Navigation Links
EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
Date:8/19/2007

ll growth.

EpiCept's proprietary apoptosis screening technology can efficiently identify new cancer drug candidates and molecular targets that selectively induce apoptosis in cancer cells through the use of chemical genetics and its proprietary live cell high-throughput caspase-3 screening technology. Chemical genetics is a research approach investigating the effect of small molecule drug candidates on the cellular activity of a protein, enabling researchers to determine the protein's function. Using this approach with its proprietary caspase-3 screening technology, EpiCept researchers can focus their investigation on the cellular activity of small molecule drug candidates and their relationship to apoptosis.

This combination of chemical genetics and caspase-3 screening technology allows EpiCept's researchers to discover and rapidly test the effect of small molecules on pathways and molecular targets crucial to apoptosis, and gain insights into their potential as new anticancer agents. This screening technology is particularly versatile and can be adapted for almost any cell type that can be cultured, as well as measure caspase activation inside multiple cell types (e.g., cancer cells, immune cells, or cell lines from different organ systems or genetically engineered cells). This allows researchers to find potential drug candidates that are selective for specific cancer types, which may help identify candidates that provide increased therapeutic benefit and reduced toxicity.

EpiCept has identified several families of compounds with potentially novel mechanisms that induce apoptosis in cancer cells. Several compounds from within these families have progressed to lead drug candidate status with proven pre-clinical efficacies in tumor models and identified molecular targets.

About EpiCept Corporation

EpiCept is focused on unmet needs in the treatment of pain and cancer. EpiCept has a staged portfolio of pharmaceutical product candidates wi
'/>"/>

SOURCE EpiCept Corporation

Copyright©2007 PR Newswire.

Page: 1 2 3 4 5

Related medicine technology :

1. EpiCept Corporation to Present New NP-1 Data at American Pain Society Meeting
2. Mode of Action of EpiCept-Licensed Cancer Compound Profiled at AACR
3. Corgenix Reports New Clinical Data Correlating AtherOx Technology With Vascular Disease
4. Cobalis Reports Phase III Trial Results for PreHistin in Seasonal Allergic Rhinitis
5. Cosmo Pharmaceuticals Reports Positive Preliminary Phase II/III Data with Rifamycin MMX in Infectious Diarrhea
6. Cytos Biotechnology Reports Results from Phase IIa Study with CYT003-QbG10 in Patients Suffering from Atopic Dermatitis
7. Cytokinetics Reports Additional Clinical Trials Data for Ispinesib
8. The European Myeloma Platform Reports New Survival data for Revlimid Presented at the International Myeloma Workshop in Greece
9. Cytochroma Reports Positive Phase I Clinical Data for CTA018 Injection
10. Speedel Reports Successful SPP635 Phase IIa Trial in Hypertension
11. Columbia Laboratories Reports Positive Results from Multi-dose Pharmacokinetic Study of Vaginally-administered Lidocaine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/29/2015)... South Carolina , May 29, 2015 ... have announced a collaboration designed to provide therapeutic clinical ... majority of cancer patients living in U.S. communities. ... Health to harness the power of big data and ... thousands of patients to enable ,accrual on demand, for ...
(Date:5/29/2015)... May 29, 2015  Haemonetics Corporation (NYSE: HAE ... Operating Officer, will present at the JMP Securities Life ... on June 23 rd , 2015 at 11:30am Eastern ... Davies, presentation live via webcast at: http://wsw.com/webcast/jmp27/hae ... HAE ) is a global healthcare company dedicated to ...
(Date:5/29/2015)... , May 29, 2015  World-renowned prostate surgeon and ... findings on the benefit of MR/Ultrasound Fusion-Guided Biopsy ... "Our Prostate Cancer Center at Lenox Hill Hospital ... Biopsy System in New York City . ... low risk prostate cancers. The use of an MRI makes ...
Breaking Medicine Technology:New Collaboration to Dramatically Expand Therapeutic Clinical Trial Access for Cancer Patients Across the United States 2New Collaboration to Dramatically Expand Therapeutic Clinical Trial Access for Cancer Patients Across the United States 3New Collaboration to Dramatically Expand Therapeutic Clinical Trial Access for Cancer Patients Across the United States 4MR/Ultrasound Fusion-Guided Biopsy Better Able to Detect Aggressive Prostate Cancer, New Study Says 2
...  2011 Roche (SIX: RO, ROG; OTCQX: RHHBY) announced today ... at MIT will be using the Roche LightCycler ® ... the analysis of gene expression and genetic variation, in advanced ... use the LightCycler 480 System to support several key areas ...
... YORK, April 6, 2011 The U.S. Food and Drug ... for the treatment of patients with eating disorders.   ... individuals to monitor their rate of eating and their development ... normally. Once patients learn to adapt to a normal eating ...
Cached Medicine Technology:MIT's Koch Institute to use Roche LightCycler 480 System to Help Advance Cancer Research 2FDA Clears Mandometer® for the Treatment of Eating Disorders 2
(Date:5/30/2015)... 2015 Promising clinical trial results presented ... Meeting 2015 show activity of the investigational anti-cancer agent ... against brain metastases and in another case in overall ... "I am thrilled to have been able to offer ... She didn't have any other great treatment options that ...
(Date:5/30/2015)... Michigan (PRWEB) May 30, 2015 NovaSure® ... to lighten or stop periods, without the side ... procedure can reduce or stop menstrual bleeding and works ... uterus (the part that causes the bleeding), with a ... women suffer from heavy menstrual bleeding. Many women ...
(Date:5/30/2015)... San Diego, CA (PRWEB) May 30, 2015 ... public is the lack of local healthcare options available. ... access to adequate healthcare. For those in rural areas ... those simply without health insurance or tired of paying ... announces new E-consults, connecting patients with licensed physicians via ...
(Date:5/30/2015)... New York (PRWEB) May 30, 2015 ... pay $100 million in punitive and compensatory damages ... plaintiff who suffered serious complications following implantation of ... to a verdict rendered on May 28th in ... million in compensatory damages after the jury found ...
(Date:5/30/2015)... Belton, Texas (PRWEB) May 30, 2015 ... Client Services Web Portal that gives hospices the ability ... the industry. Because of this business model, EHO has ... offer better pricing to its clients and survive among ... interface with hospice management systems three years ago, it ...
Breaking Medicine News(10 mins):Health News:ONT-380 has Stage IV HER2+ Breast Cancer Patient 'Worrying About Normal Stuff Again' 2Health News:ONT-380 has Stage IV HER2+ Breast Cancer Patient 'Worrying About Normal Stuff Again' 3Health News:Women's Excellence Now Provides NovaSure Treatment 2Health News:Online USA Doctors Brings Healthcare to the Masses with New E-Consults 2Health News:Online USA Doctors Brings Healthcare to the Masses with New E-Consults 3Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 2Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 3Health News:Boston Scientific Transvaginal Mesh Lawsuit Trial Ends With $100 Million Verdict 4
... ... in a new, or remodeled home, built between 2004, and 2008, in ... numerous air conditioning problems, combined with health issues, the Chinese Drywall Complaint ... toxic Chinese drywall being the culprit. The new major focus areas are ...
... ... selected the Atlanta-based IT support and service company to manage IT services and hosting ... ... Atlanta’s fastest growing managed IT services company, announced today that Marietta Eye Clinic ...
... ... CellTrak’s latest clients, Community Home Support Services Association (CHSSA) supports elderly ... CHSSA provides a variety of health care services during in-home client ... were recorded on paper along with older technologies, like voicemail, copies ...
... WEEKEND ADMISSION TO ICU MAY INCREASE RISK OF DEATH ... may have an increased risk of death compared with ... of Philadelphia, Philadelphia, PA, and Eastern Virginia Medical School, ... association between time of admission to the ICU and ...
... Abuse and neglect during childhood appear to be associated with ... young adults, according to a report in the June issue ... JAMA/Archives journals. Most studies of child maltreatment and later ... according to background information in the article. Doubts have been ...
... MONDAY, July 5 (HealthDay News) -- Too much time spent ... of attention problems in children and young adults, new research ... point out the ill effects of excessive screen time, whether ... a graduate student at Iowa State University, compared participants who ...
Cached Medicine News:Health News:Chinese Drywall Complaint Center Will Assist Homeowners In Tampa, Orlando, Houston, Austin & Montgomery Discover If They Have Knauf Chinese Drywall 2Health News:Chinese Drywall Complaint Center Will Assist Homeowners In Tampa, Orlando, Houston, Austin & Montgomery Discover If They Have Knauf Chinese Drywall 3Health News:Chinese Drywall Complaint Center Will Assist Homeowners In Tampa, Orlando, Houston, Austin & Montgomery Discover If They Have Knauf Chinese Drywall 4Health News:Marietta Eye Clinic Selects BlueWave Computing for IT Support and Hosting 2Health News:Marietta Eye Clinic Selects BlueWave Computing for IT Support and Hosting 3Health News:CellTrak Mobile Technology Improves Client Care in Vancouver for the Community Home Support Services Association 2Health News:CellTrak Mobile Technology Improves Client Care in Vancouver for the Community Home Support Services Association 3Health News:CellTrak Mobile Technology Improves Client Care in Vancouver for the Community Home Support Services Association 4Health News:News briefs from the July issue of Chest 2Health News:Abused children appear likely to have mental disorders as young adults 2Health News:Too Much Screen Time Can Threaten Attention Span 2Health News:Too Much Screen Time Can Threaten Attention Span 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: