 percent, up slightly from 2011, which was 17.1 percent. Spending on traditional medications decreased for the first time to -1.5 percent, predominantly due to generics. Driving specialty medication trend in the top 10 therapy classes was unit costs, up 18.7 percent, while utilization was -0.4 percent. Specialty medications for inflammatory conditions, multiple sclerosis, cancer and HIV accounted for nearly 70 percent of annual spending on specialty drugs. In addition, hepatitis C virus (HCV), while having a relatively low per-member-per-year cost of $7.82, is the highest trending therapeutic category at 28.9 percent and is expected to increase rapidly with new therapy regimens and screening guidelines being implemented.

Nearly 50 percent of specialty drug costs are billed on the medical side of the plan benefit, where it is difficult to apply the various pharmacy benefit solutions that can effectively drive down costs.

Express Scripts, combining innovation from subsidiaries CuraScript and Accredo specialty pharmacies, is applying a unique new platform, Health Decision ScienceSM, to enable cost-effective, clinically appropriate health decisions that deliver improved patient care while reducing waste.

Express Scripts' comprehensive specialty offering, Specialty Benefit Services, includes clinical specialization through Accredo's disease-specific Therapeutic Resource Centers — where specialized pharmacists, nurses and other caregivers provide comprehensive patient care — clinically based formulary design, pharmacy-network and utilization-management solutions, and most importantly, a medical benefit-management solution that provides complete visibility into specialty drug spend, allowing for coordinated trend management by integrating both the pharmacy and medical data.

"Combining behavioral science with clinical specialization and actionable data creates an environment where the best health decisions become the easier decision for the patients, caregivers and health providers to make," Stettin said.

About Express Scripts

Express Scripts (NASDAQ: ESRX) manages more than a billion prescriptions each year for tens of millions of patients. On behalf of our clients — employers, health plans, unions and government health programs — we make the use of prescription drugs safer and more affordable. Express Scripts uniquely combines three capabilities — behavioral sciences, clinical specialization and actionable data — to create Health Decision ScienceSM, our innovative approach to help individuals make the best drug choices, pharmacy choices and health choices. Better decisions mean healthier outcomes.

Headquartered in St. Louis, Express Scripts provides integrated pharmacy benefit management services, including network-pharmacy claims processing, home delivery, specialty benefit management, benefit-design consultation, drug-utilization review, formulary management, and medical and drug data analysis services. The company also distributes a full range of biopharmaceutical products and provides extensive cost-management and patient-care services.

For more information, visit or follow @ExpressScripts on Twitter.


Ann Smith

SOURCE Express Scripts
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