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Everist Genomics Announces Worldwide Availability of OncoDefender™-CRC
Date:3/28/2011

natomical characteristics (e.g. tumor size, depth of tissue invasion and migration to other organs and tissues).  OncoDefender-CRC determines the tumor's aggressiveness based on its genetics makeup and molecular profile.  The clinical data indicate that the performance characteristics of the OncoDefender-CRC test are superior to other methods currently in use to predict recurrence.  Furthermore, studies demonstrate that high-risk OncoDefender-CRC results correlate with cohorts colorectal cancer patients that recur within 3 years of surgery, while low-risk results correlate more closely with those patients without recurrence within 3 years.  As a further indication of the overall accuracy and robustness of OncoDefender-CRC, the test does not report indeterminate or "no-call" results from any samples that meet quality acceptance and processing criteria.  

According to Peter F. Lenehan, M.D., Ph.D. Chief Medical Officer of Everist Genomics, accurate assessment of the risk of recurrence for Stage I and Stage II colorectal cancer patients addresses a significant unmet medical need.  "Knowing a patient's risk of recurrence after surgery directly informs decisions regarding post-operative treatment and the aggressiveness of follow-up," said Dr. Lenehan.  "Molecular prognostics are valuable tools that reflect a tumor's underlying biology better than traditional histopathological examination and staging.  The OncoDefender-CRC test is an important medical advance because it helps physicians identify aggressive tumors amongst stage I and II colorectal cancer patients.  Physicians now have a valuable new prognostic tool to help them identify patients at risk of recurrence and most likely to benefit from adjuvant therapy."

About the External Validation Study

The study confirmed that, in a patient population from four international sites, OncoDefender-CRC was able to differentiate those patients at high ris
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SOURCE Everist Genomics
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