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Everist Genomics Announces Worldwide Availability of OncoDefender™-CRC
Date:3/28/2011

k from those at low risk for cancer recurrence after potentially curative surgery.  For stages I/II colorectal cancer (n=115), OncoDefender-CRC correctly classified 32/46 cases of recurrence and 38/69 cases of non-recurrence (sensitivity 70%, specificity 55%).  'High risk' patients had a significantly higher probability of recurrence within 36 months than 'low risk' patients (PPV 0.51, NPV 0.73, HR 2.06 (95% CI: 1.10 to 3.86; p=0.020)). In contrast, the standard prognostic guidelines described by the National Comprehensive Cancer Network (NCCN) Clinical Practice Guidelines in Oncology were unable to differentiate recurrence risk in this population (p=0.315).  The high sensitivity and PPV of the test exceeds that for other prognostic tests that have been developed for early stage CRC, thereby providing improved identification of those patients at highest risk for recurrence.  

Despite the fact that diagnostic testing is said to influence 70% of all healthcare decisions, obtaining adequate reimbursement remains a significant concern for patients and their providers. (2)

To address this issue, Everist Genomics has developed a unique financial assistance program that will enable patients to obtain the testing they need regardless of insurance coverage or financial status.  Qualifying patients are eligible to have up to 80% of the cost of the OncoDefender-CRC test covered through one of Everist Genomics Financial Assistance programs.  

About Colorectal Cancer

Colorectal cancer is one of the major causes of cancer death worldwide, accounting for more than 150,000 new cases and 55,000 deaths in the United States every year and 125,000 deaths each year in Europe. (3)To date, surgery, followed by adjuvant chemotherapy when appropriate, is the mainstay of therapy for patients with localized disease.

Of the estimated 68,000 patients that will be diagnosed with early-stage colorectal cancer this year in th
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SOURCE Everist Genomics
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