Navigation Links
EpiVax-Novozymes Tregitope-Albumin Fusion Moves 'Paradigm-Shifting' Treatment for Diabetes Closer to Clinical Trials
Date:2/12/2013

PROVIDENCE, R.I., Feb. 12, 2013 /PRNewswire/ -- EpiVax, Inc. is pleased to announce a new Collaborative Research Agreement with Novozymes Biopharma. The collaboration will enable EpiVax to rapidly advance its Tregitope immune-modulating technology as a potential treatment for autoimmune diseases. When used as a buffering agent, albumin has excellent safety and pharmacokinetic profiles. Fusing Tregitopes to Novozymes' proven albumin-based half-life extension platform will create a safe and effective vehicle for the application of Tregitopes to multiple problems in the areas of autoimmunity, transplantation, and allergy.

(Logo: http://photos.prnewswire.com/prnh/20121116/NE15175LOGO )

Tregitopes, discovered by Anne De Groot and Bill Martin at EpiVax, are linear sequences of amino acids contained within the framework of monoclonal antibodies and immunoglobulin G; the original finding was published in the journal Blood in 2008. Since their discovery, EpiVax has compiled substantial evidence linking Tregitopes to the activation of natural regulatory T cells. By selectively activating these natural regulatory T cells, Tregitopes can dampen unwanted immune responses. Preliminary studies carried out by EpiVax and collaborators indicate that Tregitopes may be useful for inducing tolerance to transplants, protein drugs, and blood replacement therapies, as well as for the treatment of allergies. EpiVax believes Tregitopes may explain the effectiveness of intravenous immunoglobulin G (IVIG), widely utilized as an autoimmune treatment (a $4B annual market).

The initial disease target for Tregitope therapy with the albumin-Tregitope fusion will be Type 1 diabetes (T1D). Each year, more than 13,000 young people are diagnosed with T1D. Islet replacement t
'/>"/>

SOURCE EpiVax, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. CareFusion Launches New Take-Apart Laparoscopic Scissors
2. CareFusion Reports First Half Fiscal 2013 Results
3. CareFusion Files Fiscal 2012 Form 10-K
4. B. Braun Smart Infusion Pump Technology Advances Patient Safety and Treatment Efficiency
5. Global Spinal Nonfusion Market to Grow to $1 Billion by 2017, Despite Challenges
6. Hospira and Q Core Medical Sign International Distribution Agreement for Sapphire Infusion System
7. CareFusion Launches New Preoperative Cleansing Program For In-Home Patient Use
8. Caliber and ImmunGene Launch Valor Biotherapeutics, a Joint Venture to Develop Antibody-Interferon Fusion Therapeutics to Treat Cancers
9. Practice Fusion Announces Free EMR for iPad in Beta
10. CareFusion Reports Preliminary First Quarter Fiscal 2013 Results
11. CareFusion To Report Preliminary Fiscal 2013 First Quarter Results On Nov. 8
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... March 27, 2015 RnRMarketResearch.com ... therapeutic market research report of 52 pages with ... business intelligence library. The report "Visceral ... the therapeutic development for Visceral Pain, complete with ... drug target, mechanism of action (MoA), route of ...
(Date:3/27/2015)... YORK , March 27, 2015 /PRNewswire/ ... the leading source of health information, today ... the new National Action Plan for ... President Obama emphasized the urgency and importance ... on national and global health.    ...
(Date:3/26/2015)... 26, 2015 Huntington Memorial Hospital is the ... transcatheter aortic valve replacement (TAVR), a minimally invasive replacement ... new way to replace an aortic valve without a ... machine. The procedure is performed by a ... ( Alex) Durairaj , MD, interventional cardiologist and ...
Breaking Medicine Technology:Visceral Pain Pipeline Review H1 2015 Market Research Report 2Visceral Pain Pipeline Review H1 2015 Market Research Report 3Visceral Pain Pipeline Review H1 2015 Market Research Report 4Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 2Exclusive: WebMD Interviews President Obama About Plan for Combating Antibiotic Resistance 3Huntington Memorial Hospital Performs Groundbreaking Minimally Invasive Replacement of Heart Valves 2
... N.Y. , May 27 Surgical robotic training ... of Simulated Surgical Systems, LLC (SSS) and five world renowned ... Weill Cornell Medical Center , Vattikuti Urology Institute at ... Dentistry at Robert Wood Johnson Medical School and ...
... Ankota, Inc., a Healthcare SaaS company, has launched ... enables healthcare professionals and homecare agencies to provide real-time ... and well-being.  Taking as little as 3 minutes a ... directly to families - monitoring data such as activity ...
Cached Medicine Technology:Simulated Surgical Systems, LLC Partners to Bring Simulation Advances to Surgical Training 2Simulated Surgical Systems, LLC Partners to Bring Simulation Advances to Surgical Training 3Ankota Launches Real-Time Family Communication Tool Tracking Health of Loved One 2Ankota Launches Real-Time Family Communication Tool Tracking Health of Loved One 3
(Date:3/27/2015)... Smile Brands Inc. ( http://www.smilebrands.com ), ... services to dental groups in the United States, is ... Dental office in Hendersonville, TN. , Located ... new Castle Dental office provides families with a convenient, ... comprehensive, quality dental care. Hendersonville marks the eleventh Castle ...
(Date:3/27/2015)... (PRWEB) March 27, 2015 The Florida ... Accelerate Brain Cancer Cure (ABC2), awarded $350,000 to support ... of Florida, The Scripps Research Institute and H. Lee ... support studies with a clear development path and potential ... in the near future. , The awards fund ...
(Date:3/26/2015)... Elfster.com, the top-rated Secret Santa generator, is proud to ... to its leading Secret Santa list technology. A 'bucket ... creates of things to do before one dies, made ... Nowadays many millennials are creating summer bucket lists ... "We are greatly expanding our technology to new market ...
(Date:3/26/2015)... 2015 North American Seminars launches it ... dedicated to providing information regarding OT PT continuing education ... As a leader in live hands PT ... 200 live and online continuing education courses. ... :, A Master Clinicians Approach to Advanced Concepts in ...
(Date:3/26/2015)... 26, 2015 Doctors Scott Sullivan and ... Breast Surgery (CRBS) and the St. Charles ... to announce that board certified Surgical Oncologist Dr. William ... surgeons. Ordoyne joins fellow breast surgical oncologist Alan Stolier, ... Frank DellaCroce, M.D., FACS; Scott Sullivan, M.D., FACS; Chris ...
Breaking Medicine News(10 mins):Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 2Health News:Castle Dental® Opens Its First Dental Office in Hendersonville, TN 3Health News:The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers 2Health News:The Florida Center for Brain Tumor Research and Accelerate Brain Cancer Cure Award $350,000 to Florida-Based Researchers 3Health News:Plans for Bucket List Generator - Just In Time for Summer - Announced by Elfster 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 2Health News:North American Seminars Launches Healthclick.com, a New Mobile Ready Website, Providing CME Course Information to PT, PTA, OT and ATC's 3Health News:Surgical Oncologist Joins Center for Restorative Breast Surgery and St. Charles Surgical Hospital 2Health News:Surgical Oncologist Joins Center for Restorative Breast Surgery and St. Charles Surgical Hospital 3
... on the effects of alcohol consumption on biologic mechanisms ... of a large number of intervention studies in humans. ... presented in a very clear fashion, although there was ... and polyphenols on risk factors. The ...
... German . , "Children may be a long-term investment ... Margolis from the University of Pennsylvania in Philadelphia, USA, he ... journal " Population and Development Review ". It shows a ... happiness decreases with the first and each additional child, mothers ...
... Evaluation (IHME) at the University of Washington has created ... health, and demographic data. The Global Health Data Exchange ... interface to make finding data easy. The GHDx contains ... to easily create citations some of which are ...
... one of the most aggressive tumors affecting humans. Multiple alterations ... behavior. A new study reveals new molecular insight into ... concentrates on a genetic locus -- a piece of DNA ... of a gene or DNA sequence on a chromosome -- ...
... 2011 The 2011 Sleep in America poll released today by ... in the hour before bed. It also finds that a significant ... and are searching for ways to cope. , Many Americans ... found that 43% of Americans between the ages of 13 and ...
... [Brown University] For years brain scientists have puzzled over ... seems to be present in the brain following an epileptic ... to exacerbate brain damage that follows a seizure or protect ... the molecule as squarely on the side of good: It ...
Cached Medicine News:Health News:Effects of alcohol on risk factors for cardiovascular disease 2Health News:Effects of alcohol on risk factors for cardiovascular disease 3Health News:Effects of alcohol on risk factors for cardiovascular disease 4Health News:Effects of alcohol on risk factors for cardiovascular disease 5Health News:Older parents are happier with more children 2Health News:2 proteins play key roles in Burkitt's lymphoma 2Health News:Sleepy connected Americans 2Health News:Sleepy connected Americans 3Health News:Sleepy connected Americans 4Health News:Sleepy connected Americans 5Health News:Sleepy connected Americans 6Health News:New role for an old molecule: protecting the brain from epileptic seizures 2
Each solid state catheter kit below is supplied with adapter cable(s) for Polygraf ID and a Manometric Calibrator....
Esophageal Stylet for LATITUDE® Air-Charged Catheter...
MMS Adapter Cable for LATITUDE® Air-Charged Catheter...
Solid State Manometry Catheter Accessory., ,Manometric calibrators are required for calibration of solid state catheters., ,Each type of catheter requires a unique calibrator....
Medicine Products: