Navigation Links
Etirinotecan Pegol (NKTR-102) Passes Interim Efficacy Analysis for BEACON Pivotal Phase 3 Clinical Study in Patients with Metastatic Breast Cancer
Date:1/14/2014

and taxanes (AT) are the most active and widely used chemotherapeutic agents for breast cancer, but the increased use of these agents at an early stage of disease often renders tumors resistant to these drugs by the time the disease recurs, thereby reducing the number of treatment options for metastatic disease. Drugs used to treat patients who progress following AT treatment can have response rates as high as 20-30%; however, resistance develops rapidly and new agents with different mechanisms of action, such as topoisomerase I inhibitors, are needed to allow novel ways to overcome the problem of drug resistance. (4) There are currently no FDA-approved topoisomerase I inhibitors to treat breast cancer.

About Nektar
Nektar Therapeutics is a biopharmaceutical company developing novel therapeutics based on its PEGylation and advanced polymer conjugation technology platforms.  Nektar has a robust R&D pipeline of potentially high-value therapeutics in oncology, pain and other therapeutic areas. In the area of pain, Nektar has an exclusive worldwide license agreement with AstraZeneca for naloxegol (NKTR-118), an investigational drug candidate, which has been filed for regulatory approvals in the U.S., Europe and Canada as a once- daily, oral tablet for the treatment of opioid-induced constipation.  This agreement also includes NKTR-119, an earlier stage development program that is a co-formulation of naloxegol and an opioid.  NKTR-181, a novel mu-opioid analgesic candidate for chronic pain conditions, has completed Phase 2 development in osteoarthritis patients with chronic knee pain.  NKTR-192, a novel mu-opioid analgesic in development to treat acute pain is in Phase 1 clinical development.  In anti-infectives, Amikacin Inhale is in Phase 3 studies conducted by Bayer Healthcare as an adjunctive treatment for intubated and mechanically ventilated patients with Gram-negative pneum
'/>"/>

SOURCE Nektar Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Nektar Completes Enrollment in Phase 3 BEACON Study of Etirinotecan Pegol in Women With Metastatic Breast Cancer
2. Nektar Presents Target-Specific Biomarkers Being Assessed in Ongoing Phase 3 BEACON Study of Etirinotecan Pegol for the Treatment of Metastatic Breast Cancer at the 2013 American Society of Clinical Oncology Annual Meeting
3. Nektar Announces that FDA Grants Fast Track Designation to Etirinotecan Pegol (NKTR-102) for the Treatment of Metastatic Breast Cancer
4. Nektar Announces Initiation of Investigator-Sponsored Trial Evaluating Etirinotecan Pegol (NKTR-102) in Patients with Bevacizumab (Avastin)-resistant High-Grade Glioma
5. CAS REGISTRY(SM) surpasses 75 million small molecules
6. WuXi Manufacturing Facility Passes FDA Inspection
7. Tecfideras Patient Share at Three Months Postlaunch Surpasses That for Aubagio and Gilenya At the Same Stage of Their Launches
8. Emotivs Brainwear Technology To Track Cognitive Health Surpasses $1M Kickstarter Stretch Goal
9. The Leukemia & Lymphoma Society Co-Pay Assistance Fund Surpasses $200 Million
10. French Man with SynCardia Total Artificial Heart Surpasses Two Years of Support
11. NABPs .PHARMACY Proposal Passes Initial ICANN Evaluation
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... HOUSTON , TX and VANCOUVER , May ... "Company") (TSX-V: EPI) announced today that it has received notification ... in the US that the Company,s IND application, filed March ... by the FDA of additional chemistry and pharmaceutical data related ... and a Certificate of Analysis on drug product. ...
(Date:5/4/2015)... NEW HAVEN, Conn. , May 4, 2015 ... been chosen by the American Optometric Association (AOA) ... care delivery and outcomes for the millions of ... Measures and Outcomes Registry for Eyecare ... and will securely facilitate efficient secondary uses of ...
(Date:5/1/2015)... 2015   Intarcia Therapeutics, Inc. today announced ... Vice President, Human Resources, reporting directly to Kurt ... new key member of the senior leadership team, Mr. ... Team to assure the Company advances its business, brings ... core values and its dynamic culture. Another essential goal ...
Breaking Medicine Technology:ESSA Pharma Inc. Receives FDA Response on IND Application 2ESSA Pharma Inc. Receives FDA Response on IND Application 3ESSA Pharma Inc. Receives FDA Response on IND Application 4American Optometric Association, Prometheus Research to Create Transformative Health Outcomes Registry 2Intarcia Appoints James P. Brady Vice President, Human Resources 2Intarcia Appoints James P. Brady Vice President, Human Resources 3Intarcia Appoints James P. Brady Vice President, Human Resources 4
... 1, 2010 Flextronics (Nasdaq: FLEX ... a dedicated, 180,000 square foot facility in Senai, ... rise in demand from medical OEMs, while providing ... needs.  Flextronics Medical,s new clean room manufacturing, ISO13485 ...
... ... ... ... are keyed by longUrl, so we need to grab the first one. for (var r in data.results) { first_result ...
Cached Medicine Technology:Flextronics Medical to Open Malaysia Facility to Complement Existing Low-Cost Footprint and Support Growth for Manufacturing Services 2Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 2Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 3Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 4Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 5Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 6Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 7Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 8Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 9Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 10Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 11Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 12Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 13Abbott and Enanta Present Positive Initial Results from Phase 2 Study of ABT-450/r for Treatment of Hepatitis C 14
(Date:5/4/2015)... Sylvia Hawthorn-Deppen shared her experiences living ... remind others in similar situations that they were not alone, ... and Discovery of New Energy” (published by Balboa Press). This ... a renewed press campaign. , “I have spent nearly 60 ... Hawthorn-Deppen says. “As an adolescent I got into trouble with ...
(Date:5/4/2015)... 04, 2015 Fast on the heels ... Trace Amounts, and Allison Folmar, JD, join over 150 ... internationally. , On Sunday, May 24, the conference presents ... possible?" Are you interested in Ryan Hinds' recovery story? ... our war against autism was written by Marcia ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 Sara Soulati, ... physician practice management firm in Los Angeles associated with ... the patent-pending status of The Sara Soulati Health For ... in 2010, is a lifestyle modification and disease prevention ... 2015 to the U. S. Patents and Trademarks Office ...
(Date:5/3/2015)... CA (PRWEB) May 03, 2015 Leading ... (CFHI), announced it will be awarding the 2015 Harris ... Knight and Selemawit Ghebrendrias, are the deserving recipients of ... for global service, Harris Llewellyn Wofford. The two recipients ... and passion for global health. , CFHI is ...
(Date:5/3/2015)... San Mateo, CA (PRWEB) May 03, 2015 ... newest service, MnemeTherapy® at two upcoming area seminars. The ... during the PSA Annual Regional Stroke Conference to be ... will be offered on Wednesday, May 13 during the ... Crowne Plaza. , “These seminars offer an excellent ...
Breaking Medicine News(10 mins):Health News:Author launches new press campaign for 2012 book ‘Wheel’ 2Health News:Perhaps the most important information families touched by autism will ever hear is available this month at international conference in Chicago 2Health News:Perhaps the most important information families touched by autism will ever hear is available this month at international conference in Chicago 3Health News:Perhaps the most important information families touched by autism will ever hear is available this month at international conference in Chicago 4Health News:CEO Sara Soulati Announces Patent-Pending Designation For The Sara Soulati Health For Life Program 2Health News:SF-based Global Health Non-Profit Awards Harris Wofford Global Service Fellowship 2Health News:SF-based Global Health Non-Profit Awards Harris Wofford Global Service Fellowship 3Health News:NuevaCare Introduces MnemeTherapy® Approach to Care for Elderly Patients with Alzheimer’s, Stroke and Other Types of Neurodegenerative Conditions 2
... damage if used improperly , TUESDAY, June 30 (HealthDay ... that the maximum dose for Tylenol and other pain ... , The advisers recommended lowering the maximum dose of ... and other medications. , Part of the problem, according ...
... pandemic since April study , , FLEMINGTON, N.J., June ... that more than one-third of physicians (37%) reported that there ... could result in a catastrophic pandemic, the highest level since ... there was "somewhat of a risk" for a pandemic. , ...
... Foods , LLC announced today that it is voluntarily recalling ... its stores between May 9th and May 15th. This ... by the JBS Swift Beef Company, which yesterday voluntarily expanded ... be contaminated with E. coli 0157:H7 to approximately 380,000 pounds ...
... can lead to serious injury , , , ... thrill of skateboarding. They learn to master their skills of ... American College of Foot and Ankle Surgeons (ACFAS), such tricks, ... and ankle injuries. , , Foot and ankle ...
... [Brown University] A front portion of the brain that ... according to new Brown University research. This section of ... different pronunciations of the same speech sound (such as a ... have solved a mystery. "No two pronunciations of the ...
... , NEW YORK, June 30 A new report on ... singles out Hospital for Special Surgery as the only hospital ... surgical site infection (SSI) compared to the state average for ... as a best practice," said Thomas P. Sculco, M.D., surgeon-in-chief ...
Cached Medicine News:Health News:FDA Advisers Recommend Smaller Doses of Acetaminophen 2Health News:More than One-Third of Docs Say Risk Level Rising for Potential H1N1 Flu Pandemic 2Health News:More than One-Third of Docs Say Risk Level Rising for Potential H1N1 Flu Pandemic 3Health News:WinCo Foods Voluntarily Recalls Beef and Ground Beef Sold at Some Stores Between May 9 and May 15, 2009 Due to Possible Contamination 2Health News:Surgeons Warn: Skateboarding Tough on Feet, Ankles 2Health News:Brain section multitasks, handling phonetics and decision-making 2Health News:Hospital for Special Surgery is Only New York Hospital with Significantly Lower Surgical Site Infection Rate for Hip Replacement Compared to State Average 2
... The next generation Powerheart AED has ... our flagship, feature-rich AED offering. The ... new customer-friendly features such as more ... new lighter weight, redesigned form factor, ...
... Plus™ is the best EMR value for ... in mind, Charting Plus™ relies heavily on ... features to improve documentation quality and increase ... content is specific to your medical specialty. ...
... the vast information needs of orthopedics specialty. ... for common orthopedics complaints, history of present ... also includes orthopedics specific ICD and CPT ... charges and quickly generate electronic Superbill at ...
... Maximo, Model 7303, incorporates new advances in CRT ... Proven Marquis ICD Platform. With this device, ... in 9 seconds or less throughout the life ... (14% increase in longevity over InSync II Marquis) ...
Medicine Products: