Navigation Links
European Lung Cancer Screening Trial Demonstrates New Inexpensive Strategy for Improving Accuracy of Diagnosis
Date:12/4/2009

WASHINGTON, Dec. 4 /PRNewswire-USNewswire/ -- A simple, inexpensive computer tool that measures volume changes in the size of suspicious nodules in the lungs picked up by a CT scanner can rule out non-cancerous ones with almost perfect accuracy and enable doctors to diagnose true cancers with fewer, less expensive and less invasive tests.

(Logo: http://www.newscom.com/cgi-bin/prnh/20081016/LCALOGO)

The new diagnostic guidelines are described in a paper published yesterday in the New England Journal of Medicine on the progress of large European lung cancer CT screening trial (NELSON) launched in the Netherlands and Belgium in 2004.

"For years, those of us on the front lines of managing this extremely lethal disease have seen firsthand the impact early detection can have on the patients we serve and the people who love and care for them," said Dr. Michael Vincent Smith, an Atlanta-Area thoracic surgeon, President-Elect of the Atlanta Medical Association and founder of the first lung cancer early detection program in the state of Georgia.

"This carefully executed trial in over 7000 screening participant provides insight into management modalities to assist practicing physicians who diagnose and treat lung cancers," he said.

Advances in imaging technology have enabled scanners to detect suspicious nodules in the lung smaller than a grain of rice, but how to determine which ones are cancerous without further expensive or invasive and potentially dangerous testing is the question.

NELSON collaborators addressed the issue by using volume measurement and volume doubling time as the criteria for further action, a concept first proposed by CT diagnostic pioneers with the International Early Lung Cancer Action Program.

The refined protocol can rule out non-cancer nodules with 99.9% accuracy and at the same time reduce the number of tests required to confirm cancer in a malignant nodule. In the NELSON trial, only 1% of positive cancers required a biopsy for confirmation.

"As a specialist treating lung cancer in a region of the country with some of the highest death rates, we welcome the widespread dissemination of studies like the Nelson Trial," says Dr. Smith.

"Studies like this lend greater credibility to our belief that patients enrolled in well-designed lung cancer early detection research programs based on high resolution Computed Tomography scanning will lead to generating conclusive proof of significant lung cancer mortality reduction."

The NELSON trial will continue to examine the mortality impact of CT screening by comparing the number of lung cancer deaths that occur among the 7557 people getting scans with a similar number of people who do not. In the United States, the National Lung Screening Trial is also looking at mortality differences between those screened with a chest x-ray and those screened with a CT scan.

Both trials are expected to be completed within the next three to five years.

SOURCE Lung Cancer Alliance


'/>"/>
SOURCE Lung Cancer Alliance
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. CV Therapeutics Announces Eight Abstracts Accepted for Presentation at the European Society of Cardiology Congress 2007
2. Boston Scientific Announces Schedule for European Society of Cardiology Congress 2007
3. European Experts Recommend Pregnant and Nursing Women Take More DHA - Every Day
4. Genasense(R) Data in Melanoma to be Presented in Opening Session at First Worldwide Melanoma Center Meeting of the European Association of Dermato-Oncology
5. Terumo Heart to Announce Results of European Clinical Trial of DuraHeart(TM) LVAS at European Association of Cardiothoracic Surgeons Meeting in September
6. Threshold Pharmaceuticals Announces Two Presentations on Glufosfamide at the 2007 European Cancer Conference (ECCO)
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Life Recovery Systems Receives European CE Mark Approval for Its ThermoSuit(R) System
9. Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer
10. European Unions CHMP Issues Positive Opinion on PEGINTRON(TM) Combination Therapy for Retreating Hepatitis C Patients Who Failed Previous Therapy
11. Positive Xeloda(R) Five-Year Overall Survival Study Data in the Adjuvant Treatment of Colon Cancer Presented at Leading European Cancer Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... -- Story Highlights: , ... health care industry is causing providers to review operating ... offers a suite of solutions for health care providers ... optimization: labor resource analysis, revenue cycle optimization and physician ... and better economics ...
(Date:6/24/2016)... CAMBRIDGE, Mass. , June 24, 2016 /PRNewswire/ ... the Spaulding Rehabilitation Network,s Dean Center for ... of Physical Medicine and Rehabilitation, MIT Hacking Medicine, ... Center for Innovation, today announced the five finalists ... Hackathon for Lyme disease.  More than 100 scientists, ...
(Date:6/24/2016)... BEIJING , June 24, 2016 Dehaier ... or the "Company"), which develops, markets and sells medical ... China , signed a strategic cooperation agreement with ... as "Hongyuan Supply Chain") on June 20, 2016, to ... Under the strategic cooperation agreement, Dehaier will leverage Hongyuan ...
Breaking Medicine Technology:
(Date:6/25/2016)... , ... June 25, 2016 , ... ... policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at ... on several important health care topics including advance care planning, healthcare costs and ...
(Date:6/25/2016)... ... ... As a lifelong Southern Californian, Dr. Omkar Marathe earned his Bachelors in ... School of Medicine at UCLA. He trained in Internal Medicine at Scripps Green Hospital ... at the UCLA-Olive View-Cedars Sinai program where he had the opportunity to train in ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... Francisco, CA (PRWEB) , ... June 24, 2016 ... ... CitiDent, is now offering micro-osteoperforation for accelerated orthodontic treatment. Dr. Cheng has extensive ... self-ligating Damon brackets , AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... to recognize Dr. Barry M. Weintraub as a prominent plastic surgeon and the ... in the world, and the most handsome men, look naturally attractive. Plastic surgery ...
Breaking Medicine News(10 mins):