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European Commission Designates MST-188 As An Orphan Medicinal Product
Date:3/25/2013

ST-188 in acute limb ischemia, a complication of peripheral arterial disease, in late 2013 or early 2014.  More information can be found on the Company's web site at www.masttherapeutics.com.

Forward Looking Statements

Mast Therapeutics cautions you that statements included in this press release that are not a description of historical facts are forward-looking statements that are based on the Company's current expectations and assumptions. Such forward-looking statements include, but are not limited to, statements regarding prospects for success of MST-188 development programs in and outside of the U.S., the Company's focus on and the potential for strategic alliances involving MST-188, the positive effects that the EMA's orphan designation may have on MST-188's regulatory, commercial and partnering prospects, including the potential for 10-year marketing exclusivity and for increasing partnering interest in the EU, and the potential benefits of partnering MST-188, including enabling its development in multiple countries, enhancing the overall commercial opportunity for MST-188 and funding its development within the U.S. Among the factors that could cause or contribute to material differences between the Company's actual results and expectations indicated by the forward-looking statements are risks and uncertainties that include, but are not limited to: the risk that, upon re-evaluation at the time of application to the EMA for marketing authorization, the COMP or the EC may determine that MST-188 for the treatment of sickle cell disease no longer meets the criteria for orphan designation, meaning that MST-188 would not benefit from the 10-year marketing exclusivity for authorized orphan medicines; the potential that partnering transactions involving MST-188 may not advance its development in other jurisdictions, enhance the overall commercial opportunity of the product candidate or help fund its de
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SOURCE Mast Therapeutics, Inc.
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