Navigation Links
Exercise Performance in Children and Young Adults with Single Ventricle Heart Disease Improves with Use of Drug for Erectile Dysfunction
Date:3/10/2011

pposite treatment course.  As a "proof-of-concept" study, the researchers selected a relatively healthy cohort of subjects without significant complications that they felt would have sufficient exercise capacity to complete the study.

The researchers found significant improvements in exercise performance during treatment with sildenafil compared to placebo.  The findings included improved ventilatory efficiency and, in two subgroups of patients, an improved ability to perform moderate levels of exercise. These changes suggest an overall improvement in the physiology associated with this unique circulation.

"The enhanced exercise performance that we found in the study is exciting and may lead to an improvement in day to day activities for these children and young adults," Dr. Goldberg said.  "However, it is important to note that while the results of this study are encouraging, more work is needed to determine whether the short-term benefit found in this study holds up over a longer period of time and whether there are any long-term side effects," he added.

"If the results from this preliminary study are validated in a larger sample over a longer period of time, it may be that this medication has the potential to improve quality of life for patients born with only one ventricle," Dr. Goldberg concluded.

Dr. Goldberg's coauthors were Michael McBride, Ph.D., Bradley Marino, M.D., Nicole Mirarchi, M.D., Brian D. Hanna, M.D., Gil Wernovsky, M.D., Stephen M. Paridon, M.D., and Jack Rychik, M.D., all from The Children's Hospital of Philadelphia; and Benjamin French, M.D., from the University of Pennsylvania School of Medicine.

Grants from The Mark H. and Blanche M. Harrington Foundation and from Big Hearts to Little Hearts provided funding for this study. Dr. Goldberg received support from the NIH T32 grant HL07915.

About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in
'/>"/>

SOURCE The Children's Hospital of Philadelphia
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Dendreon Announces Exercise and Closing of Overallotment Option
2. EIB Active™ Campaign and Celebrity Nanny Jo Frost Kick Off 2011 in Los Angeles to Educate Families About Asthma and Exercise-Induced Bronchospasm (EIB)
3. Pharmasset Announces Exercise of Underwriters Overallotment Option
4. Amarin Announces Underwriters Exercise of Over-Allotment Option
5. American Council on Exercise (ACE) Announces Nationwide Effort to Eliminate Obesity in America
6. Cephalon Exercises its Option to Acquire BioAssets Development Corporation
7. Regeneron Announces Exercise of Over-Allotment Option and Closing of Underwritten Offering of Common Stock
8. MAP Pharmaceuticals Announces Exercise of Over-Allotment Option and Closing of Underwritten Offering of Common Stock
9. BioMed Realty Trust Announces Exercise of Over-Allotment Option for Common Stock
10. Advanced Life Sciences Receives $1.5 Million From Exercise of Unit Warrants and Secures Financing Commitment
11. ProUroCare Medical Announces Offering of Replacement Warrants in Exchange for Early Exercise of Outstanding Warrants
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... SUNNYVALE, Calif. , Nov. 20, 2014 /PRNewswire/ ... Study at the 2014 AAGL Global Congress demonstrates ... vaginal insert designed to provide bowel control. One of ... MD, Associate Professor and Division Chief of Urogynecology ... North Carolina, won an Award for Best Written ...
(Date:11/21/2014)... , Nov. 20, 2014   Wellcentive , ... (PHM) for healthcare organizations, announced today being named ... 2014 Intel Innovation Award .  Sponsored by Intel, ... in its fourth year, recognizes companies developing leading-edge ... healthcare delivery processes. Wellcentive,s ...
(Date:11/18/2014)... 18, 2014  Sanguine Biosciences – a biotechnology ... study recruitment – will use its proprietary mobile ... Pfizer Inc. find and recruit people diagnosed with ... members to participate in voluntary research, which will ... and hopefully aid in informing the development of ...
Breaking Medicine Technology:LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 2LIFE Study Prominently Featured at Minimally Invasive Gynecology Conference 3Wellcentive Named Finalist for 2014 Intel Innovation Award 2Wellcentive Named Finalist for 2014 Intel Innovation Award 3Sanguine's Mobile Application to Assist Recruitment for Pfizer Inc. Chronic Pain Research 2
(Date:11/21/2014)... November 21, 2014 For many busy people, ... office visits and months of recovery from dental surgery that ... even at the cost of their youthful appearance. , But ... Art Institute in Oxnard and Woodland Hills, Calif., can provide ... visit, even in instances where the patient’s bone has deteriorated. ...
(Date:11/21/2014)... MO (PRWEB) November 21, 2014 ... Melancholy Lift, an industry leader in the ... people have significant feelings of sadness and depression ... from traditional pharmaceutical choices. Often, prescription drugs can ... depression. Prescription drugs are expensive and require regular ...
(Date:11/21/2014)... Florida (PRWEB) November 21, 2014 Nature’s Sleep is ... Sleep contest . The contest calls for the creation of any ... a photo — that encompasses sleep, a bed or a mattress. ... year,” said Alan Hirschhorn, Vice President of Marketing for Nature’s Sleep, ... an array of more than 10,000 creative entries from some very ...
(Date:11/21/2014)... people with cochlear implants experience pain, discomfort and problems ... MRI scan, a new study finds. According to ... worldwide have cochlear implants, devices which provide a sense ... severe hearing loss. There have been prior reports of ... One expert said the problem is well-known among ...
(Date:11/18/2014)... 18, 2014 SnapMade , a ... for shoppers in this holiday season, celebrates the oncoming ... Commenting on the launch, Carl Beleek, Group Managing Director ... their customers both old and new in supporting them ... this opportunity to launch new ornaments to better serve ...
Breaking Medicine News(10 mins):Health News:Anacapa Dental Art Institute Prosthodontists Develop New Technique to Offer Younger Appearance in Just One Visit 2Health News:Anacapa Dental Art Institute Prosthodontists Develop New Technique to Offer Younger Appearance in Just One Visit 3Health News:Anacapa Dental Art Institute Prosthodontists Develop New Technique to Offer Younger Appearance in Just One Visit 4Health News:Anacapa Dental Art Institute Prosthodontists Develop New Technique to Offer Younger Appearance in Just One Visit 5Health News:Depression Relief Product Receives Top 5-Star Rating from TopConsumerReviews.com 2Health News:Nature’s Sleep Kicks Off their 2nd Art Of Sleep Contest 2Health News:MRI Can Be Painful, Disruptive for People With Cochlear Implants 2Health News:SnapMade Celebrates Christmas With Exciting New Launches 2
... NEW YORK, February 22 NexGen Biofuels Ltd.,(NASDAQ: ... its symbol to,"NXGN"., The company has changed its ... HCTL to NXGN, to more clearly reflect its new ... and to produce such,fuel through the acquisition of existing ...
... MELVILLE, N.Y., Feb. 22 /PRNewswire-FirstCall/-- Gentiva Health,Services, Inc. ... of,comprehensive home health and related services, announced today ... to 3:55 p.m. ET, Monday, March 3, 2008,at ... in,Orlando, Florida., The event will be available ...
... Calif., Feb. 22 Sutter Health is creating ... care and specialist,physicians committed to providing patients with ... The Sutter Medical Network,will have a presence in ... from Sonoma County to the Central Valley and ...
... Inclinix, Inc., an enrollment,contract research organization (CRO) and provider ... its,executive management team:, -- Steven M. Agnoff, has ... President of Marketing and Product Management. In this ... to the corporate marketing and product ...
... Physicians Coalition,for Injectable Safety has issued a statement ... after reports of serious complications,following treatment with Botox ... Botox(R) injections for cosmetic indications or,who are considering ... recent reports of adverse events, but must put ...
... IT, Sales and Large-Project Management ... Provider,s Partner Channel, BLOOMFIELD HILLS, Mich., Feb. ... (EHR) software and practice,management solutions provider serving healthcare ... has joined,gloStream,s executive management team as chief channel ...
Cached Medicine News:Health News:Gentiva(R) Health Services to Present March 3rd at Raymond James' 29th Annual Institutional Investors Conference in Orlando 2Health News:Gentiva(R) Health Services to Present March 3rd at Raymond James' 29th Annual Institutional Investors Conference in Orlando 3Health News:Sutter Health Launches Northern California Physician Network 2Health News:Sutter Health Launches Northern California Physician Network 3Health News:Inclinix, Inc. Announces Executive Management Team Changes 2Health News:Clarity for Consumers on Botox Complication and Death Reports 2Health News:Clarity for Consumers on Botox Complication and Death Reports 3Health News:Clarity for Consumers on Botox Complication and Death Reports 4Health News:Nationally Recognized Information Technology Veteran and Entrepreneur John Bamberger Joins gloStream, Inc. as Chief Channel Officer 2
Disposable tracheostomy care tray....
Disposable tracheostomy care tray....
... Solution For Your Tracheostomy Care Needs, ... features the latest components for efficient and ... task. Designed by clinicians, these latex-free trays ... patient and caregiver. All of our trays ...
... and alternate care facilities with a ... which offer the finest in nursing ... the guidance of experienced nursing personnel, ... what is required for efficient and ...
Medicine Products: