Navigation Links
Experimental Drug Ketasyn(TM) Improves Memory in Age-Associated Memory Impairment Study
Date:8/29/2007

BROOMFIELD, Colo., Aug. 29 /PRNewswire/ -- Accera, Inc. announced today that recent data from a Phase II study of its lead compound Ketasyn(TM) (AC- 1202) in age-associated memory impairment (AAMI) showed that Ketasyn has a positive and clinically meaningful effect on memory in older adults.

AAMI is the decline in memory that occurs during the natural course of aging, The National Institute of Mental Health criteria for AAMI include complaints of gradual memory loss in everyday problems in persons more than 50 years of age. AAMI affects an estimated 10-15 million people in the U.S., and may be a precursor to Alzheimer's disease (AD), which is expected to afflict 11-16 million Americans in the next 40 years.

AAMI symptoms may be related to declines in glucose metabolism in the brain that are also associated with aging. Glucose is the brain's primary fuel source, so aging brains with impaired glucose metabolism require an alternative source of energy. Ketasyn is an orally available compound that is metabolized into ketone bodies, which the brain can use for energy even when its ability to process glucose is impaired.

"The results of this study support the hypothesis that providing additional energy reserves to the elderly brain improves a variety of cognitive activities. They also provide further evidence of the roles that glucose and insulin metabolism plays in cognition and memory," said Dr. Lauren Costantini, Accera's vice president of clinical development. "As in our earlier successful clinical studies in Alzheimer's disease, Ketasyn was well tolerated by subjects in the AAMI study and we are encouraged by the strong efficacy data."

The randomized, double-blind, placebo-controlled, parallel, multi-center trial was conducted at six centers in the United States. One hundred fifty- nine subjects diagnosed with AAMI received either Ketasyn or placebo for 90 days followed by a two-week washout period. Mean age in this study was 65. Subjec
'/>"/>

SOURCE Accera, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Trophos Publishes ALS Article in Journal of Pharmacology and Experimental Therapeutics
2. Alnylam Reports Results of Human Experimental Infection Model with Respiratory Syncytial Virus
3. Mayo Clinic News Release: Mayo Clinic-led Study Improves Breast Cancer Risk Prediction in Women with Atypia
4. ACE-011 Improves Multiple Myeloma Bone Disease in a Preclinical Model
5. Anastrozole (Arimidex) Improves Overall Survival in Postmenopausal Women with Early Breast Cancer Receiving Treatment with Tamoxifen
6. Actemra (tocilizumab) Significantly Improves Symptoms of Rheumatoid Arthritis Compared to a Current Standard of Care
7. Data Presented at SLEEP 2007 Shows VEC-162 Improves Sleep Onset and Maintenance vs. Placebo
8. Ivivis PEMF Technology Significantly Improves Neuron Survival in Parkinsons Disease Model, Study Finds
9. Study Shows Velcade Plus Doxil Improves Survival in Previously Treated Patients With Multiple Myeloma
10. Adding Thalidomide to Standard Therapy Improves Survival in Newly Diagnosed Multiple Myeloma Patients Over Age 75
11. First-of-Its-Kind Study Shows Botox (Botulinum Toxin Type A) Significantly Improves Idiopathic Detrusor Overactivity (IDO) in Patients With Symptoms of Overactive Bladder
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Quebec , Jan. 15, 2014  Valeant Pharmaceuticals International, ... announced that the applicable waiting period under the Hart-Scott-Rodino ... the previously announced tender offer by its indirect wholly-owned ... outstanding shares of common stock of Solta Medical, Inc. ...
(Date:1/15/2014)... 2014  A novel wearable injector slightly larger than an Oreo ... to self-inject prescription drugs in the large doses required to ... autoimmune deficiencies, and genetic disorders.  An emerging ... 2018, according to analysts.   Many of these drugs will require ...
(Date:1/14/2014)... The Brandeis Medical Center, led by Dr. Emmanuel Brandeis , ... laser tattoo removal experience with the advanced Astanza Duality laser and ... quality cosmetic services with cutting edge medical technology and offering expert ... has seen a dramatic increase in the presence of ...
Breaking Medicine Technology:Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... 2011 A new report in the March issue of ... beat brand names when it comes to safety, efficacy, and ... drug programs offering these drugs at prices as low as ... Walgreens, and Walmart have been steadily expanding their discount programs, ...
... JumpStart Ventures , the non-profit that invests in ... Ohio, and Cleveland Clinic , announced a ... Inc. The Cleveland-based company is developing a topical ... formation in wounds. (Logo: http://photos.prnewswire.com/prnh/20060209/CLJUMPSTARTLOGO) ...
Cached Medicine Technology:Consumer Reports Health: Best Drugs for What Ails You, Plus Where to Buy Them for $4 a Month 2Consumer Reports Health: Best Drugs for What Ails You, Plus Where to Buy Them for $4 a Month 3Consumer Reports Health: Best Drugs for What Ails You, Plus Where to Buy Them for $4 a Month 4JumpStart Ventures and Cleveland Clinic Invest in SironRX Therapeutics 2JumpStart Ventures and Cleveland Clinic Invest in SironRX Therapeutics 3JumpStart Ventures and Cleveland Clinic Invest in SironRX Therapeutics 4
(Date:7/9/2014)... users in Russia might contribute to HIV transmission ... by researchers from Boston University Schools of Medicine ... Pavlov State University, sought to discover the effect ... a cohort of HIV-positive people with lifetime of ... by police were more likely to share needlesincreasing ...
(Date:7/9/2014)... 8, 2014) Researchers from Montefiore Medical Center ... of Yeshiva University will present new findings at ... 12 July 17 in Copenhagen, Denmark. Data from ... prompt transition from cognitive normality to mild cognitive impairment ... Einstein Aging Study , established in 1980 to examine ...
(Date:7/9/2014)... organs in the human body. Its job is to ... is its synthesis function and that toxic substances ... detoxification function. Lack of exercise and too much alcohol, ... resulting diseased cells can lead to inflammations, cancerous ulcers, ... the German Liver Foundation, over five million people in ...
(Date:7/9/2014)... City, July 9, 2014 A study published in ... De Koninck and Robert Bonin, two researchers at Universit ... hypersensitivity using a new method that involves rekindling pain ... could lead to novel means to alleviate chronic pain. ... Universit Laval and Institut universitaire en sant mentale de ...
(Date:7/8/2014)... Department of Defense,s Defense Advanced Research Projects Agency ... to $2.5 million to develop an implantable neural ... neurons within the brain to help restore memory, ... builds on the understanding that memory is a ... the brain encode information, store it and retrieve ...
Breaking Medicine News(10 mins):Health News:BU researchers relate arrests with HIV risk environment 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 3Health News:Telemedicine for patients with chronic liver diseases 2Health News:Telemedicine for patients with chronic liver diseases 3Health News:Discovery of a new means to erase pain 2Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 2Health News:DARPA selects Lawrence Livermore to develop world's first neural device to restore memory 3
... FARMINGDALE, N.Y., Sept. 1 Misonix, Inc., (Nasdaq: ... technology, which in Europe is used for the ablation of ... the second expansion of its direct sales channel for the ... addition to its already established, commission based, contract sales organization, ...
... , ELM GROVE, Wis., Sept. 1 Compirion ... prevent child abuse. During the month of September, Compirion ... awareness of the devastating effects of abuse and neglect on our ... and more than two thousand die at the hands of those ...
... , , , ... community public health plan, today announced that it has received the Department ... a leader in quality care throughout the state of California for Medi-Cal ... and humbled by the recognition," said Dr. Kelly Pfeifer, SFHP Medical Director. ...
... , , ... launched its sixth season of the Thrive advertising campaign, with television, ... commitment to the total health of its members and the communities ... "Emerald Cities" and "Connected" -- illustrate Kaiser Permanente,s leadership in leveraging ...
... , , WASHINGTON, Sept. ... the country today announced an unprecedented alliance that will add ... group, Employers for Quality Health Care, is an independent coalition ... business groups like the U.S. Chamber of Commerce and the ...
... , , FDA won,t disclose brands; still ... FRANCISCO, Sept. 1 A study by the Food and Drug Administration found ... for Safe Cosmetics (CSC) in a 2007 study that received international attention. ... tested, at 0.09 to 3.06 parts per million - four times higher than ...
Cached Medicine News:Health News:Misonix Expands Sales Organization for Direct Sales of the SonicOne(TM) Wound Management System and the SonaStar(R) Ultrasonic Surgical Aspirator in the United States 2Health News:Misonix Expands Sales Organization for Direct Sales of the SonicOne(TM) Wound Management System and the SonaStar(R) Ultrasonic Surgical Aspirator in the United States 3Health News:Compirion Joins the Fight Against Child Abuse 2Health News:San Francisco Health Plan Recognized as Top Health Plan for Quality in the California Medi-Cal Program 2Health News:San Francisco Health Plan Recognized as Top Health Plan for Quality in the California Medi-Cal Program 3Health News:Kaiser Permanente Debuts New Ads Focused on Technology and Innovation 2Health News:Kaiser Permanente Debuts New Ads Focused on Technology and Innovation 3Health News:Employers Launch Grassroots Health Reform Coalition 2Health News:Employers Launch Grassroots Health Reform Coalition 3Health News:FDA Study: Lead Levels in Lipstick Much Higher Than Previously Reported 2
... indoor positioning supports patient safety by ... the right patients are in the ... Respond to the exact patient location ... monitor alarms. Measure patient flow times ...
... are preominantly used for routine blood collection. ... of the needle protective cap simplifies visual ... example, yellow symbolises the needle dimension 20 ... mm) and black 22 G (0.70 mm). ...
DiaMed-ID Micro Typing System...
Bio-Rad's ScanGel® cards for ABO reverse grouping, antibody screening and crossmatching include - ScanGel Neutral, ScanGel Coombs, Anti-IgG, -C3d (AHG), ScanGel Coombs + Neutral, ScanGel Anti-Ig...
Medicine Products: