Navigation Links
Exosome Diagnostics Presents Data Demonstrating Utility of Urine Exosome Technology to Predict Prostate Biopsy Outcome at American Urological Association Annual Meeting
Date:5/8/2013

officer of Exosome added, "These results are part of a multi-center clinical study program for EXO106, the first in vitro diagnostic in our exosome genitourinary (GU) oncology program.  EXO106 is being developed to provide patients and clinicians with a non-invasive diagnostic that can deliver real-time information following the finding of an elevated PSA.  We have now completed testing on over 1,000 urine samples from patient to characterize diagnostic performance."   

In the study presented by Dr. McKiernan, biopsy patients were divided into two cohorts. The first cohort was tested using a known prostate cancer biomarker, while a novel four-gene prostate cancer signature was tested in the second cohort.  Both groups were stratified based on whether their biopsies were positive or negative. Besides predicting positive biopsy outcome, exosome testing was able to distinguish histologically less aggressive, lower Gleason scores (≤7) cancers from those with higher, more aggressive Gleason scores (≥8). The results demonstrate that urinary exosome-derived RNA can be used to non-invasively evaluate gene expression in the prostate and accurately predict the likelihood of a positive or negative needle biopsy in addition to distinguishing more aggressive cancers.

This study was funded by the Prostate Cancer Foundation.

Exosome Diagnostics and its collaborators will also be presenting data on two other studies.

Abstract #13-7010, 3:30 to 5:30 p.m. PDT, May 6:  Urinary Exosomal RNA Provides a Non-Invasive Way to Accurately Detect PCA3 Expression in Men Undergoing Evaluation for Prostate Cancer,
Shapiro, E., Ahn, J.J., Zampella, B., Motamedinia, P., Scott, A., Salazar, G., Bate, K., Seaman, M., Badani, K., McKiernan, J.M., Russo L.
Exosome-derived PCA3 expression correlated well with the prostatic massage technique with a similar true positive rate.  Urinary exosome sampling captured
'/>"/>

SOURCE Exosome Diagnostics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Exosome Diagnostics Presents Data Demonstrating Clinical Applications of Exosome Technology in Brain Cancer, Prostate Cancer, and Alzheimers Disease at the International Society for Extracellular Vesicles 2013 Annual Meeting
2. Exosome Presents Late-Breaking Study Demonstrating Ability to Profile RNA from Archived Clinical Trial Blood Samples at 2013 American Association of Cancer Research Annual Meeting
3. Aethlon Medical Announces Notice of Allowance of U.S. Patent Application Covering a Medical Device to Remove Microvesicular Particles, Including Exosomes
4. Aethlon Medical (AEMD) Note: Cancer Research Discovery - Melanoma Exosomes Fuel Organ Metastasis
5. Algeta and Lumiphore Announce Further Expansion of Their Global Partnership for the Development of Targeted Alpha-pharmaceutical Cancer Therapeutics and Companion Diagnostics.
6. BD Diagnostics Advances Commitment to a Fully Integrated Microbiology Solution with New Agreement
7. Apnix Sleep Diagnostics Offering New Home Sleep Study Materials
8. LamdaGen Corporation Issued United States Patent for Diagnostics on Plasmonic-Based Nanosensors
9. Nipro Diagnostics Leverages Managed IT Services from JDL Technologies to Support Growth and Technological Innovation
10. 2013 Cancer Diagnostics Market Analysis: Cancer Testing Industry Growing Rapidly
11. Quest Diagnostics Reports First Quarter 2013 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/17/2014)... 2014 ... the addition of the  "China Interventional Cardiovascular ...      (Logo: http://photos.prnewswire.com/prnh/20130307/600769) ... China impacted by accelerated ... concept, dietary habit, way of working and ...
(Date:10/17/2014)... , October 17, 2014 ... Imaging Market by Technique (Optical Coherence Tomography, ... software) & by Application (Ophthalmology, Neurology, Oncology, Cardiology) - ... report studies the Optical Imaging market over ... was valued at $917.1 million in 2014 ...
(Date:10/17/2014)... 17, 2014 A victim of medical negligence at ... doctor with a history of alcohol abuse, a physician and ... Prop 46 today, highlighting how Prop 46 will identify and ... The ad pictures a doctor drinking at ... ER."  Proposition 46 will enact the first law in the ...
Breaking Medicine Technology:China Interventional Cardiovascular Device Industry Report 2014-2017 2China Interventional Cardiovascular Device Industry Report 2014-2017 3Optical Imaging Market Worth $1,669.2 Million by 2019 2Optical Imaging Market Worth $1,669.2 Million by 2019 3Optical Imaging Market Worth $1,669.2 Million by 2019 4Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 2Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 3Victim Of Negligence At Hands Of A Drunk Doctor, A Physician and Consumer Advocates Release New Yes on 46 TV Ad, "On Call" 4
(Date:10/19/2014)... The leading review website, Top10BestSEOHosting.com, has recently announced ... the best Dedicated Server Hosting suppliers. Their websites ... buy high quality hosting and save money at ... Top10BestSEOHosting.com says, “We believe that iPage and GreenGeeks ... lot of the global clients enjoy using their ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 This ... for Partial Seizure, complete with comparative analysis at ... of action (MoA), route of administration (RoA) and ... news and press releases. It also reviews key ... Seizure and special features on late-stage and discontinued ...
(Date:10/19/2014)... Fancyflyingfox.com, an innovative company that provides many kinds of ... of 2014 mother of the bride dresses . ... with big discounts, up to 70% off. All consumers ... this special offer. , Owing to the company’s ... of the leading brands in the global market. A ...
(Date:10/19/2014)... (PRWEB) October 20, 2014 Stephen T. Greenberg, ... been nominated for the 10th consecutive year as one of ... Dr. Greenberg was also been nominated as the best provider ... also nominated as best Day Spa and best Laser Treatment ... December 14th and readers can vote for the contest once ...
(Date:10/19/2014)... The U.S. Government has initiated a major effort ... 2025. However, a workgroup of nearly 40 Alzheimer,s ... the U.S. Government,s National Plan to Address Alzheimer,s ... scale, and adequately funded in order to successfully ... the workgroup to enlarge and strengthen the Plan ...
Breaking Medicine News(10 mins):Health News:Top10BestSEOHosting.com Considers iPage And GreenGeeks As The Best Dedicated Server Hosting Suppliers 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 2Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 3Health News:Partial Seizure Therapeutic Pipeline Market Review H2 2014 in a New Report Available at RnRMarketResearch.com 4Health News:Fancyflyingfox.com Updates Its Website With New Mother Of The Bride Dresses For 2014 2Health News:Dr. Stephen T. Greenberg – Nominated for the 10th Consecutive Year for One of Long Island’s Best Cosmetic Surgeons for 2015 by the Long Island Press 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 2Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 3Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 4Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 5Health News:Scientists say national Alzheimer's plan milestones must be strengthened to meet goal by 2025 6
... a direct link between a human gene and the risk ... by Professor Marco Polo from the National Centre of Investigative ... mutation in the gene, known as Cdk4, were more likely ... appear in the latest issue of the Proceedings of the ...
... developed a non-invasive diagnostic tool that can study changes ... the brain activity.This technique is based uopn near-infrared spectroscopy ... other methods such as functional magnetic resonance imaging and ... UI professor of Physics, whenever the region of the ...
... from Angina may have some new treatment options involving ... common cardiovascular disorder affecting millions of people all over ... vessels too clogged to get oxygen-rich blood to the ... or for more serious cases, rerouting the blood vessels ...
... responsible for imitation may be behind ,the unique quality to ... of empathy have now found brain regions involved in learning ... regions that are involved in human imitation and specific ,brain ... others.// , The research, ...
... researchers, Americans will probably have to depend on current ... this year Second-generation vaccines are in the works but ... that's ready to go, approved by the FDA.// ... of the anthrax vaccine to resume shipping after four ...
... human fat cells may become key to the development ... According to Dr. Lucino Roseveltte, professor of medicine at ... there are molecules produced by the fat cells, the ... functions of different organs. Their research identifies one very ...
Cached Medicine News:Health News:Studying brain anatomy without surgery 2Health News:Antibiotic, Gene Therapy Help Treat Angina 2Health News:Antibiotic, Gene Therapy Help Treat Angina 3Health News:Fat Cell Protein Hits Type-2 Diabetes 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: