Navigation Links
EpiDerm's Skin Irritation Test Fully Validated in European Union
Date:12/17/2008

Significant milestone met in development and validation of non-animal alternative test methods

ASHLAND, Mass., Dec. 17 /PRNewswire/ -- MatTek Corporation today announced that the ECVAM Scientific Advisory Committee (ESAC) endorsed the scientific validity of the Modified EpiDerm Skin Irritation Test (SIT) at its November meeting. ESAC concluded that the Modified EpiDerm SIT has sufficient accuracy and reliability for the prediction of skin irritating and non-irritating test substances.

The Updated EpiDerm SIT is a modification of the previously validated EpiDerm skin irritation method (ESAC Statement, April 2007). The major modification is an extended chemical exposure time from 15 to 60 minutes that reflects the robust barrier function of the EpiDerm model. The new exposure time provides an improved sensitivity of the in vitro EpiDerm SIT and better correlation with in vivo Draize rabbit skin irritation results.

The Modified EpiDerm SIT eliminates the need for animal testing when used to determine skin irritation potential of chemicals, including raw cosmetic materials. This development allows companies world-wide to comply with new European Union (EU) REACH legislation as well as the EU directive on the protection and welfare of animals used for experimental and other scientific purposes. This directive (EU 86/609) prohibits the use of animals in experiments if a validated alternative is available.

The Modified EpiDerm SIT will also be of great benefit to the Cosmetic Industry because testing of cosmetic raw materials in animals will be prohibited in the EU beginning March 2009 (7th Amendment of EU Cosmetic Directive).

John Sheasgreen, MatTek's President, added, "The validation of the Modified EpiDerm SIT involved multiple successful transatlantic tissue shipments from MatTek's US production facility to EU testing laboratories. The abilit
'/>"/>

SOURCE MatTek Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
2. TaiGen Biotechnology Successfully Completes Patient Recruitment for Phase II Trial of Nemonoxacin for Treatment of Adult Community Acquired Pneumonia (CAP)
3. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
4. Abbott Announces Positive One-Year Results from the Worlds First Clinical Trial of a Fully Bioabsorbable Drug Eluting Coronary Stent
5. New Data Confirms That a Selective, Fully Human Anti-VEGF Antibody Being Developed by Peregrine is as Effective as Avastin(R) in Preclinical Cancer Models
6. Medarex Announces Allowance of Investigational New Drug Applications for Wholly Owned Fully Human Anti-CD19 Antibody, MDX-1342
7. YMed, Inc. Successfully Completes First Clinical Cases With Innovative VascuTraK(TM) II PTA Dilatation Catheter
8. New Study Shows LEVITRA Successfully Treats Erectile Dysfunction (ED) in Men with Dyslipidemia, Including High Cholesterol
9. NanoBio Corporation Successfully Completes Phase 2b Study in Herpes Labialis
10. Celator(R) Pharmaceuticals Successfully Uses Nanoparticles to Administer Hydrophobic Drug Combinations
11. Novagali Pharma Successfully Enrolls First Patient in U.S. Phase I Clinical Study with CORTIJECT(R) for Diabetic Macular Edema
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... July 14, 2014 Lumin Medical LLC, a ... of PatientTrak, the leading provider of on-demand patient tracking ... Illinois to Franklin, Wis. ... which means light and our mission is to provide ... increase efficiencies and reduce costs," said James Hermann ...
(Date:7/14/2014)... Valeant Pharmaceuticals International, Inc. (NYSE: ... it has filed a premerger notification under the ... the U.S. Federal Trade Commission (FTC) relating to ... About Valeant Pharmaceuticals International, Inc. ... VRX) is a multinational specialty pharmaceutical company that ...
(Date:7/14/2014)... , July 14, 2014 Synthetic ... technology partnership with global bioengineering leader DNA2.0, ... for quick-to-market products. The integration ... machine learning optimization technologies, such as ProteinGPS™ ... process of engineering proteins in the Pareto ...
Breaking Medicine Technology:Lumin Medical Purchases PatientTrak 2Lumin Medical Purchases PatientTrak 3Valeant Pharmaceuticals Submits HSR Filing Relating To Proposed Acquisition Of Allergan 2Valeant Pharmaceuticals Submits HSR Filing Relating To Proposed Acquisition Of Allergan 3Valeant Pharmaceuticals Submits HSR Filing Relating To Proposed Acquisition Of Allergan 4Valeant Pharmaceuticals Submits HSR Filing Relating To Proposed Acquisition Of Allergan 5Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 2Pareto Biotechnologies Announces Technology Partnership With DNA2.0, Inc. 3
... 2012 Pharmatek Laboratories, Inc., a premier contract ... industry, announced that it has expanded its existing ... Automated Liquid Filling and Banding System. The addition of ... increases overall efficiency at the Phase 2 production ...
...  Swedish Covenant Hospital today announced the success of its ... Guided Surgery by Brainlab, the ultimate command and control ... option to use image guidance for a prone, occipital ... visualization in these types of procedures, and makes me ...
Cached Medicine Technology:Pharmatek Increases Liquid Filled Capsule Capacity 2Pharmatek Increases Liquid Filled Capsule Capacity 3Curve Image Guided Surgery Provides Swedish Covenant Hospital With a State-of-the-Art Command and Control Center for Information-Guided Surgery 2Curve Image Guided Surgery Provides Swedish Covenant Hospital With a State-of-the-Art Command and Control Center for Information-Guided Surgery 3
(Date:7/14/2014)... According to a recent study ... discovered a connection between women with high levels of ... Although doctors have theorized about the role stress plays ... to provide scientific support. , “Stress, if very significant, ... Larry Barmat, an OB/GYN who specializes in reproductive endocrinology ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 Jordan Valley ... of a new comprehensive cancer center set to open ... will be the only hospital west of I-15 in ... cancer services , Additionally, Jordan Valley Medical Center has ... and cancer treatment planning systems for radiation therapy, radiosurgery ...
(Date:7/14/2014)... According to a new market research report ... and Others), Devices (Power IC, Power Module & Power ... 2014 - 2020", the Power Electronics market is expected ... market is valued at $36.86 Billion and expected to ... The report also includes an in-depth analysis of the ...
(Date:7/14/2014)... Technology Institute (BTI) has entered into an agreement ... Roche, to identify novel drug candidates for the ... together BTI,s capabilities in novel antibody discovery and ... therapeutics, opening up the possibility of improved treatment ... , The collaboration makes use of BTI,s ...
(Date:7/14/2014)... Botanica Day Spa announced last month that ... at the day spa in down town Clearwater, FL ... other refreshments will be served as clients are invited ... products and great deals on spa services, including ... Dermaplaning (also known as “facial shaving”) is a simple ...
Breaking Medicine News(10 mins):Health News:Abington Health Physician Addresses Link Between Stress and Infertility 2Health News:Abington Health Physician Addresses Link Between Stress and Infertility 3Health News:Jordan Valley Medical Center Set to Break Ground with New $10 Million Cancer Center 2Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 2Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 3Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 4Health News:Power Electronics Market Estimated to Reach $36.86 Billion by 2020 at CAGR of 7.74% - New Report by MarketsandMarkets 5Health News:A*STAR partners Roche to develop new cancer therapeutics 2Health News:Botanica Day Spa to Feature Dermaplaning at Upcoming Open House 2Health News:Botanica Day Spa to Feature Dermaplaning at Upcoming Open House 3
... study on maternal malnutrition in the first trimester of ... the newborn. Dr. Tessa .J. Rosé boom of the ... occurrence of coronary heart diseases in children and correlated ... of pregnancy. They opined that maternal malnutrition during the ...
... The latest fad in the United States of America ... below 18 years, is taking the buzzword seriously.,Last year ... celebrities joining the jing bang. This pledge has been ... according to some analysts who have studied the abstinence ...
... landmark decision, has ruled that henceforth donors of sperms and ... desire so. However if the donor feels not to reveal ... ruling the identity of the donors of sperms and eggs ... with far reaching consequences. ,The communiqué released by the ...
... the United States of America, a lawyer- Peter Angelos, who ... in Maryland, has announced that he is dragging Vodafone to ... to cell phone users who are said to have developed ... This case has raised eyebrows not only because of the ...
... we have seen the newspapers carrying a news article about ... died following a high strung cricket match between India and ... Dr. Diederick E. Grobbee has revealed that there is an ... a major game. ,As compared to the number of ...
... a loved one die. More tragic is when the decision ... thin thread. Most patients of road traffic accidents, severe stokes, ... situation where they live technically only on life support systems. ... is to give consent to the medical staff attending on ...
Cached Medicine News:Health News:Brain death – How to cope with it 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: