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Enanta Reports New Macrolide-Related Drug Class, Bicyclolides, to Combat Hospital and Community Acquired Superbug Infections, Including MRSA
Date:4/10/2008

els of the Bicyclolides. The convenience of oral administration and the safety profile of macrolides as a class represent patient and pharmacoeconomic benefits that could be potentially quite significant, making this program a worthwhile endeavor."

About Enanta's Bicyclolide research program

Bicyclolides posses a reengineered back-bone structure of traditional macrolides, whose benefits include the potential for oral and intravenous administration and limited side-effects. The discovery of Bicyclolides' effectiveness against MRSA and VRE infections is part of Enanta's broad antibiotic research program. Enanta has applied several research strategies to develop these new classes of antibiotics, including innovative medicinal chemistry approaches to create novel and proprietary chemical structures. Enanta has applied its chemistry approach to create promising product pipelines and a vast intellectual property estate.

About MRSA

More than 130,000 people each year need hospital care for MRSA, according to the Centers for Disease Control and Prevention. Staphylococcus aureus is a bacterium that can live harmlessly on human skin and is found in the nose of 20 to 40 percent of healthy individuals, but can sometimes cause infections when exposed to broken skin. MRSA is a particular type of the bacteria that has developed resistance to many antibiotics, including methicillin, making it difficult to treat. Currently, the antibiotic drugs typically administered to MRSA patients are intravenous. This method is expensive and inconvenient, especially for those who acquired the infection in the community and must seek hospital treatment for lengthy intravenous treatment.

About Enanta

Enanta Pharmaceuticals is a research and development company that uses its novel chemistry approach and drug discovery capabilities to create best in class small molecule drugs in the anti-infective field. At the heart of Enanta is its commitment to innovative
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SOURCE Enanta Pharmaceuticals
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