EntreMed to Highlight ENMD-2076 Kinase Inhibitor at 2008 AACR Annu...( Oral Presentation During the New Dr...),Health

Oral Presentation During the "New Drugs on the Horizon 2" Special Session

ROCKVILLE, Md., April 11 /PRNewswire-FirstCall/ -- EntreMed, Inc. (Nasdaq: ENMD), a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and inflammatory diseases, today announced it will present preclinical data for its product candidates ENMD-2076, MKC-1, and ENMD-1198. The data will be presented by EntreMed scientists and collaborators during the American Association for Cancer Research (AACR) Annual Meeting being held April 12-16, 2008 in San Diego, California.

(Logo: http://www.newscom.com/cgi-bin/prnh/20010620/ENMDLOGO )

Mark R. Bray, Ph.D., EntreMed Vice President, Research, will give an oral presentation on the Company's selective kinase inhibitor, ENMD-2076, during the special session, "New Drugs on the Horizon 2." EntreMed will share the podium with representatives from leading pharmaceutical companies during this special session which provides early disclosure of new small molecules that are nearing or have recently advanced into clinical trials. Dr. Bray's presentation is scheduled for Sunday, April 13, 2008, at 3:15 p.m.

ENMD-2076 is selective kinase inhibitor with potent activity against Aurora A and tyrosine kinases linked to promoting cancer and inflammatory diseases. ENMD-2076 acts through multiple pathways resulting in antiproliferative activity and the inhibition of angiogenesis. ENMD-2076 has demonstrated substantial, dose-dependent efficacy as a single agent in multiple xenograft models, including tumor regression in breast, colon, and leukemia models. Importantly, ENMD-2076 is an oral agent that has sho
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