Navigation Links
EpiCept Announces Successful Completion of Enrollment for Phase I Trial of EPC2407
Date:10/7/2007

ug. Results from the study will also help characterize the pharmacodynamic effects on tumor blood flow and potentially identify early signs of objective anti-tumor response as measured by CT scans, MRI or PET, in advanced cancer patients with well vascularized solid tumors.

Mr. Talley continued, "Our advancement of EPC2407 and the regulatory progress we announced earlier this month on Ceplene(TM), demonstrates the opportunities inherent in our pursuit of both early- and late-stage cancer programs, and, when combined with our pipeline of pain candidates, illustrates the long-term potential offered by our company."

About EPC2407

EPC2407 was discovered through EpiCept's Anti-cancer Screening Apoptosis Program (ASAP), a proprietary technology used to rapidly test and generate product candidates for cancer. EPC2407 has shown promising vascular targeting activity with nanomolar potencies of anti-tumor activity in pre-clinical in vitro and in vivo studies. The molecule has been shown to induce tumor cell apoptosis and selectively inhibit growth of proliferating cell lines, including multi-drug resistant cell lines. Murine models of human tumor xenografts demonstrated EPC2407 inhibits growth of established tumors of a number of different cancer types more effectively than the other VDAs tested and was synergistic when used in combination with anticancer agents, such as Cisplatin. EPC2407 is one of two VDA compounds currently in clinical trials discovered through EpiCept's ASAP technology. The second compound, Azixa(TM), is part of the EP90745 series of apoptosis inducers, which was licensed by EpiCept to Myriad Genetics, Inc. as part of an exclusive, worldwide development and commercialization agreement.

About EpiCept's ASAP Technology

Cancer cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered to destroy a cell from wi
'/>"/>

SOURCE EpiCept Corporation
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. EpiCept Corporation to Present New NP-1 Data at American Pain Society Meeting
2. Mode of Action of EpiCept-Licensed Cancer Compound Profiled at AACR
3. Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
4. Sygnis Pharma AG announces date for presentation of clinical results
5. Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis
6. Biofrontera AG Announces Clinical Study Confirms Excellent Efficacy of BF-200 ALA In Actinic Keratosis
7. YM BioSciences Announces Secondary Efficacy and Safety Findings in Randomized Phase IIB Aerolef Trial
8. BioSante Pharmaceuticals Announces New Findings for Potential Bird Flu Vaccine
9. Portola Pharmaceuticals Announces Positive Data from a Phase II Study of its Factor Xa Inhibitor at the XXI Congress of the International Society on Thrombosis and Haemostasis
10. Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
11. AVI BioPharma Partner Cook Medical Announces Completion of Patient Enrollment for APPRAISAL Phase II Clinical Trial for Treatment of Cardiovascular Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... July 14, 2014 CVS/pharmacy ® ... PLATINUM, a premium brand of 100% preservative-free vitamins ... growing family of exclusive CVS/pharmacy store brand products. ... with various benefits, including popular options such as ... women. The radiance PLATINUM line also has more premium options ...
(Date:7/14/2014)... , July 14, 2014 The legalization of ... – as well as a new economic driver – ... to sort out the right response to the will ... intoxicant. At a National Press Club ... a.m., two leading experts in the area of marijuana ...
(Date:7/14/2014)... N.Y. , July 14, 2014 We ... Surgery Center ("OACM") and the Ellicott City Ambulatory Surgery ... of Ellicott City Maryland . ... between Merritt Healthcare and 14 leading Orthopaedics, Sports Medicine, ... Facility will also accommodate the specialties of general surgery ...
Breaking Medicine Technology:CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 2CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 3NPC Newsmaker Program: Interpreting smoke signals from the marijuana skirmish line 2
(Date:7/14/2014)... (PRWEB) July 14, 2014 The ... is now offering Lumineers and porcelain veneers. ... procedures that require more preparation and greater loss of ... tooth-shaped shells to conceal visible flaws on the tooth. ... work closely with patients to ensure they offer the ...
(Date:7/14/2014)... Being physically active in middle age appears to help ... of dementia, suggest the findings from two new studies. ... at various levels, especially in midlife, is beneficial for ... said in an Alzheimer,s Association news release. "These ... More research is needed to determine the extent and ...
(Date:7/14/2014)... California (PRWEB) July 14, 2014 ... - Ultra performance liquid chromatography or UPLC ... technique of liquid chromatography that involves the ... pressure conditions to separate chromatographic compounds. This ... facilitates faster detection and analysis of chromatography ...
(Date:7/14/2014)... 2014 Many people are unhappy with ... surgery to reduce a “double chin.” A new ... need to go under the knife. Jawflex is a ... muscles, therefore tightening the skin in that area and ... is used for facial exercise, double chin elimination and ...
(Date:7/14/2014)... 14, 2014 July 14, 2014 ... in enterprise-class cloud management, governance, and compliance software ... AvePoint software will be available to customers of ... , The hosting and value-added reseller ... following AvePoint solutions to new or existing customers: ...
Breaking Medicine News(10 mins):Health News:Encino Esthetic Dental Group is Now Offering Lumineers and Porcelain Veneers 2Health News:Staying Active May Help Prevent Dementia 2Health News:Need for Faster Sample Analysis Drives Demand for UPLC, According to New Trend Report Published by Global Industry Analysts, Inc. 2Health News:Jawflex | Double Chin Exercise for Double Chin Reduction 2Health News:AvePoint Works with Rackspace to Extend Vital Management Features to Hybrid SharePoint Deployments 2Health News:AvePoint Works with Rackspace to Extend Vital Management Features to Hybrid SharePoint Deployments 3
... cardiovascular nurse and allied professional are already at the ... disease, and Professor Christi Deaton, Chairperson of the ESC ... an even greater role given the complex needs of ... to prevent cardiovascular disease," says Professor Deaton, "and we ...
... Eight projects in the Miami-Dade and Monroe Counties ... on addressing transportation and mobility options for seniors as ... winning projects were chosen based on their innovation and ... Place" services.The grants were the result of a November ...
... at 10 Rockefeller Plaza through March 31, 2009 NEW ... the Alzheimer,s Association, New York City Chapter will raise ... is due to the generosity of EHE International which ... display in its window at 10 Rockefeller Plaza.This display ...
... stores, studies find , , FRIDAY, March 6 (HealthDay News) ... are much less likely to offer healthy foods than ... live matters in terms of your diet," said study ... Hopkins Bloomberg School of Public Health in Baltimore. "If ...
... Pharmaceuticals (NYSE: VRX ) today announced that its ... 2009 at 9:00 a.m. Eastern Time, at the Hilton Hotel ... Jersey 07078. The record date for stockholders entitled to ... Valeant , Valeant Pharmaceuticals International (NYSE: VRX ) ...
... March 6 Despite the downturn in the economy, ... a healthcare-staffing agency founded 27 years ago in New ... an inevitable rebound in the economy, ANS has undertaken ... serve and more aggressively pursue clients on the Gulf ...
Cached Medicine News:Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 2Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 3Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 2Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 3Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 4Health News:EHE International Helps Alzheimer's Association, New York City Chapter to Raise Awareness About Alzheimer's Disease 2Health News:Healthy Foods Harder to Find in Poor Neighborhoods 2Health News:Healthy Foods Harder to Find in Poor Neighborhoods 3Health News:Healthy Foods Harder to Find in Poor Neighborhoods 4Health News:American Nursing Services, Inc. Expanding Eastern Presence, Opening Birmingham Office 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: