Navigation Links
Everolimus (RAD001) Significantly Extends Progression-Free Survival in Advanced Kidney Cancer Patients After Failure of Other Targeted Therapy
Date:2/27/2008

r therapies.

Safety findings in the study were manageable and consistent with prior Phase II studies. Common adverse events in the study included mouth ulcers, high blood lipids, high blood sugar, skin rash, low red blood count, low phosphate levels, and inflammation of the lungs.

About Everolimus

Everolimus, an oral inhibitor of mTOR, is an investigational drug being studied in multiple tumor types. In cancer cells, everolimus inhibits mTOR, a protein that acts as a central regulator of tumor cell division, cell metabolism and blood vessel growth. Everolimus is a once-daily oral therapy that provides continuous inhibition of mTOR.

As an investigational compound, the safety and efficacy profile of everolimus has not yet been established in oncology. Access to everolimus is available only through carefully controlled and monitored clinical trials. These trials are designed to better understand the potential benefits and risks of the compound. Because of the uncertainty of clinical trials, there is no guarantee that everolimus will ever be commercially available for oncology indications anywhere in the world. Everolimus is approved under the trade-name Certican(R) for the prevention of organ rejection in heart and kidney transplant recipients. Certican was first approved in the EU in 2003 and is available in more than 60 countries.

Disclaimer

The foregoing release contains forward-looking statements that can be identified by terminology such as "to be", "planned", "may", "offers", "potential", "could", "possibilities", "will", or similar expressions, or by express or implied discussions regarding potential future approvals for everolimus or regarding potential future revenues from everolimus. Such forward-looking statements reflect the current views of the Company regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results with everolimus to be materially differen
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Abbotts XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
2. Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients
3. New Approach to Treating Anthrax Significantly Improves Survival Rates in Pivotal Efficacy Studies
4. TREANDA Significantly Improves Clinical Outcomes in Patients with Chronic Lymphocytic Leukemia Compared to Chlorambucil
5. Access Pharmaceuticals Demonstrates Ability to Significantly Reduce Glucose Levels in Pre-clinical Testing of Cobalamin(TM) Oral Insulin
6. Phase 3 Data Show New Anti-TNF, Golimumab, Significantly Improved Arthritis, Skin and Nail Manifestations in Patients with Psoriatic Arthritis
7. New Anti-TNF Golimumab Significantly Reduced Signs and Symptoms of Ankylosing Spondylitis According to Phase 3 Study Findings
8. CIMZIA(R) (certolizumab pegol), Significantly Reduces Structural Damage and Rheumatoid Arthritis Signs & Symptoms for Up to One Year
9. CV Therapeutics Anti-Ischemic Agent Ranexa(R) Significantly Reduces HbA1c and Other Markers of Diabetes in MERLIN TIMI-36
10. VIA Pharmaceuticals Presents Data at American Heart Association Meeting Showing VIA-2291 Significantly Reduces Inflammation in Preclinical Model of Atherosclerosis
11. A Sociolinguistic Analysis of In-Office Dialogue Reveals Psychiatrists and Parents Have Significantly Different Perceptions on ADHD and Psychiatric Comorbidities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)...  Edison Nation Medical, the premier healthcare innovation ... Association for Respiratory Care ( AARC ), the ... Nation Medical, which brings 12+ years experience working ... innovation ideas, will work with AARC to assist ... respiratory therapists in bringing their product innovation ideas ...
(Date:9/2/2014)... , Sept. 2, 2014  EMD Serono, Inc., a ... , announced today that Drew Young has ... Immunology. In this capacity, he will be responsible for ... Immunology franchise, including future products.   Bringing more ... marketing and sales efforts at pharmaceutical and biotech companies, ...
(Date:9/2/2014)... 2014 Actavis plc (NYSE: ACT ... Administration (FDA) has accepted for filing Actavis, New Drug ... treatment of diarrhea and abdominal pain in men and ... NDA for eluxadoline has been granted priority review status ... "The NDA filing of eluxadoline marks ...
Breaking Medicine Technology:Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 2Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 3EMD Serono Appoints Drew Young to Senior Vice President, Neurology and Immunology 2EMD Serono Appoints Drew Young to Senior Vice President, Neurology and Immunology 3EMD Serono Appoints Drew Young to Senior Vice President, Neurology and Immunology 4Actavis Announces FDA Acceptance for Filing of NDA for Eluxadoline 2Actavis Announces FDA Acceptance for Filing of NDA for Eluxadoline 3Actavis Announces FDA Acceptance for Filing of NDA for Eluxadoline 4
... (Nasdaq:  ARAY), a global leader in the field of ... institutions using CyberKnife radiosurgery in breast cancer treatment. These ... Fox Chase Cancer Center, will be presented at the ... Oncology (ASTRO) in San Diego from October 31 to ...
... 2010 Boehringer Ingelheim Pharmaceuticals, Inc. announced today results ... combination of two oral hepatitis C virus (HCV) compounds, ... BI 207127, with ribavirin reduced viral load below the ... The regimen did not include interferon through the first ...
Cached Medicine Technology:CyberKnife Radiosurgery for Early-Stage Breast Cancer 2CyberKnife Radiosurgery for Early-Stage Breast Cancer 3CyberKnife Radiosurgery for Early-Stage Breast Cancer 4CyberKnife Radiosurgery for Early-Stage Breast Cancer 5CyberKnife Radiosurgery for Early-Stage Breast Cancer 6Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 2Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 3Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 4
(Date:9/2/2014)... September 02, 2014 The Dream2Walk Foundation along ... on Sept. 14th, 2014 during Spinal Cord Injury Awareness Month ... Lynn England, and Chuck Ligon. Linear Automotive will be there ... show. , Doors open at 2pm. The car show is ... one free pass to the concert. There will be trophies ...
(Date:9/2/2014)... -- Melatonin supplements did not reduce delirium in seniors ... found. Many older hospital patients experience the sudden, ... their normal sleep-wake cycle. A lack of the hormone ... but there has been little research into whether melatonin ... 378 patients, average age 84, who had hip fracture ...
(Date:9/2/2014)... the levels of sex hormones in patients, blood may identify ... rhythm disorder that is fatal in 95 percent of patients. ... journal Heart Rhythm , shows that lower levels of ... who had a sudden cardiac arrest. Higher levels of estradiol, ... chances of having a sudden cardiac arrest in both men ...
(Date:9/2/2014)... Waco, TX (PRWEB) September 02, 2014 When ... any time day or night, leaving behind a path of ... tornado occurrences with an average of 1,253 tornadoes per year. ... be prepared in case a tornado strikes., , ... cellar, or interior room in your home with no windows ...
(Date:9/2/2014)... York, NY (PRWEB) September 02, 2014 ... VisitandCare.com , was designed to help doctors manage ... practices to boost patient conversion rates and clink revenue. ... a 60 percent increase in sales revenue and a ... one-of-a-kind CRM software in their own healthcare practices. , ...
Breaking Medicine News(10 mins):Health News:Gas Monkey Hosts Concert in Dallas Benefiting Dream2Walk Foundation with Linear Automotive 2Health News:Study links sex hormone levels in the blood to risk of sudden cardiac arrest 2Health News:Act Quickly in Case of Tornado: Rainbow International® Offers Tips on How to Be Prepared for a Tornado 2Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 2Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 3Health News:Doctors Abroad Using VisitandCare.com Patient Management Software Report 60% Increase in Revenue 4
... immediately call off their 20-day agitation against a new reservation ... court - which accepted a petition from the striking medicos ... its orders are not implemented. ,"We direct that ... should be called off forthwith," a vacation bench comprising Justice ...
... According to a research it has been found that in ... mandatory for everyone to maintain a regular exercise program//. ... the major of cause of death in men, which results ... which cholesterol-laden plaques build up in the arteries. As the ...
... According to a recent survey the young adults between the ... among the uninsured. The report by the Commonwealth Fund, a ... claim that in 2004, nearly 14 million Americans between 19 ... of 2.5 million since the year 2000. ,The ...
... falling standards of cleanliness despite Government promises to clean ... in 2002, only 52 percent reported about clean wards. ... very clean, but only 46 percent this year. Contradicting ... levels of general satisfaction with the health service. ...
... spread and growing variety of unregulated tobacco products, the ... broader regulation // to prevent more than five million ... agency also called for anti-tobacco programmes, especially aimed at ... apparently increasing. ,Tobacco use, it finds, also continued ...
... incidence of HIV/AIDS is declining in the western Indian state ... , Karnataka and Andhra Pradesh because of the proactive measures ... in the country, especially in the north, it is rising, ... released Tuesday, said that overall two-thirds of the people living ...
Cached Medicine News:Health News:More Number Of Younger Americans Lack Health Insurance 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: