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Emerald Logic announces collaboration with King's College London on quantitative biomarker discovery
Date:2/6/2013

ALISO VIEJO, Calif., Feb. 6, 2013 /PRNewswire-iReach/ -- King's College London and Emerald Logic, a pioneer in quantitative personalized medicine, have established an ongoing collaboration to identify blood markers for Alzheimer's and other neurological conditions, and to produce screening classifiers by integrating biomarkers with other diagnostic modalities.

The two organizations have already completed ground-breaking work together, identifying 14 discriminative blood markers from a set of over 11,000 markers on 245 study subjects, validated on an additional 82 subjects in two separate hold-out samples.  Using these markers, plus APOE genetic information and demographics, the collaborators produced a mathematical classifier of 94% accuracy in distinguishing Alzheimer's study subjects from controls or with those with mild cognitive impairment.  The biomarker identification and classifier production were completed in six weeks.

Alzheimer's disease affects 1 in 8 people over the age of 65.  Today, there are over 36 million people diagnosed with Alzheimer's worldwide, and equally as many family members spend much of their time caring for these patients.

The key collaborators from King's College London are Simon Lovestone and Richard Dobson .  Dr.  Lovestone is Professor of Old Age Psychiatry at the Institute of Psychiatry (IoP), King's College London, Director of Research at King's Health Partners, and Director of the National Institute for Health Research Biomedical Research Centre (NIHR BRC) for Mental Health at the South London and Maudsley NHS Foundation Trust (SLAM) and King's College London.  Dr. Dobson is Bioinformatics Lecturer at the NIHR BRC for Mental Health at SLAM and King's and at the IoP at King's.

Professor Lovestone says:  "Emerald Logic's software evolved Alzheimer's disease
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SOURCE Emerald Logic
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