Navigation Links
Epizyme Receives Orphan Drug Designation for EPZ-5676
Date:8/16/2013

l exclusively enroll MLL-r patients.

Epizyme retains all U.S. rights to EPZ-5676 and has granted Celgene an exclusive license to EPZ-5676 outside of the United States. Epizyme has partnered with Abbott to develop a companion diagnostic to identify MLL-r patients. Additional information about these partnerships may be found here: http://www.epizyme.com/about-us/partnerships.asp

About MLL-r

MLL-r is an aggressive subtype of two of the most common forms of acute leukemia, acute myelogenous leukemia (AML) and acute lymphoblastic leukemia (ALL). The disease predominantly occurs in two different age ranges, an adult population and a pediatric population. Although both age ranges share a common genetic driver, the adult disease is frequently a secondary leukemia resulting from prior chemotherapy for a different, unrelated cancer, while the pediatric disease is sporadic in nature. According to research published in the journal Blood in December 2002, the five-year overall survival rate for adult patients with the MLL-r subtype of AML ranges from approximately 5 to 24 percent. The five-year event-free survival rate in pediatric patients with the most common MLL-r subtype of ALL is approximately 27 percent, as identified in research published in the New England Journal of Medicine in 2004. The total annual incidence of MLL-r in all patients (adult and pediatric, AML and ALL) in major pharmaceutical markets is approximately 4,900 patients, according to a report by Clarion Healthcare commissioned by Epizyme. Patients with MLL-r are routinely diagnosed today with existing tests that are commonly used in clinical settings, and there is high awareness of MLL-r among oncologists.

About Epizyme, Inc.

Epizyme, Inc. is a clinical stage biopharmaceutical company creating personalized therapeutics for patients with genetically defined cancers.
'/>"/>

SOURCE Epizyme, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Epizyme Publishes Current Review on Targeting Protein Methyltransferases for Personalized Cancer Therapeutics
2. Epizyme to Present at Upcoming Conferences in February
3. Epizyme to Partner to Develop DOT1L Companion Diagnostic
4. Epizyme, Inc. Files Registration Statement for Proposed Initial Public Offering
5. Epizyme, Inc. Announces Pricing of Initial Public Offering
6. Epizyme Enrolls First Patient in Phase 1/2 Clinical Trial of EPZ-6438, an Inhibitor of EZH2
7. Epizyme, Inc. to Webcast Conference Call Discussing Second Quarter 2013 Financial Results on July 31, 2013
8. Epizyme, Inc. to Present at Wedbush Securities Life Sciences Management Access Conference in August
9. PAREXEL Chief Operating Officer Dr. Mark A. Goldberg Receives Special Recognition Award
10. Leica Biosystems Receives FDA Approval for the Fully Automated Bond Oracle™ HER2 IHC System on the Leica BOND-MAX
11. Nephros Receives 510(k) Clearance for Hemodiafiltration System
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... -- Inventor of ProTide technology ...   NuCana, a clinical stage biopharmaceutical company ... portfolio of novel anti-cancer medicines, today announced the appointment ... Officer. Professor McGuigan was the original inventor ... Medicinal Chemistry at the Cardiff School of Pharmacy and ...
(Date:6/30/2015)... BRUSSELS , July 1, 2015 ... proud to announce the winners of the first Ansell ... European Operating Room (O.R.) Nurses. The 2015 award, organised ... (EORNA), recognizes perioperative nurses who display exceptional skill and ... to staff education and development. Award ceremonies are taking ...
(Date:6/30/2015)... , June 30, 2015  The MEDevice San ... year, is an event dedicated to bringing medtech professionals ... issues and topics affecting the industry today. This year,s ... the challenges and opportunities facing today,s medtech professional in ... and to register for MEDevice San Diego, please visit: ...
Breaking Medicine Technology:Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 2Internationally Renowned Medicinal Chemist Professor Chris McGuigan Appointed as NuCana's Chief Scientific Officer 3Ansell Announces European O.R. Nurse Hero Award Winners 2Ansell Announces European O.R. Nurse Hero Award Winners 3MEDevice San Diego 2015 Attracts High-Tech Medical Industry 2
(Date:6/30/2015)... Valley, California (PRWEB) , ... June 30, 2015 ... ... of the year, it has proven its continuing growth as a Master Franchisor. ... On June 17th, the Simi Valley Chamber of Commerce Ambassadors headed by Keith ...
(Date:6/30/2015)... ... 2015 , ... White Blitz , a professional teeth whitening company catering ... teeth whitening entrepreneurs. Mobile teeth whitening is a newer trend in cosmetics and draws ... The popularity of the industry has spawn full-blown mobile whitening operations as well as ...
(Date:6/30/2015)... ... 30, 2015 , ... Memphis, TN: Electronic Security Specialists (ESSC) provides ... of their top 20 installing dealers for the first quarter of 2015. ESSC ... on timeliness, service, installation, paperwork and customer satisfaction. , ESSC which formed in ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... Ticket Down is a reliable source for ... Stadium in Provo, Utah. This legendary band has been packing venues for years and ... have also released more than 20 albums in their career. While Journey is known ...
(Date:6/30/2015)... (PRWEB) , ... June 30, 2015 , ... ... in Webster, Texas have launched a ‘responsive design’ website to inform potential sinus ... to cure them. , The website includes information about a wide variety of ...
Breaking Medicine News(10 mins):Health News:1Heart Caregiver Services® Simi Valley Grand Opening 2Health News:1Heart Caregiver Services® Simi Valley Grand Opening 3Health News:1Heart Caregiver Services® Simi Valley Grand Opening 4Health News:White Blitz to Develop New Mobile Teeth Whitening Program for Entrepreneurs 2Health News:Electronic Security Specialists (E.S.S.C. Inc) Awarded Top Service Provider Award By Monitronics 2Health News:Journey Tickets at The Stadium of Fire at Lavell Edwards Stadium in Provo, Utah: Ticket Down Slashes Ticket Prices for Journey on the 4th of July in Provo 2Health News:Clear Lake Medical Center ENT Launches ‘Responsive Design’ Website 2Health News:Clear Lake Medical Center ENT Launches ‘Responsive Design’ Website 3
... BIRMINGHAM, Ala. Young hunters between the ages of 15 ... in tree stand-related incidents, say researchers at the University of ... same researchers, findings, though, suggest that such injuries are preventable. ... Journal of TRAUMA Injury, Infection and Critical Care , reports ...
... study finds , WEDNESDAY, Dec. 30 (HealthDay News) -- ... of early emphysema when they become nonsmoking adults, perhaps ... exposure, new research suggests. , Researchers reached their ... six communities in the United States. About half of ...
... N.Y., Dec. 30 Nutrition 21, Inc. (OTC Bulletin Board: ... dietary supplement, and functional food and beverage markets announced today ... its direct response and retail businesses to Nature,s Products, Inc., ... million plus the assumption of designated liabilities. , Nutrition ...
... zest for sports, experts say, , WEDNESDAY, Dec. 30 (HealthDay ... active. When they are, they,re less likely to be overweight ... , But how do you get kids moving? And not ... Therein lies the rub. , Obesity is at epidemic proportions ...
... , WASHINGTON, Dec. 30, Major ... Sharing Miracles - a 30-minute public affairs television program that ... airs every week on more than 300 television stations nationwide. ... have three generations play in the major leagues (grandfather Ray, father Bob ...
... 1, Health Carrier Review Act Puts New Resource on the ... Carrier , BOISE, Idaho, Dec. 30 Idaho consumers ... necessary health and medical services will have a new tool ... Health Carrier External Review Act, starting January 1, the Idaho ...
Cached Medicine News:Health News:Young hunters most likely to be injured using tree stands, say UAB researchers 2Health News:Nutrition 21 Completes Sale of Direct Response and Retail Businesses to Nature's Products, Inc. 2Health News:For Kids, All Activity May Not Be Equal 2Health News:For Kids, All Activity May Not Be Equal 3Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 2Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 3Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 4Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 5Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 6Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 7Health News:'Sharing Miracles' Television Program to Feature Major League Baseball Star Aaron Boone 8Health News:AARP Commends Idaho for Tackling Wrongfully Denied Health Claims 2
For the quantitative determination of uric acid in serum....
For determination of uric acid in serum, plasma or urine. For Hitachi 704 / 911. Available with Calibrator: Trucal U and controls: Trulab N and Trulab P....
For the quantitative determination of uric acid in serum....
For the quantitative determination of Uric Acid in serum. Linearity: 25 mg/dl....
Medicine Products: