Navigation Links
Essentialis Appoints Mahendra G. Shah, Ph.D., to Board of Directors
Date:1/5/2012

SAN DIEGO, Jan. 5, 2012 /PRNewswire/ -- Essentialis, Inc., today announced the appointment of Mahendra G. Shah, Ph.D., a partner with the life sciences-focused venture capital firm Vivo Ventures, to its Board of Directors.  A biopharma executive noted for his expertise in business development and economic strategies, Dr. Shah becomes the sixth member of the Board of Directors for Essentialis, a company focused on the development of a breakthrough medicine for the treatment of cardiovascular and metabolic disease.  Its lead compound, DCCR, is now in Phase IIb trials for patients with very high triglycerides. 

"Dr. Shah brings to Essentialis his tested knowledge in business development, clinical design and pharma-board leadership," said Stuart Collinson, Ph.D., Chairman of the Board, Essentialis.  "Essentialis expects to release its Phase IIb trial data for DCCR in the coming weeks.  As we prepare to begin a new chapter with an exciting new compound for further evaluation, board members with Dr. Shah's range of experience will advance our development objectives."

Essentialis added Dr. Richard Pasternak, a renowned cardiologist and former Merck & Co., Inc. executive, and Mr. Aaron Berg, Essentialis president, who was recently promoted to Chief Executive Officer, to its board of directors in December 2011.

About Mahendra G. Shah, Ph.D.

Mahendra G, Shah, Ph.D., has been a venture partner at Vivo Ventures, a life sciences-focused venture fund, since March 2010.  Prior to joining Vivo Ventures, he served as chief executive for several biopharma companies.  From September 2005 to December 2009, he was the founder, chairman and CEO of Nextwave Pharmaceuticals Pediatric, a specialty biomedical company.  From 1993 to 2003, he served as chairman and CEO of First Horizon Pharmaceuticals, a publicly traded specialty pharmaceutical company, where he raised more than $200 million in the public market and built a profitable company with sales exceeding $150 million.  Achieving its business objectives, First Horizon (renamed Sciele) was acquired by Shionogi Pharmaceutical Company for $1.4 billion in 2008.  Dr. Shah also served as the senior director of new business development with Fujisawa USA (Astellas) from 1987 to 1991; prior to that, he served in scientific and management positions with Schering-Plough and Bristol Myers-Squibb Company.

Dr. Shah has served on the boards of Unimed Pharmaceuticals (UMED), Introgen Therapeutics Inc., Inpharmakon, Inc., Protomed Inc., Structural Bioinformatics Inc., and Zarix Inc. He received his Ph.D. in industrial pharmacy from St. John's University and his Bachelors and Masters Degree in Pharmacy from L.M. College of Pharmacy in Gujarat, India.

About DCCR

DCCR is a proprietary crystalline salt of diazoxide in a controlled-release, once-a-day tablet formulation, currently in development for patients with very high triglycerides. Essentialis expects to initiate Phase III clinical trials in 2012.  DCCR is covered by multiple issued US patents, which provide composition of matter protection until 2028.  Essentialis has evaluated DCCR in double-blind, placebo-controlled studies that demonstrated the drug was well tolerated, and achieved various statistically significant endpoints in patients with elevated triglycerides. More than 100,000 patient-years of treatment with diazoxide during the last 40 years, and more than 3,000 peer reviewed publications covering in-vitro, animal model and clinical results with diazoxide, support the acceptable safety of DCCR.

About Essentialis, Inc.

Essentialis is a San Diego-headquartered pharmaceutical company focused on the development of breakthrough medicines targeted to the ATP-sensitive potassium channel, a metabolically regulated membrane protein whose modulation has potential to treat and prevent a wide range of cardiovascular and metabolic diseases.  For more information visit http://essentialistherapeutics.com/

Contacts:

Kristie Kuhl
kkuhl@makovsky.com 
212-508-9642

Or

Aaron Berg
aberg@essentialistherapeutics.com 
858-964-5022


'/>"/>
SOURCE Essentialis, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Essentialis Promotes Aaron Berg to Chief Executive Officer
2. Essentialis Strengthens Patent Protection of Its Novel ATP-Sensitive Potassium Channel Opener Portfolio
3. Essentialis to Submit SPA for Hypertriglyceridemia
4. Essentialis Meets Primary Endpoint in Phase 2b Trial of DCCR for Treatment of Hypertriglyceridemia and is Granted Extensive Patent Coverage in the US
5. Essentialis Completes Patient Enrollment in Phase 2 Trial of DDCR for Treatment of Dyslipidemia
6. PrimeraDx Appoints David Jackson as VP of Business Development
7. China Health Resource Appoints USA Acquisition Counsel
8. Winner Medical Appoints BDO China as Independent Auditor
9. Marken Appoints New Head of Global Quality Assurance
10. Delcath Appoints Gregory Gores, M.D. to Medical Advisory Board
11. Qforma Appoints Ian McGuinness as Vice President, Business Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/31/2016)... -- , Isansys  Lifecare, a new generation digital ... wireless patient monitoring platform, as it ships more systems to ... , Scotland and Norway ... system, launched earlier this year, is now being used in ... This new technology significantly enhances the user experience and ...
(Date:5/30/2016)... 2016 According to a ... Market by Type (Stability, Raw Materials, Method Validation, ... (Pharmaceutical Companies, Medical Device Companies) - Global Forecast ... healthy growth during the last decade and is ... between 2016 and 2021 to reach USD 4.13 ...
(Date:5/30/2016)... , May 30, 2016 Eye expert ... of premature babies to seek an eye examination ... condition     Moorfields Eye Hospital Dubai, ... London , has identified premature babies as a ... because of their particular vulnerability to retinopathy of prematurity (ROP). ROP ...
Breaking Medicine Technology:
(Date:5/31/2016)... ... , ... Dr. Charles A. Ditta attained his Doctor of Medical Dentistry Degree ... 1986, where he graduated in the top ten percentile of his class. Dr. Ditta ... He has been a member in good standing for thirty years in the American ...
(Date:5/31/2016)... ... May 31, 2016 , ... ... on patients with cancer, has added Cancer and Careers to its ... more timely content on continuing successful careers while fighting cancer. , As partners, ...
(Date:5/30/2016)... ... May 30, 2016 , ... ... inside of FCPX," said Christina Austin - CEO of Pixel Film Studios. ... within Final Cut Pro X. Choose from abstract transitions to more simple wipes ...
(Date:5/30/2016)... Texas (PRWEB) , ... May 30, 2016 , ... Another ... 7 am in Plano, located at 3960 Legacy Drive, Plano, TX and is open ... Plano Chamber of Commerce followed by a medical open house. The Jasper High School ...
(Date:5/29/2016)... Viejo, CA (PRWEB) , ... May 29, 2016 , ... ... Volume 3 let's the user control the style of their project," said Christina Austin ... set of 30 self-animating web-themed intros created exclusively for use in Final Cut Pro ...
Breaking Medicine News(10 mins):