Navigation Links
Enanta Reports New Macrolide-Related Drug Class, Bicyclolides, to Combat Hospital and Community Acquired Superbug Infections, Including MRSA
Date:4/10/2008

Data Presented at the 10th Annual Superbugs and Superdrugs Conference on

Antibacterials

WATERTOWN, Mass., April 10 /PRNewswire/ -- Enanta Pharmaceuticals, a leader in the development of small molecule anti-infective drugs, today announced the presentation of their breakthrough research program to evaluate a new macrolide-related drug class, Bicyclolides, in the treatment of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and other gram-positive infection pathogens. Enanta's Bicyclolides have also demonstrated strong activity against MRSA strains resistant to vancomycin, Zyvox(R) (linezolid), and CUBICIN(R) (daptomycin).

The oral presentation, "New Bicyclolides Active Against MRSA and VRE," was presented today during the 10th Annual Superbugs and Superdrugs Conference in London, England.

"Previously, MRSA infection was a problem mainly for patients treated in hospitals," said Robert Moellering, M.D., a professor of medicine at Harvard Medical School and Beth Israel Deaconess Medical Center. "Now we're seeing MRSA in the general community, creating a tremendous need for a new class of antibiotics with improved safety profile and more convenient administration for use within both hospital as well as community settings. The growing problem of bacterial resistance to many existing drugs also necessitates the development of new classes of compounds to fight the battle."

"Pre-clinical research on these new Bicyclolide compounds revealed activity against MRSA and VRE, even against highly drug-resistant MRSA strains. This was an unexpected finding, because traditional macrolides do not work against these bacteria," explained Yat Sun Or, Ph.D., Senior Vice President of Research and Development at Enanta. "These results are also very exciting, because we have observed activity as good as intravenously-administered vancomycin or Zyvox(R) with oral once-a-day dosing lev
'/>"/>

SOURCE Enanta Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. MAP Pharmaceuticals Reports Positive Results From Phase 2a Clinical Trial of Combination Therapy in Adult Asthmatics
2. Catalyst Pharmaceutical Partners Reports Fourth Quarter and Year-End 2007 Financial Results
3. Rexinoid Developed by NuRx Pharmaceuticals Shows Promise in Prevention, Treatment of Lung, Breast Cancer, Paper in Clinical Cancer Research Reports
4. MAP Pharmaceuticals Reports Positive Results From Comparative Pharmacokinetic Trial for its Pediatric Asthma Product Candidate
5. New Study Reports That Physical Therapy Treatment Resolves Symptoms of Urinary Incontinence in Women
6. Ardea Biosciences Reports Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating up to 2.0 Log Reduction in Plasma Viral Load
7. Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status
8. NPS Reports Successful GATTEX(TM) Extension Study
9. New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
10. Novavax Reports Fourth Quarter and 2007 Year-End Financial Results
11. GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/14/2009)... According to Millennium Research Group (MRG), ... increased use of safety devices for small-bore connectors ... key driver of the enteral feeding device markets ... US and European Markets for Enteral Feeding ... set segment will experience the greatest impact from ...
(Date:12/14/2009)... SUNNYVALE, Calif., Dec. 14 Accuray Incorporated ... the field of radiosurgery, announced today that the ... be installed at the University Hospital of Liege. ... 1,000-bed hospital, is one of the largest hospitals ... inhabitants. ,, "With a full range of ...
(Date:12/14/2009)... Inc. (Nasdaq: MYL ) today announced that ... Index Dec. 21. Mylan,s common shares will also ... Chairman and CEO Robert J. Coury said: "We ... followed index of leading companies. This development marks ... the rapid growth and strong potential of our ...
Breaking Medicine Technology:Enteral Feeding Device Market To Generate More Than $700 Million in the US & Europe by 2014 2Enteral Feeding Device Market To Generate More Than $700 Million in the US & Europe by 2014 3First CyberKnife in Belgium to be Installed at Leading University Hospital 2First CyberKnife in Belgium to be Installed at Leading University Hospital 3Mylan Added to NASDAQ-100 Index 2North Atlantic fish populations shifting as ocean temperatures warm 10600 1North Atlantic fish populations shifting as ocean temperatures warm 10600 2North Atlantic fish populations shifting as ocean temperatures warm 10600 3Researchers identify the 3 killer indicators that are even worse than high cholesterol 60529 1Researchers identify the 3 killer indicators that are even worse than high cholesterol 60529 2Developmental drug may help bone fractures heal after radiation exposure 60527 1
... Independent Study by the National Cancer Institute Revealed Divine No. ... in Inhibiting Viruses that Cause ... and Anal Cancers in vitro, ORLANDO, Fla., Jan. 22 ... that promises to,revolutionize the market. The National Cancer Institute,s Laboratory ...
... Jan. 22 Protalix,BioTherapeutics, Inc. (Amex: PLX ... concept results in an animal study conducted as ... is being conducted under the agreement the Company ... the technology transfer,arm of the Hebrew University of ...
Other Medicine Technology:Divine Corporation's Personal Lubricants Shown to Block Cancer-causing Viruses in a Study by the National Cancer Institute 2Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study 2Protalix BioTherapeutics Extends Research Agreement With Yissum Based on Promising Acetylcholinesterase Program Results in Animal Study 3
(Date:12/14/2009)... may also offer some protection, study finds, , , MONDAY, ... people who can,t start their morning without a cup ... decrease the risk of developing type 2 diabetes. ... also found the more coffee you drink, the lower ... associated with a 7 percent reduction in the risk ...
(Date:12/14/2009)... for asthma, COPD, researchers say , , MONDAY, Dec. 14 ... that influence lung function, a finding that may help ... international team of researchers compared lung function with genetic ... the human genome in more than 20,000 people of ... common genetic variants associated with alterations in lung function. ...
(Date:12/14/2009)... United Nations Foundation’s Nothing But Nets tipped off a promotion--Send a ... anti-malaria bed nets to refugees in 11 African countries. The effort ... through January 31, 2010. , ... New ... Association (NBA) and the United Nations Foundation’s Nothing But Nets tipped ...
(Date:12/14/2009)... Hospital records show consistent rate of lacerations, accidental ... ,, BOSTON, Dec. 14 A new ... Medicine has found that holiday decorations, particularly glass ... consider during the season. A review of records ... five ornament-related injuries per year, more than half ...
(Date:12/14/2009)... asked to approve naming the women,s hospital -- located ... complex -- after Ted and Jane Von Voigtlander ... University of Michigan Health System has received a $15 ... Foundation, the largest gift ever made to the Health ... of a new women,s hospital. ,, The gift is ...
Breaking Medicine News(10 mins):Health News:Coffee, Tea Might Stave Off Diabetes 2Health News:Coffee, Tea Might Stave Off Diabetes 3Health News:NBA Cares and United Nations Foundation Partner to Launch Send A Net. Save A Life. See A Game. Presented By HP 2Health News:NBA Cares and United Nations Foundation Partner to Launch Send A Net. Save A Life. See A Game. Presented By HP 3Health News:NBA Cares and United Nations Foundation Partner to Launch Send A Net. Save A Life. See A Game. Presented By HP 4Health News:Parents: Be Mindful of Hazardous Holiday Ornaments 2Health News:Parents: Be Mindful of Hazardous Holiday Ornaments 3Health News:University of Michigan Health System Receives $15 Million Gift, The Largest Ever for Women's Health 2Health News:University of Michigan Health System Receives $15 Million Gift, The Largest Ever for Women's Health 3Health News:University of Michigan Health System Receives $15 Million Gift, The Largest Ever for Women's Health 4Health News:University of Michigan Health System Receives $15 Million Gift, The Largest Ever for Women's Health 5
... MDThe United States places last among 19 countries when it ... to timely and effective health care, according to new research ... issue of Health Affairs. While other nations dramatically improved these ... , If the U.S. had performed as well as the ...
... have found that Medicare spending across the country varies greatly. ... be the same no matter which region a person lives ... there is no value to the excess costs in high-spending ... cancer as a model suggests this is not correct. ...
... Ill., Jan. 7 When it comes to graduate ... of Nursing in,Peoria sets the pace for others in ... to offer a Doctorate of Nursing Practice (DNP) Program,in ... the only,joint degree -- Master,s in Nursing and Master,s ...
... 7 Zimmer Holdings, Inc.,(NYSE: ZMH ; SWX: ... fourth quarter and full-year 2007 sales and earnings conference,call ... January 29, 2008,at 8:00 a.m. Eastern Time. A news ... available at 7:00 a.m. the morning of the,conference call., ...
... Congress to allow price,negotiation, WASHINGTON, Jan. 7 ... plans continue to hike the cost of,prescriptions for seniors, ... drugs, between the month of December and January alone. ... five drugs by more than,$500 during that time., ...
... a New Department Designed to Establish Manufacturer Advertising through the ... ... Pharmacy., TALLAHASSEE, Fla., Jan. 7 Deborah Faucette, R.Ph. has,been named ... Sales and Marketing., Deb will lead a new department that, according ...
Other Medicine News:Health News:New study: US ranks last among other industrialized nations on preventable deaths 2Health News:Higher Medicare spending yields mixed bag for patients 2Health News:Higher Medicare spending yields mixed bag for patients 3Health News:UIC College of Nursing in Peoria Now Accepting Applications for New Doctorate of Nursing Practice 2Health News:UIC College of Nursing in Peoria Now Accepting Applications for New Doctorate of Nursing Practice 3Health News:Most Medicare Drug Plans Continue to Hike Costs into 2008 Two-to-Three Times Rate of Inflation 2Health News:Most Medicare Drug Plans Continue to Hike Costs into 2008 Two-to-Three Times Rate of Inflation 3Health News:LearnSomething Names Deborah Faucette to New Position of Senior Vice President of Sales and Marketing 2Health News:LearnSomething Names Deborah Faucette to New Position of Senior Vice President of Sales and Marketing 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: