Navigation Links
Enanta Reports New Macrolide-Related Drug Class, Bicyclolides, to Combat Hospital and Community Acquired Superbug Infections, Including MRSA
Date:4/10/2008

Data Presented at the 10th Annual Superbugs and Superdrugs Conference on

Antibacterials

WATERTOWN, Mass., April 10 /PRNewswire/ -- Enanta Pharmaceuticals, a leader in the development of small molecule anti-infective drugs, today announced the presentation of their breakthrough research program to evaluate a new macrolide-related drug class, Bicyclolides, in the treatment of methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE), and other gram-positive infection pathogens. Enanta's Bicyclolides have also demonstrated strong activity against MRSA strains resistant to vancomycin, Zyvox(R) (linezolid), and CUBICIN(R) (daptomycin).

The oral presentation, "New Bicyclolides Active Against MRSA and VRE," was presented today during the 10th Annual Superbugs and Superdrugs Conference in London, England.

"Previously, MRSA infection was a problem mainly for patients treated in hospitals," said Robert Moellering, M.D., a professor of medicine at Harvard Medical School and Beth Israel Deaconess Medical Center. "Now we're seeing MRSA in the general community, creating a tremendous need for a new class of antibiotics with improved safety profile and more convenient administration for use within both hospital as well as community settings. The growing problem of bacterial resistance to many existing drugs also necessitates the development of new classes of compounds to fight the battle."

"Pre-clinical research on these new Bicyclolide compounds revealed activity against MRSA and VRE, even against highly drug-resistant MRSA strains. This was an unexpected finding, because traditional macrolides do not work against these bacteria," explained Yat Sun Or, Ph.D., Senior Vice President of Research and Development at Enanta. "These results are also very exciting, because we have observed activity as good as intravenously-administered vancomycin or Zyvox(R) with oral once-a-day dosing lev
'/>"/>

SOURCE Enanta Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. MAP Pharmaceuticals Reports Positive Results From Phase 2a Clinical Trial of Combination Therapy in Adult Asthmatics
2. Catalyst Pharmaceutical Partners Reports Fourth Quarter and Year-End 2007 Financial Results
3. Rexinoid Developed by NuRx Pharmaceuticals Shows Promise in Prevention, Treatment of Lung, Breast Cancer, Paper in Clinical Cancer Research Reports
4. MAP Pharmaceuticals Reports Positive Results From Comparative Pharmacokinetic Trial for its Pediatric Asthma Product Candidate
5. New Study Reports That Physical Therapy Treatment Resolves Symptoms of Urinary Incontinence in Women
6. Ardea Biosciences Reports Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating up to 2.0 Log Reduction in Plasma Viral Load
7. Alexza Reports 2007 Year-End Financial Results and Updates Clinical Pipeline Status
8. NPS Reports Successful GATTEX(TM) Extension Study
9. New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
10. Novavax Reports Fourth Quarter and 2007 Year-End Financial Results
11. GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/15/2014)... 2014 Research and Markets  has announced ... Market Research Report 2014" report to their offering. ... Report 2014 presents comprehensive data on paracetamol (acetaminophen) markets ... Asia , North America ... (acetaminophen) description, covers its application areas and related patterns. ...
(Date:9/15/2014)... , Sept. 15, 2014 Sysmex America, ... information systems technology, announced today an amended distributorship ... is for Sysmex reagents, controls and instruments including ... ™ , Sysmex XP-300™, XT-Series and XN-Series ... is effective immediately and continues until August 31, ...
(Date:9/15/2014)... , Sept. 15, 2014  Mariel Therapeutics, Inc., ... Protein-7 and its application in Osteoarthritis (OA) and Chronic ... experts to its newly formed scientific advisory board. The ... and scientific resource to the company as it continues ... "We are honored to have such leading experts in ...
Breaking Medicine Technology:Paracetamol (Acetaminophen) (CAS 103-90-2) Market Research Report 2014 2Paracetamol (Acetaminophen) (CAS 103-90-2) Market Research Report 2014 3Sysmex America, Inc. Renews LABSCO Distributorship 2Sysmex America, Inc. Renews LABSCO Distributorship 3Mariel Therapeutics Appoints World Leading Experts to Inaugural Scientific Advisory Board 2Mariel Therapeutics Appoints World Leading Experts to Inaugural Scientific Advisory Board 3Mariel Therapeutics Appoints World Leading Experts to Inaugural Scientific Advisory Board 4
... Mass., Aug. 25, 2011 Caliper Life Sciences, ... that its presentation at the Stifel Nicolaus Healthcare ... at 11:30 a.m. EDT.  Kevin Hrusovsky, President and ... on the company,s business. The live webcast can ...
... Aug. 25, 2011 PDI, Inc. (Nasdaq: ... promotional and commercialization services to health care companies, today ... Top 10 pharmaceutical company has been renewed for an ... PDI,s Shared Sales team beginning in September 2011 through ...
Cached Medicine Technology:PDI Announces Renewal of Engagement for 7th Consecutive Season 2
(Date:9/16/2014)... Dr. Eric Millstein of Beverly Hills is ... a specialty website devoted to the diagnosis and treatment ... lover and athlete, Dr. Millstein focuses on offering patients ... to maintain active, healthy lifestyles. , “We’re very excited ... specifically to ACL injuries and treatment,” says ...
(Date:9/16/2014)... 16, 2014 Lambda Solutions, a leader in ... is excited to welcome Stewart Rogers on board ... Executive at Lambda Solutions comments, “Product leadership will take Lambda ... to do so. Learning and talent management is at a ... help clinical learning and talent development in the past ten ...
(Date:9/16/2014)... Texas (PRWEB) September 16, 2014 Online ... be offering $0 shipping on all kettlebell purchases in ... easy for customers to get started with this effective ... the Crossfit movement. The online store carries a variety ... and free weekly workouts guides. , “We’ve ...
(Date:9/16/2014)... justthoughtyoushouldknow.org , popular current events, ... new site today. The new site is better ... information easier to find, ingest, and share. , ... easy-to-read pages the information that we believe any ... retired college professor and founder of the site. ...
(Date:9/16/2014)... 2014 Dakota Software , ... (EHS) and Sustainability management software, today announced that ... versatile software platform, MobileWorkflows, at their Annual Users ... MobileWorkflows allow for on-the-go access to Dakota’s enterprise-level ... Responsive Web Design, MobileWorkflows feature a streamlined user ...
Breaking Medicine News(10 mins):Health News:Los Angeles Orthopedic Surgeon Spotlights ACL Conditions With New Website 2Health News:Los Angeles Orthopedic Surgeon Spotlights ACL Conditions With New Website 3Health News:Stewart Rogers Joins Lambda Solutions as Director of Product Management 2Health News:Stewart Rogers Joins Lambda Solutions as Director of Product Management 3Health News:Join the Kettlebell Movement - Kettlebell Kings Announces $0 Shipping on all Orders 2Health News:JustThoughtYouShouldKnow.org Debuts New Website 2Health News:Mobile EHS Compliance Tools the Focus of Dakota Software’s 2014 Users Conference 2
... In the report titled Millennium Ecosystem Assessment, scientists have said ... having a detrimental effect to human health and may cause ... malaria and cholera are threatening to cause a major outbreak ... beneficial factors of the eco system are being used in ...
... published in American Journal of Public Health, researchers had been ... causes of asthma in children by interventions due to health ... children in the age group of 4 to 12 yrs ... period of one year during which community health workers used ...
... US and Canadian scientists, consuming food with high glycemic index ... ,The study, which had spanned 16.6 years and observed ... that the risk is much significant for women who are ... often found in foods that have simple carbohydrates and sugars ...
... a data comprising of 5461 girls between 11 to 15 ... these girls more prone to stress fractures. ,The study ... physical activity, which often lasts for 16 or more hours ... of having a stress fracture than the girls doing physical ...
... market watchdog Food and Drug Administration had announced a series ... class of non-steroidal anti-inflammatory drugs that are sold with or ... of the drug Bextra (valdecoxib) from Pfizer, Inc. ... FDA had reports that the overall risk associated with the ...
... have completed the second phase of testing of the ... of cervical cancers and 90% of genital warts. ... for 36 months and regularly had gynecological examination, cervicovaginal ... serum antibodies to HPV. , ,The results showed ...
Cached Medicine News:
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: