Navigation Links
European Lung Cancer Screening Trial Demonstrates New Inexpensive Strategy for Improving Accuracy of Diagnosis
Date:12/4/2009

WASHINGTON, Dec. 4 /PRNewswire-USNewswire/ -- A simple, inexpensive computer tool that measures volume changes in the size of suspicious nodules in the lungs picked up by a CT scanner can rule out non-cancerous ones with almost perfect accuracy and enable doctors to diagnose true cancers with fewer, less expensive and less invasive tests.

(Logo: http://www.newscom.com/cgi-bin/prnh/20081016/LCALOGO)

The new diagnostic guidelines are described in a paper published yesterday in the New England Journal of Medicine on the progress of large European lung cancer CT screening trial (NELSON) launched in the Netherlands and Belgium in 2004.

"For years, those of us on the front lines of managing this extremely lethal disease have seen firsthand the impact early detection can have on the patients we serve and the people who love and care for them," said Dr. Michael Vincent Smith, an Atlanta-Area thoracic surgeon, President-Elect of the Atlanta Medical Association and founder of the first lung cancer early detection program in the state of Georgia.

"This carefully executed trial in over 7000 screening participant provides insight into management modalities to assist practicing physicians who diagnose and treat lung cancers," he said.

Advances in imaging technology have enabled scanners to detect suspicious nodules in the lung smaller than a grain of rice, but how to determine which ones are cancerous without further expensive or invasive and potentially dangerous testing is the question.

NELSON collaborators addressed the issue by using volume measurement and volume doubling time as the criteria for further action, a concept first proposed by CT diagnostic pioneers with the International Early Lung Cancer Action Program.

The refined protocol can rule out non-cancer nodules with 99.9% accuracy and at the same time reduce the number of tests required to confirm cancer in a malignant nodule. In the NELSON trial, only 1% of positive cancers required a biopsy for confirmation.

"As a specialist treating lung cancer in a region of the country with some of the highest death rates, we welcome the widespread dissemination of studies like the Nelson Trial," says Dr. Smith.

"Studies like this lend greater credibility to our belief that patients enrolled in well-designed lung cancer early detection research programs based on high resolution Computed Tomography scanning will lead to generating conclusive proof of significant lung cancer mortality reduction."

The NELSON trial will continue to examine the mortality impact of CT screening by comparing the number of lung cancer deaths that occur among the 7557 people getting scans with a similar number of people who do not. In the United States, the National Lung Screening Trial is also looking at mortality differences between those screened with a chest x-ray and those screened with a CT scan.

Both trials are expected to be completed within the next three to five years.

SOURCE Lung Cancer Alliance


'/>"/>
SOURCE Lung Cancer Alliance
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. CV Therapeutics Announces Eight Abstracts Accepted for Presentation at the European Society of Cardiology Congress 2007
2. Boston Scientific Announces Schedule for European Society of Cardiology Congress 2007
3. European Experts Recommend Pregnant and Nursing Women Take More DHA - Every Day
4. Genasense(R) Data in Melanoma to be Presented in Opening Session at First Worldwide Melanoma Center Meeting of the European Association of Dermato-Oncology
5. Terumo Heart to Announce Results of European Clinical Trial of DuraHeart(TM) LVAS at European Association of Cardiothoracic Surgeons Meeting in September
6. Threshold Pharmaceuticals Announces Two Presentations on Glufosfamide at the 2007 European Cancer Conference (ECCO)
7. Study Results for Aclidinium Bromide, a Novel Anticholinergic, Presented at European Respiratory Society Annual Congress
8. Life Recovery Systems Receives European CE Mark Approval for Its ThermoSuit(R) System
9. Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer
10. European Unions CHMP Issues Positive Opinion on PEGINTRON(TM) Combination Therapy for Retreating Hepatitis C Patients Who Failed Previous Therapy
11. Positive Xeloda(R) Five-Year Overall Survival Study Data in the Adjuvant Treatment of Colon Cancer Presented at Leading European Cancer Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... 2017 A ReportsnReports.com report says, over the ... as the global sales of Adcetris and Kadcyla have been witnessing ... drug conjugates market is driven by large number of ADC drugs ... window offered by ADCs. ... Browse 3 Tables and 94 Figures, 10 Major Company Profiles, ...
(Date:3/24/2017)... YORK , March 24, 2017 ... and Equipment stocks, which are: Neovasc Inc. (NASDAQ: NVCN), Hologic ... Heart Inc. (NASDAQ: SSH ). These companies are ... its prior gains on Thursday, March 23 rd , 2017, ... afternoon, while shares of health care companies in the S&P ...
(Date:3/24/2017)... 24, 2017  GenomeDx Biosciences today announced that six ... Decipher® Prostate Cancer Classifier tests will be presented at ... (EAU) Congress held March 24 to 28, 2017 in ... Congress is Europe,s largest urological ... the urological field. The abstract titled "Muscle ...
Breaking Medicine Technology:
(Date:3/23/2017)... ... 23, 2017 , ... A recent report from the National Council on Teacher ... NCTQ report suggests, based on a review of GPA and SAT/ACT requirements at 221 ... the U.S. It argues that this higher bar should be set by states, by ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... to their communities, 16 more public health departments have been awarded national accreditation ... another 4.5 million people into the expanding network of communities across the nation ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... Center at 10 North Broadway Avenue, will be an educational and exciting program ... instruction in the management of chronic pain. , Oklahoma is in a healthcare ...
(Date:3/23/2017)... and Grimsby, Ontario (PRWEB) , ... March 23, 2017 , ... The MBI “Hall of ... industry or whose acts have had a significant impact on the careers of all others ... Marketing with NRB Inc. was inducted into the MBI’s Hall of Fame. The induction ...
(Date:3/23/2017)... ... March 23, 2017 , ... Dilger-Maxwell ... of the Norwalk and Vermillion areas, celebrates the newest charity campaign in ... nonprofit, community-based substance abuse prevention and peer recovery support organization providing vital ...
Breaking Medicine News(10 mins):