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Encouraging Clinical Data From Multicenter Phase 1/2 Trial On Actinium's Actimab-A Presented At American Society Of Hematology Annual Meeting
Date:12/9/2013

NEW YORK, Dec. 9, 2013 /PRNewswire/ -- Actinium Pharmaceuticals, Inc. (OTCQB: ATNM.OB) ("Actinium" or "the Company"), a biopharmaceutical Company developing innovative targeted payload immunotherapeutics for the treatment of advanced cancers, were presented in a poster session on Saturday, December 7, 2013 at the American Society of Hematology's (ASH) 55th Annual Meeting and Exposition in New Orleans.  Data demonstrated antileukemic effect in 67% of evaluable patients and 47% of patients treated across all dose levels.  Participants in the trial were newly diagnosed acute myeloid leukemia (AML) patients with poor prognostic factors unable or unwilling to receive standard chemotherapy.

Abstract presented at this year's ASH meeting reported the initial data from this study demonstrating that administration of Actimab-A (monoclonal antibody HuM195 labeled with actinium 225) in fractionated doses is feasible, safe and has antileukemic activity.

Abstract Information

The Actimab-A abstract information is as follows:

Session: 615. Acute Myeloid Leukemia: Therapy, excluding Transplantation: Poster I

Abstract #1460:  "Phase I Trial Of The Targeted Alpha-Particle Nano-Generator Actinium-225 (225Ac)-Lintuzumab (Anti-CD33) In Combination With Low-Dose Cytarabine (LDAC) For Older Patients With Untreated Acute Myeloid Leukemia (AML)"

An abstract summarizing the data is published on the ASH website at (https://ash.confex.com/ash/2013/webprogram/Paper63558.html)

About Actimab-A™

Actimab-A is a drug candidate construct made using Actinium Pharmaceuticals' proprietary patented technology for arming monoclonal antibodies with alpha emitters actinium 225 and bismuth 213.  Antibodies are used as high precision delivery systems that bring powerful alpha emitters into or immediately next to tar
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SOURCE Actinium Pharmaceuticals, Inc.
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