Navigation Links
Endpoints - Clinical Trials in Respiratory Diseases - Pulmonary Function Tests, Biomarkers and Quality of Life Questionnaires All Play Prominent Roles
Date:8/27/2012

d effective strategies by clinical phase wise endpoint analysis of clinical trials. This can help in reducing the drug's time to market.

- Exploit strategies for designing of clinical trials by identifying the advantages and disadvantages involved with the use of specific endpoints.

1 Table of Contents1 Table of Contents 51.1 List of Tables 81.2 List of Figures 102 Introduction 133 Clinical Trials Endpoints in Respiratory Diseases - An Overview 143.1 Introduction 143.2 Types of Endpoints 143.2.1 Primary Endpoints 143.2.2 Secondary Endpoints 143.2.3 Surrogate Endpoints 154 Endpoints - Clinical Trials in Asthma - Marketed and Pipeline Products Assessment 164.1 Introduction 164.2 Primary Endpoints Used in Asthma Clinical Trials 204.2.1 Pulmonary Function Tests: 204.2.2 Vital Signs and Physical Activity 204.2.3 Biomarkers 204.2.4 Serious Adverse Events 204.3 Secondary Endpoints Used in Asthma Clinical Trials 214.3.1 Pharmacokinetics and Pharmacodynamics 214.3.2 Quality of Life Scores 214.3.3 Clinical Laboratory Tests – Biochemistry and Serum Hematology 214.3.4 Use of Rescue Medication 214.4 Asthma Therapeutics – Major Marketed Drugs 214.4.1 Singulair (Montekeulast Sodium) 214.4.2 Accolate Accoleit, Vanticon (Zafirlukast) 224.4.3 Zyflo (Zileuton) 234.4.4 Foradil (Formoterol Fumarate Inhalation Powder) 244.4.5 Symbicort (budesonide/formoterol fumarate dihydrate inhalation aerosol) 254.4.6 Xolair (Omalizumab) 274.4.7 Serevent Diskus (Salmaterol Xinafoate Inhalation Powder) 284.4.8 Advair Diskus (Fluticasone Propionate and Salmeterol Inhalation Powder) 294.5 Asthma Therapeutics – Promising Drugs under Clinical Development 304.5.1 Daxas (Roflumilast) (Daxas, APTA 2217, B9302-107, BY 217, BYK 20869) 304.6 Phase III Clinical Trial Analysis 314.6.1 Completed Trial Analysis 314.6.2 Active Trial Analysis 354.6.3 Terminated Trial Analysis 394.7 Phase II Clinical Trial Analysis 414.7.1 Completed Trial Analysis 414.7.2 Active Trial Analysis 454.7.3 Te
'/>"/>

SOURCE Reportlinker
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17

Related medicine technology :

1. Alder Biopharmaceuticals Receives $3.5 Million Milestone Payment from Bristol-Myers Squibb for Initiation of Phase 2 Clinical Trial of ALD518/BMS-945429 in Crohns Disease
2. As Tuberculosis Grows More Difficult to Control, Vaccine Candidate to Prevent Disease Enters Clinical Testing
3. Millennium Laboratories Announces Landmark Pharmacogenetics Clinical Outcomes Study
4. VolitionRX to Begin Prospective Clinical Trial in Colon Cancer
5. Indegene Introduces TrialPedia 2.0 with Advantage Insights, Making It the Most Comprehensive Clinical Trial Analytics and Decision Support Platform for the Pharma Industry
6. Imprimis Pharmaceuticals Signs Agreement With DPT Labs For Clinical Supplies In Advance Of Planned Phase 3 Studies For Its Ketoprofen-Based Topical Anti-Inflammatory Drug
7. AbGenomics International Obtains FDA Agreement on Its Phase 2 Clinical Trial Plans
8. Nectid Announces Initiation Of Clinical Development Of Autism And Pain Drugs
9. Meritage Pharma Initiates Clinical Trial of Oral Budesonide Suspension for Adolescent and Adult Patients with Eosinophilic Esophagitis
10. MultiCell Technologies Updates Preclinical Results for MCT-465 and MCT-485 in Primary Liver Cancer in vitro Models
11. Omeros Announces Completion of Enrollment in OMS103HP Phase 3 Clinical Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... , Sept. 30, 2014  Georgia-Pacific Professional is ... and tissue for a wide range of away ... its product lines in healthcare, including hospitals, long-term ... Professional is introducing its healthcare products and solutions ... understands the importance of infection control in the ...
(Date:9/30/2014)... BURLINGTON, Mass. , Sept. 30, 2014 /PRNewswire/ ... of U.S. patient-level claims data, anemic chronic kidney ... with their erythropoiesis-stimulating agent (ESA) medication. In addition, ... Janssen,s Procrit. Other key findings ... in Nephrology: An Analysis of Erythropoiesis Stimulating Agents ...
(Date:9/30/2014)... 30, 2014   Acutus Medical, Inc. ... real-time 3D Cardiac Chamber Imaging and Dipole Density Mapping ... or sustain complex cardiac arrhythmias, including atrial fibrillation, announced ... developing its imaging/mapping system as well as bring to ... Acutus Medical to complete work on the AcQMap TM ...
Breaking Medicine Technology:Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 2Georgia-Pacific Professional Brings Its Success in Medical Solutions to the Dental Community 3Persistency is Low for Late-Stage Anemic CKD Non-Dialysis Patients Treated with Erythropoiesis-Stimulating Agents 2Persistency is Low for Late-Stage Anemic CKD Non-Dialysis Patients Treated with Erythropoiesis-Stimulating Agents 3Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 2Acutus Medical, Inc. Completes Additional $26.2M Series B Financing to Fund Portfolio Expansion 3
... Inc. (OTCBB: PLCSF), a company focused on innovative medical ... REMEDIAL II investigator-sponsored clinical trial of RenalGuard® ... , a peer-reviewed journal of the American Heart Association ... in the September 2011 issue of the publication.  The ...
... A national analysis conducted by Sperling,s BestPlaces and ... Columbus, Ohio, as one of the nation,s Hypertension ... factors and complications. The identification of the Hypertension ... hypertension awareness program called Commit to Control ...
Cached Medicine Technology:REMEDIAL II Trial of PLC's RenalGuard® Article Published in Circulation 2REMEDIAL II Trial of PLC's RenalGuard® Article Published in Circulation 3REMEDIAL II Trial of PLC's RenalGuard® Article Published in Circulation 4Columbus Included in Analysis of Top Hypertension Hot Spots in the United States 2Columbus Included in Analysis of Top Hypertension Hot Spots in the United States 3Columbus Included in Analysis of Top Hypertension Hot Spots in the United States 4
(Date:9/30/2014)... TUESDAY, Sept. 30, 2014 (HealthDay News) -- Children conceived either ... the birth of a sibling could be at increased risk ... study,s lead author and an outside expert agree that the ... in autism. "Most importantly, it is important that parents ... even when pregnancies are close together or far apart," said ...
(Date:9/30/2014)... potential for doctors to measure damaging "brain tsunamis" ... moved a step closer to reality, thanks to ... Neuroscience Institute. , The research team, led by ... department of neurosurgery at the UC College of ... spread through an injured brain like tsunami wavescan ...
(Date:9/30/2014)... cancer is the leading cause of cancer death in ... so many medical professionals encourage women to get mammograms, ... a minority of suspicious mammograms actually leads to a ... worry for women and their familiesnot to mention the ... and biopsies. , Recently, a different type of ...
(Date:9/30/2014)... in 2003 to slow the spiraling costs of drugs ... patients has had no meaningful impact on cancer chemotherapy ... Journal of Clinical Oncology published online today. ... treat colorectal and lung cancers, and did not find ... following the implementation of the recent Medicare law in ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 Integrated ... wellness, is opening another new medical specialty practice through ... IMA Cardiology will be located within the company’s ... Abbud and Dr. Isaac Tawfik of American Heart Center, ... The new practice will offer Integrated Medicine Alliance patients ...
Breaking Medicine News(10 mins):Health News:Spacing Between Sibling Births Tied to Autism Risk in Study 2Health News:Researchers show EEG's potential to reveal depolarizations following TBI 2Health News:Researchers show EEG's potential to reveal depolarizations following TBI 3Health News:'Virtual breast' could improve cancer detection 2Health News:Landmark Medicare law had little impact on reducing chemotherapy cost 2Health News:Integrated Medicine Alliance Announces New Cardiology Practice 2
... the general U.S. population, people who are uninsured are ... as those with insurance, according to systematic review of ... Group. They also found that once admitted to the ... to have invasive procedures or pulmonary artery catheterizations and ...
... papers just published in two leading scholarly journals, LSU sociology ... mortality rates are on average substantially lower in communities with ... fellow in LSU,s Office of Research and Economic Development, has ... the last 10 years, and these studies extend the research ...
... ... , ... April 28, 2010 -- According to a survey conducted by Hear the World, a global ... not only result in gradual hearing loss, but also stress, aggression or insomnia in 73 ...
... still exposed to dangerous levels of smog and soot , ... efforts to reduce air pollution in the United States ... and Midwest, 175 million people are still exposed to dangerous ... The survey, from the American Lung Association, credits a considerable ...
... ... of the unique bond between adults and their moms - has been released publicly on YouTube ... ... for Mothers - I Honor You " by bestselling author Brian Vaszily has been released on ...
... Mother,s Day is ... clothing and get her a therapeutic massage instead. Massage Envy is offering great ... ... care. Get the best present for Mother’s Day 2010, a Massage Envy gift card. Massage ...
Cached Medicine News:Health News:ATS systematic review: Critical care outcomes tied to insurance status 2Health News:ATS systematic review: Critical care outcomes tied to insurance status 3Health News:Civic engagement imperative for reduction of violence and improved public health 2Health News:Hear the World Survey Reveals Growing Noise Pollution Affecting both Physical and Mental Health 2Health News:Hear the World Survey Reveals Growing Noise Pollution Affecting both Physical and Mental Health 3Health News:Hear the World Survey Reveals Growing Noise Pollution Affecting both Physical and Mental Health 4Health News:Hear the World Survey Reveals Growing Noise Pollution Affecting both Physical and Mental Health 5Health News:Air Quality Better in Northeast, Midwest 2Health News:Air Quality Better in Northeast, Midwest 3Health News:Air Quality Better in Northeast, Midwest 4Health News:Inspirational Short Video for Adults Who Celebrate Their Mothers Called "A Poem for Mothers" Released on YouTube 2Health News:Inspirational Short Video for Adults Who Celebrate Their Mothers Called "A Poem for Mothers" Released on YouTube 3Health News:Forget the Flowers for Mother's Day This Year -- Get Her a Massage Instead 2
... 2 60-ms bursts of 50 Hz separated by .75 ... Tetanus: 50 Hz (50 pulses/s) or 100 Hz (100 ... Output Current: Adjustable from 0-70 mA , Stimulus ... Battery LED (green) indicates that the units on; it ...
Anesthesia Associates Nerve Stimulator Model AA 1050...
... newest peripheral nerve stimulator from B. Braun Medical. ... providing advanced digital technology. , ,Your ability ... allows the localization of practically all mixed nerves ... ,An additional optional component for the HNS11 is ...
... original MS-III design the new ... keypad and battery ... MS-IV peripheral nerve stimulator can ... in operating room, post anesthesia ...
Medicine Products: