Navigation Links
Essentialis Files Two New Patent Applications for Investigational Compound DCCR
Date:2/29/2012

SAN DIEGO, Feb. 29, 2012 /PRNewswire/ -- Essentialis, Inc. announced the February 27, 2012 filing of two new patent applications expanding the patent portfolio claiming its investigational triglyceride-lowering compound DCCR and new methods of using the drug.  The first is a continuation-in-part of a current application that includes data from the recently completed clinical trial, CT013; the second is a patent filing covering certain aspects of the use of DCCR in the treatment of very high triglycerides (VHTG).  The filing is the fourth patent application filed by Essentialis covering DCCR, and has the potential to extend patent protection on the product to 2033.  Essentialis already holds composition of matter protection for DCCR through 2028.

"With our portfolio of issued and pending patents, we already have very solid protection and these new applications will make our protection even stronger," said Aaron D. Berg, President and Chief Executive Officer, Essentialis, Inc. "We are targeting 2015 market availability for DCCR, and it is our hope to receive patent protection through 2033."

Essentialis already has two issued US patents (7,572,789 and 7,799,777) providing composition of matter protection to DCCR to 2028 and two granted European patents (EP1781265 and EP1968601) providing similar protection.  With the recent filings, Essentialis is prosecuting eight US patent applications.  The company is prosecuting these filings in all major pharmaceutical markets.  The current protection on the product includes claims to the active ingredient, pharmaceutical formulations, methods of manufacture, and a wide range of methods to treat multiple diseases.  In particular, the claims cover methods to treat dyslipidemia including co-formulation and co-administration with a range of drugs currently used in the treatment of patients with lipid disorders.  

About DCCR
DCCR is a proprietary crystalline salt of diazoxide in a controlled-release, once-a-day tablet formulation. It is in development for patients with very high triglyceride (TG) levels. Essentialis has completed an End-of-Phase 2 meeting with the FDA and has obtained an SPA covering a pivotal study. Essentialis expects to initiate Phase 3 clinical trials in 2012. DCCR is covered by multiple issued US and granted EU patents, which provide composition of matter protection until 2028. Essentialis has evaluated DCCR in several double-blind, placebo-controlled studies which demonstrated that the drug was well tolerated and that statistical significance for various endpoints was achieved in patients with elevated triglycerides. More than 100,000 patient-years of treatment with diazoxide help support the acceptable safety of DCCR.

About Essentialis, Inc.
Essentialis is a San Diego-headquartered pharmaceutical company focused on the development of breakthrough medicines targeted to the ATP-sensitive potassium channel, a metabolically regulated membrane protein whose modulation has potential to treat and prevent a wide range of cardiovascular and metabolic diseases. For more information visit http://essentialistherapeutics.com/

Contacts:

Kristie Kuhl
kkuhl@makovsky.com 
212.508.9642

Or

Aaron Berg 
aberg@essentialistherapeutics.com 
858-964-5022


'/>"/>
SOURCE Essentialis, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Essentialis Appoints Mahendra G. Shah, Ph.D., to Board of Directors
2. Essentialis Promotes Aaron Berg to Chief Executive Officer
3. Essentialis Strengthens Patent Protection of Its Novel ATP-Sensitive Potassium Channel Opener Portfolio
4. Essentialis to Submit SPA for Hypertriglyceridemia
5. Essentialis Meets Primary Endpoint in Phase 2b Trial of DCCR for Treatment of Hypertriglyceridemia and is Granted Extensive Patent Coverage in the US
6. Essentialis Completes Patient Enrollment in Phase 2 Trial of DDCR for Treatment of Dyslipidemia
7. Bionovo Files Registration Statement for Offering of Convertible Preferred Stock and Warrants
8. ReBuilder (RBRM) Files Complaints Against Stock Traders
9. Acella Pharmaceuticals, LLC, Files Abbreviated New Drug Application (ANDA) With the U.S. Food & Drug Administration
10. Natural Alternatives International, Inc. Files Patent Infringement Claim Against DNP International Co., Inc.
11. Department of Justice files consent decree of permanent injunction against Ranbaxy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... study highlights the necessity of health literacy within the technology advancement of diagnostic imaging. According ... , a majority of oncology patients undergo imaging screenings without understanding the nuanced risks ... ... ... Medical Diagnostic Imaging Ampronix ...
(Date:5/27/2016)... May 27, 2016 According to ... hypertension is driving ambulatory blood pressure monitoring system market ... and their ability to respond to different pressure rates, ... can lead to various cardiovascular disorders such as heart ... These diseases are growing in prevalence each year. WHO ...
(Date:5/27/2016)... 27, 2016 Kitov ... focused on late-stage drug development, today announced the ... of pivotal batches required for registration of KIT-302 ... This follows Kitov,s announcement in December ... met its primary efficacy endpoint. "We ...
Breaking Medicine Technology:
(Date:5/31/2016)... ... May 31, 2016 , ... Fire Door Solutions, headquartered ... the Fire Door Solutions’ team. Keith will serve Fire Door Solutions as ... re-labeling. He will be instrumental in developing educational curriculum and leading training ...
(Date:5/31/2016)... ... 31, 2016 , ... Throughout the day, adults often find themselves reaching for a cup of ... they could be reaching for instead is a cup of Matcha green tea. Matcha is ... This sacred tea is harvested from early June to mid-July, when the leaves are the ...
(Date:5/31/2016)... Atlanta, GA (PRWEB) , ... May 31, 2016 ... ... Contact Center Solutions , today announced it has been included by Gartner, ... 2016 report mentions a wide range of Contact Center Infrastructure technologies, some of ...
(Date:5/31/2016)... ... May 31, 2016 , ... ... Healthconnect’s (Healthconnect) regional health information exchange, which enables physicians at SJMC’s two hospital ... patients from other participating organizations in the exchange. SJMC’s membership in the health ...
(Date:5/31/2016)... (PRWEB) , ... May 31, 2016 , ... ... using a mix of advanced Artificial Intelligence (AI) and the latest in ... The medical center is integrating predictive analytic outputs directly into the clinical workflow. ...
Breaking Medicine News(10 mins):