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Everist Genomics Announces Acquisition of Angiologix, Inc.
Date:10/31/2011

essential to ensuring that blood flows properly throughout the body.  Over time, the effects of high blood pressure, cholesterol, stress, alcohol, smoking and genetics can damage endothelial cells, preventing them from performing their vital functions.  Eventually, this damage to the endothelial cells will result in accumulation of fatty deposits called plaque that can rupture or have their caps shear off, causing clots that lead to heart attacks. If endothelial dysfunction is detected early enough, interventions like risk factor modification and drug therapy may improve prognosis. (4)

"The clinical evidence of an association between endothelial dysfunction and atherosclerosis and CVD is very strong," said Prasad Sunkara, Ph.D., Chief Executive Officer of Everist Genomics. "By providing an accurate assessment of endothelial function, AngioDefender may help physicians and patients to make treatment decisions aimed at reducing the risk of these serious conditions."

Subject to securing the required regulatory approvals, Everist Genomics will commercialize AngioDefender globally, starting in Europe and India during the first quarter of 2012.The current 'gold standard' for assessing endothelial function utilizes ultrasound to perform a costly and complex assessment of flow mediated dilation (FMD) of the brachial artery (BA).  This type of assessment has several major limitations, such as requiring the use of expensive ultrasound equipment, a specialized ultrasound probe and a highly-trained technician. Due to these limitations, along with the time required to perform ultrasound based measurement of FMD, its use has been confined to research applications.  

AngioDefender overcomes these limitations by utilizing a patented noninvasive technology for assessing endothelial dysfunction that produces consistent results regardless of operator differences.  AngioDefender assesses endothelial dysfunction by measuring changes in volum
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SOURCE Everist Genomics
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