Navigation Links
Enterin Inc. Raises $12.7 Million in Series A Financing
Date:7/15/2017

PHILADELPHIA, July 15, 2017 /PRNewswire/ -- Enterin Inc., a Philadelphia-based biotechnology company developing novel compounds to treat Parkinson's disease (PD), today announced the completion of a $12.7 million Series A financing round. The financing included new investors New Ventures III, as well as the participation of existing investors.

"We are absolutely thrilled to have the support of New Ventures III and our current investors, and view the caliber of our investors as validation of the potential of our platform technology to transform the course of PD and of other neurodegenerative diseases," said Michael Zasloff, M.D. Ph.D., Founder, Chairman and CEO of Enterin. He added, "The proceeds from this financing will enable us to complete the ongoing Phase 2 study in PD, further expand our understanding of the role of alpha-synuclein (aS) in the pathology of PD and begin to explore other indications. We are very excited about working with this outstanding group of investors, and bringing their deep expertise and guidance to bear as we progress our development."

Enterin also announced that Mark Finn, Founding Partner at New Ventures III, has joined the company's Board of Directors, representing the Series A investor class.

The announcement coincides with an ongoing Phase 1/2a clinical trial, sponsored by Enterin Inc., targeting the accumulation of aS in the enteric nervous system. The trial is examining the safety, tolerability, pharmacokinetics, and pharmacodynamics of ENT-01 to relieve constipation associated with Parkinson's disease. "While the study is focused on functional improvement of the enteric nervous system, we are closely monitoring central nervous system symptoms such as sleep, REM-behavior disorder, depression, fatigue and even motor symptoms," said Denise Barbut, M.D. F.R.C.P., Co-Founder, President and Chief Medical Officer of Enterin. She added, "The drug has the potential to slow the progression of PD and of other neurodegenerative disorders in which dysfunction of the enteric nervous system plays a part." Details of the RASMET study can be found on clinicaltrials.gov. ENT-01 is an oral drug that contains a synthetic derivative of squalamine.

Research recently published by Dr. Zasloff and collaborators demonstrated that squalamine both reduced the formation of toxic aS clumps and their toxicity in animal models of Parkinson's disease. Most recently, the founders and their colleagues demonstrated that aS is induced in response to viral gastrointestinal infections in children and that it brings in the immune system to help defend the nervous system and the gut. Links to the articles and to related press coverage can be found at the Enterin website.

About Enterin Inc.

Enterin Inc. is the first company in the world to develop a novel drug that repairs the dysfunctional gut-brain axis in patients with neurodegenerative disease. Enterin Inc. is pioneering the medical community's understanding of the link between infections, dysfunction of the enteric nervous system of the gut, and the early onset and chronic progression of neurodegenerative disease. The lead compound, ENT-01, displaces membrane-bound alpha-synuclein (aS) aggregates from nerve cells in the enteric nervous system and improves neural signaling between the gut and the brain in preclinical models of Parkinson's disease. In the gut, this results in improved mobility. Enterin Inc. is now progressing ENT-01 through clinical trials aimed at reversing the constipation of Parkinson's disease. For more information, please visit www.enterininc.com.

 About New Ventures III

New Ventures is a leading healthcare venture capital firm focusing on innovating and disruptive areas in life sciences and healthcare. New Ventures invests globally throughout the healthcare industry, from new businesses to royalties on developed drugs. The New Ventures team is a group of co-founders, entrepreneurial operators, and investors with over 100 years of experience. The team has a history of collaborating on various projects together building companies and investing in life sciences, healthcare and agriculture. Our team understands the science and technology breakthroughs needed to achieve radical change that improves the human condition and simultaneously creates value for our investors. To learn more about New Ventures, please visit www.newventuresfunds.com.

Contact

Enterin Inc.
info@enterininc.com

 

View original content with multimedia:http://www.prnewswire.com/news-releases/enterin-inc-raises-127-million-in-series-a-financing-300488803.html


'/>"/>
SOURCE Enterin Inc.
Copyright©2017 PR Newswire.
All rights reserved


Related medicine technology :

1. Enterins RASMET Study Enrolls First Patient With Parkinsons Disease
2. Spinal Muscular Atrophy Program Advances with Additional Product Candidate Entering Clinical Development
3. da Vinci Lawsuit Settlement News Update: Intuitive in Settlement Talks with Select Private Claims Prior to Entering Mass Tort Litigation, Says Lawsuitsettlementnews.com Website
4. Among New Agents Entering the Unipolar Depression Market Over the Next Decade, Lundbeck/Takeda Pharmaceuticals Brintellix Has Blockbuster Potential
5. Hill-Rom Exceeds Guidance With Strong Fiscal Second Quarter Financial Results And Raises 2017 Full-Year Outlook
6. ZappRx raises $25 million in Series B funding led by Qiming US Healthcare Fund with Participation from SR One and GV
7. Twist Bioscience Raises $33 Million
8. Cardiva Medical Raises $30 Million
9. Medin Successfully Recapitalizes and Raises New Capital With Financial Partner
10. SCPC Praises Collins/Loebsack Bill Boosting Generic Prescription Drug Payment Transparency
11. Nido Surgical Raises $1.3M Series A Led By Broadview Ventures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/10/2017)... Oct. 10, 2017   West Pharmaceutical Services, Inc. ... for injectable drug administration, today shared the results of ... for improving the intradermal administration of polio vaccines. The ... Summit in May 2017 by Dr. Ondrej Mach ... World Health Organization (WHO), and recently published in the ...
(Date:10/4/2017)...  South Korean-based healthcare product Development Company I.M. Lab ... Kickstarter. The device will educate the user about ,proper, ... efficiency compared to the dated and pricey CPR training ... of the compression for a more informed CPR training. ... raise $5,000. cprCUBE ...
(Date:10/2/2017)... FLINT, Mich. , Oct. 2, 2017 ... acquired 8th Day Software and Consulting, LLC , ... 8th Day Software, based in Tennessee ... Management LLC. 8th Day expands EnvoyHealth,s service offerings for ... product development. "In ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of sub-acute ... of a disaster drill on October 3rd. , Apple Rehab participated with the Shelton ... well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The LTC-MAP ...
(Date:10/13/2017)... Abilene, Texas (PRWEB) , ... October 13, 2017 , ... ... publication this week that explains one of the most popular and least understood books ... seems like cryptic and puzzling descriptions that have baffled scholars for centuries. Many have ...
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare ... program management, will showcase a range of technology and learning solutions at the ... Convention and Expo to be held October 14–18, 2017 at the Mandalay Bay ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... Leading pediatric ... peers in Washington, D.C., for the 49th Congress of the International Society of ... Vice President of the Center for Cancer and Blood Disorders at Children’s ...
Breaking Medicine News(10 mins):