Navigation Links
Enbrel Will Remain Decision Resources' Clinical Gold Standard Through 2018 for the Treatment of Rheumatoid Arthritis

WALTHAM, Mass., Jan. 12 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that Amgen/Pfizer/Takeda's Enbrel will retain Decision Resources' proprietary clinical gold standard status for the treatment of rheumatoid arthritis through 2018. Although Centocor Ortho Biotech/Merck/Mitsubishi Tanabe/Janssen's Simponi offers delivery advantages over Enbrel in formulation (potentially offered in both subcutaneous and intravenous formulations) and dosing frequency (once monthly compared with once or twice weekly for Enbrel), neither Simponi nor any other rheumatoid arthritis biologic have the same effect as Enbrel in inhibiting/slowing structural damage progression.

The new report entitled Rheumatoid Arthritis: Opportunity Awaits Therapies that Meet Physicians' Efficacy Expectations in TNF-α Inhibitor-Refractory Patients also finds that rheumatologists are unwilling to compromise on efficacy or convenient delivery for a disease-modifying drug with a novel mechanism of action for patients who are refractory to tumor necrosis factor alpha (TNF-alpha) inhibitors, even if such an agent entered the market at a lower price point than leading biologics. Surveyed U.S. rheumatologists stated that such a drug (that doesn't compromise on efficacy) could be prescribed to 63 percent of eligible U.S. patients. Surveyed European rheumatologists indicated that such an agent could be prescribed to 75 percent of eligible European patients.

"Because we believe the TNF-alpha inhibitors will remain the most prescribed treatments for patients who have failed or lost response to conventional disease-modifying antirheumatic drugs, we profiled the opportunity for an agent in the TNF-alpha inhibitor-refractory population in our study. High price, intravenous delivery route and the potential for harmful side-effects are all drawbacks to current biologic agents used to treat TNF-alpha inhibitor-refractory patients. However, given a drug with incremental safety, delivery and even cost advantages, physicians are still unwilling to compromise on efficacy," stated Decision Resources Analyst Kyle Crowell.


Members of the media are welcome to attend our upcoming webinar entitled Can Your Drug Gain An Edge in the TNF-Alpha Refractory Patient Segment of the Rheumatoid Arthritis Market? Exploring Drug Attributes Needed to Maximize Patient Share. This webinar will be held on Wednesday, January 27, 2010 at 10 a.m. U.S. Eastern Time. For more information, please contact Gisselle Morales at 781-296-2691 or by email at

About the Report

Rheumatoid Arthritis: Opportunity Awaits Therapies that Meet Physicians' Efficacy Expectations in TNF-α Inhibitor-Refractory Patients is a DecisionBase 2010 report. DecisionBase 2010 is a decision-support tool that provides in-depth analysis of unmet need, physician expectations of new therapies and commercial dynamics to help pharmaceutical companies optimize their investments in drug development. 

About Decision Resources

Decision Resources ( is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources, Inc. company.

About Decision Resources, Inc.

Decision Resources, Inc. is a cohesive portfolio of companies that offers best-in-class, high-value information and insights on important sectors of the healthcare industry. Clients rely on this analysis and data to make informed decisions. Please visit Decision Resources, Inc. at

All company, brand or product names contained in this document may be trademarks or

registered trademarks of their respective holders.

SOURCE Decision Resources



SOURCE Decision Resources
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. CHMP Recommends Approval of New Indication for Enbrel(R) as Treatment for Severe Psoriasis in Paediatric Patients
2. Current and Emerging Drugs Have No Advantage Over Enbrel in Inhibiting/Slowing the Progression of Rheumatoid Arthritis
3. Senate Rejects Bulk Imports of Medicine from Canada, but Personal Importation Remains a Popular Option for U.S. Citizens
4. Acute Ischemic Stroke Drug Market Will Remain Relatively Flat, Increasing From $360 Million in 2008 to $450 Million in 2018
5. Shire Completes Submission of NDA for Velaglucerase Alfa for Type 1 Gaucher Disease and Reports Positive Results for Remaining Two Phase III Trials
6. Swine Flu (H1N1) Infectivity to Increase Markedly and Lethality to Remain Low According to Latest Replikin* Peptide Genomic Data
7. U.S. Naval Medical Research Center Proposed RESUS Clinical Trial in Trauma Patients Remains on FDA Hold
8. For Old or Young Dialysis Patients, AV Fistulas Remain Pure Gold
9. Cardiac Disease in Women Remains Untreated for Decades
10. Quality Colonoscopy Exam Remains Best Strategy for Detection of Polyps and Cancers According to Experts From the American College of Gastroenterology
11. New Data Show That Herceptin, Xeloda and Avastin Help Patients With Early and Advanced Breast Cancer Live Longer or Remain Disease Free for Longer
Post Your Comments:
(Date:6/24/2016)... 24, 2016 According to a ... (Standard Pen Needles, Safety Pen Needles), Needle Length (4mm, ... Hormone), Mode of Purchase (Retail, Non-Retail) - Trends & ... studies the market for the forecast period of 2016 ... 2.81 Billion by 2021 from USD 1.65 Billion in ...
(Date:6/24/2016)... , June 24, 2016 VolitionRx ... of Dr. Edward Futcher to the ... effective June 23, 2016.Dr. Futcher was also appointed ... Governance Committees.  As a non-executive member of the ... and strategic counsel to VolitionRx in connection with ...
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... ... First Choice Emergency Room , the largest network of independent freestanding ... of its new Mesquite-Samuell Farm facility. , “We are pleased to announce Dr. ... James M. Muzzarelli, Executive Medical Director of First Choice Emergency Room. , Dr. ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... recover from injury. Recently, he has implemented orthobiologic procedures as a method for ... is one of the first doctors to perform the treatment. Orthobiologics are substances ...
(Date:6/25/2016)... , ... June 25, 2016 , ... Conventional wisdom preaches ... success. In terms of the latter, setting the bar too high can result in ... than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Those who ... with these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, ... Marne, Michigan, has released tools for healthy coping following a traumatic event. , Trauma ...
(Date:6/24/2016)... ... , ... Marcy was in a crisis. Her son James, eight, was out of control. Prone ... physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. “If ... at my other children and say he was going to kill them. If we ...
Breaking Medicine News(10 mins):