Navigation Links
Exenatide Once Weekly Provided Sustained Improvements in Glycemic Control With Weight Loss Over Two Years: DURATION-1 Interim Long-Term Data Presented at ADA 2009
Date:6/7/2009

Improvements in Systolic Blood Pressure and Triglycerides Also Observed

NEW ORLEANS, June 7 /PRNewswire-FirstCall/ -- Amylin Pharmaceuticals, Inc. (Nasdaq: AMLN), Eli Lilly and Company (NYSE: LLY), and Alkermes, Inc. (Nasdaq: ALKS) today announced long-term, interim results from the DURATION-1 study that showed sustained glucose control with weight loss, as well as improvements in systolic blood pressure and triglycerides, through two years of treatment with exenatide once weekly, an investigational therapy for type 2 diabetes. These findings were presented at the 69th Annual Scientific Sessions of the American Diabetes Association (ADA) in New Orleans. A New Drug Application (NDA) for exenatide once weekly was recently submitted to the U.S. Food and Drug Administration.

In the controlled portion of the open-label study, patients received exenatide once weekly or BYETTA(R) (exenatide) injection for 30 weeks, followed by 74 weeks of treatment with exenatide once weekly for all patients during an open-ended assessment period. Significant reductions in A1C of 1.7 percent and fasting plasma glucose (FPG) of 40 mg/dL were maintained after two years of treatment. Sixty-five percent of patients achieved an A1C of 7 percent or less. A1C of less than 7 percent is the target for good glucose control as recommended by the ADA. Body weight was significantly reduced, with patients losing an average of 5.8 pounds. Serum lipid profiles were significantly improved, and there was a significant reduction in systolic blood pressure (SBP).

"These two-year DURATION-1 data showed that maintenance of steady state concentrations of exenatide may res
'/>"/>

SOURCE Amylin Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Amylin and Lilly Announce Plans to Develop Pen Device for Exenatide Once Weekly
2. Exenatide Once Weekly Provided Superior Glucose Control With Weight Loss Compared to Sitagliptin or Pioglitazone in Head-to-Head DURATION-2 Study
3. Plans for Exenatide Once Weekly NDA Submission by End of First Half of 2009 Reaffirmed Following FDA Feedback
4. After One Year, Type 2 Diabetes Patients Taking Exenatide Once Weekly Sustained Improvements in Glycemic Control and Weight; DURATION-1 Presented at ADA 2008
5. Type 2 Diabetes Patients Taking Exenatide Once Weekly, a Phase 3 Investigational Diabetes Therapy, Showed Improvements in Glycemic Control, Weight
6. Monotherapy BYETTA(R) (exenatide) Injection Study Results Presented at ADA 2008 Showed Adults with Type 2 Diabetes Experienced Improved Glycemic Control and Weight Loss
7. One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function
8. One Year Study of Exenatide Treatment Showed Improved Beta-Cell Function
9. (RED) to Launch New Way for People to Get Music in Their Lives; Weekly Delivery of Great Music Helps to Save Lives in Africa
10. New Study Shows Once-Monthly Boniva(R) is as Clinically Effective as Once-Weekly Fosamax(R) at Increasing Bone Mineral Density in Postmenopausal Women With Osteoporosis
11. Nebulized Perforomist(TM) Inhalation Solution Provided Prolonged Bronchodilation and Increased Patient Satisfaction Compared to Albuterol/Ipratropium MDI
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... , Jan. 14, 2014  Luminex Corporation (Nasdaq: ... for the fourth quarter of 2013 on Monday, February 3, ... release after the close of trading. (Logo: ... call to discuss the operating highlights and financial results for ...
(Date:1/14/2014)... Pa. , Jan. 14, 2014 Dynamic Healthcare Services, ... announced today that it acquired Progressive Home Medical Equipment, Inc. ... 7, 2014. The terms of the acquisition were not disclosed. ... equipment ("DME") company providing a wide range of sleep, mobility, ...
(Date:1/14/2014)... , Jan. 14, 2014   NuAire , a manufacturer of ergonomically ... with Hitachi Koki of Japan ... North America . NuAire will utilize its network of ... Canada to offer assistance in application use, ...
Breaking Medicine Technology:Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 2Dynamic Healthcare Services Completes Progressive Home Medical Equipment of Clarion, PA Investment 3NuAire announces sales and service of Hitachi Koki centrifuges in North America 2
... Jan. 27 CardioGenics Holdings Inc. (OTC Bulletin ... in-vitro diagnostics segment of the Point-Of-Care (POC) diagnostic market, announced ... cartridge for its POC diagnostic device, the QL Care Analyzer. ... self-metering cartridge. , Dr. Yahia Gawad , CEO of ...
... , ... more than 30 years of research and an extensive open-label ... U.S. launch of Livea® , a doctor-developed, non-prescription, patent-pending ... the market. , (Photo: http://www.newscom.com/cgi-bin/prnh/20100127/NY44298 ) , ...
Cached Medicine Technology:CardioGenics Announces Completion of Cartridge Design for QL Care Analyzer 2CardioGenics Announces Completion of Cartridge Design for QL Care Analyzer 3WellWorld Science(R) Announces U.S. Launch of Livea(R),a Safe and Natural Appetite Control Supplement 2WellWorld Science(R) Announces U.S. Launch of Livea(R),a Safe and Natural Appetite Control Supplement 3WellWorld Science(R) Announces U.S. Launch of Livea(R),a Safe and Natural Appetite Control Supplement 4
(Date:4/17/2014)... 17, 2014) Two recent papers by a ... colleagues may help scientists develop treatments or vaccines ... Japanese encephalitis and other disease-causing flaviviruses. , Jeffrey ... molecular genetics at the School of Medicine and ... Medical Institute, and colleagues recently published articles in ...
(Date:4/17/2014)... Jon McCullers, MD, was recently invited to submit ... Nature Reviews Microbiology , one of the world,s ... infectious disease specialist, and chair of the Department ... Science Center, analyzed the epidemiology and microbiology of ... as well as more recent 2009 novel H1N1 ...
(Date:4/17/2014)... April 17, 2014U.S. military personnel who served in ... concussive traumatic brain injury (TBI) were compared to ... other medical reasons. Differences in measures of overall ... months after injury are reported in an article ... journal from Mary Ann Liebert, Inc., publishers. The ...
(Date:4/17/2014)... as 10 million older Americans suffer from depression, often ... However, new research a project that followed the ... years found that Internet use among the elderly ... 30 percent. , "That,s a very strong effect," said ... information studies and media who led the project. "And ...
(Date:4/17/2014)... April 17, 2014-- Colic affects about one in five ... numerous pediatric visits during the first several months after ... symptoms was showing promise; however, the April 1, 2014 ... Sung, Valerie) reported on a study, "Probiotics and Infant ... L reuteri for infant colic did not ...
Breaking Medicine News(10 mins):Health News:CU researchers discover target for treating dengue fever 2Health News:Long-term effects of battle-related 'blast plus impact' concussive TBI in US military 2Health News:Internet use can help ward off depression among elderly 2Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2
... Cadient Group, the,premier strategic interactive marketing agency ... been recognized as part of this,year,s Philadelphia 100(R). ... the fastest-growing, privately held companies in the Philadelphia,region., ... from 46 employees to more than,175, while revenues ...
... Health Plan announced today,that it has signed an ... to the Gateway Health Plan Medicare Assured(SM) managed ... is a Medicare,approved Special Needs Plan for Ohioans ... Under the agreement, effective October 1, 2008, Gateway ...
... Competition From Alternative Medicine and Relationships With Healthcare,Facilities ... WALTHAM, Mass., Oct. 27 Decision Resources, ... focusing on pharmaceutical and,healthcare issues, has made available ... presents the top 10 highlights of the Indian ...
... PLANO, Texas, Oct. 27 You loved your,very first ... promised and filled beautifully, but several months later you ... wrinkles creeping back in. Bear,in mind that if you ... your first, you will get your Restylane(R) beauty results ...
... Tough new steps must,be taken to prevent ... for Homecare, which today announced 13 specific recommendations,that ... to the home,medical equipment (HME) sector. The Association ... past year to adopt tougher, more effective,measures to ...
... TAMPA, Fla., Oct. 27 Relations PR & Marketing ... newest client,in the firm,s rapidly expanding roster of diverse ... forward to this partnership with Relations PR &,Marketing," said ... expertise is in line with our strategy to take ...
Cached Medicine News:Health News:Cadient Group Named to the Philadelphia 100(R) as One of the Region's Fastest-Growing Privately-Held Companies 2Health News:Gateway Health Plan(R) Signs New Agreement with Cleveland Clinic Hospitals 2Health News:Top 10 Things Pharma Should Know About India - Free Paper From Decision Resources 2Health News:Longer-Lasting Restylane(R) Beauty Results Confirmed 2Health News:Longer-Lasting Restylane(R) Beauty Results Confirmed 3Health News:American Association for Homecare Proposes Aggressive 13-Point Plan to Stop Medicare Fraud and Recoup Billions; Calls Steps Essential to Medicare's Health 2Health News:American Association for Homecare Proposes Aggressive 13-Point Plan to Stop Medicare Fraud and Recoup Billions; Calls Steps Essential to Medicare's Health 3Health News:American Association for Homecare Proposes Aggressive 13-Point Plan to Stop Medicare Fraud and Recoup Billions; Calls Steps Essential to Medicare's Health 4Health News:Relations PR & Marketing Named Agency of Record for Advanced Ultrasound Services 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: