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EntreMed to Highlight ENMD-2076 Kinase Inhibitor at 2008 AACR Annual Meeting
Date:4/11/2008

wn an acceptable toxicity profile in preclinical studies without cardiovascular effects.

In addition, EntreMed scientists are scheduled for the following poster presentations:

-- "ENMD-1198 Antitumor Activity and Inhibition of HIF-1alpha, STAT3 and

NFkappaB Signaling Pathways are Dependent on Microtubule Isotype

Expression and Targeting," Monday, April 14, 2008 from 1:00 PM -

5:00 PM

-- "Combination Therapy of MKC-1 and Paclitaxel Synergistically Inhibits

Tumor Growth in the MDA-MB-231 Orthotopic Breast Cancer Tumor Model,"

Tuesday, April 15, 2008, 8:00 AM - 12:00 PM.

Dr. Bray's presentation, as well as the poster presentations, will be available on the Company's web site at http://www.entremed.com.

About EntreMed

EntreMed, Inc. is a clinical-stage pharmaceutical company developing therapeutic candidates primarily for the treatment of cancer and inflammation. MKC-1 is currently in multiple Phase 2 clinical trials for cancer. MKC-1 is an oral cell-cycle regulator with activity against the mTOR pathway. ENMD-1198, a novel antimitotic agent, and ENMD-2076, a selective kinase inhibitor, are in Phase 1 studies in advanced cancers. The Company also has an approved IND application for Panzem(R) in rheumatoid arthritis. EntreMed's goal is to develop and commercialize new compounds based on the Company's expertise in angiogenesis, cell-cycle regulation and inflammation -- processes vital to the treatment of cancer and other diseases, such as rheumatoid arthritis. Additional information about EntreMed is available on the Company's web site at http://www.entremed.com and in various filings with the Securities and Exchange Commission.

Forward Looking Statements

This release contains forward-looking statements within the meaning of the Private Securities Litigatio
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SOURCE EntreMed, Inc.
Copyright©2008 PR Newswire.
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Related medicine technology :

1. EntreMed Achieves a Key Milestone Through Initiation of ENMD-2076 Clinical Program
2. EntreMed Commences Continuous Dosing Clinical Trial For MKC-1
3. EntreMed Commences Phase 2 Study With MKC-1 in Ovarian/Endometrial Cancers
4. EntreMed to Present at The New York Society of Security Analysts Industry Conference
5. EntreMed Commences Phase 2 Study with MKC-1 in Pancreatic Cancer
6. EntreMed Shows Increased Survival With MKC-1 in Preclinical Renal Cell Cancer Model
7. EntreMed Reports Phase 1 PK and Preclinical Efficacy Results for ENMD-1198
8. EntreMed Raises $20 Million to Support Clinical Development Program
9. EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer
10. SuperGen to Highlight Oncology Pipeline Data in Multiple Presentations at the AACR Annual Meeting
11. International ACTEMRA Rheumatoid Arthritis Study Highlighted in The Lancet
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