Embryo Viability Studies Support Utility of Novel, Metabolomic Profiling ...(c technologymay favorably impact IVF out...),Health

Date:7/7/2008

c technology may favorably impact IVF outcomes by improving procedures to more accurately predict embryo viability and reproductive potential. Having the ability to reliably select viable embryos will allow infertility specialists to reduce the number of embryos transferred in IVF and thus decrease the incidence of multiple gestations."

Embryo and Blastocyst Profiling

Two other presentations -- "Metabolic modifications of culture medium by human embryos; correlations with embryonic characteristics and outcome in single embryo transfers," and "Non-invasive metabolic profiling of day 5 spent culture media aids in the prediction of blastocyst viability" -- further highlighted the potential applications of Molecular Biometrics' proprietary metabolomic technology. The first study demonstrated that embryos that implant following transfer alter their culture media differently from embryos that failed to implant. These differences were readily detectable using the company's metabolomics platform. Viability scores, generated based on these metabolomic differences, were significantly more accurate than currently-used morphological measures in identifying viable embryos capable of implantation. The second study determined that metabolomic profiling of blastocysts can also be used to assess viability of these advanced stage embryos as well.

Metabolomics at Molecular Biometrics

Metabolomics is a complex scientific process that identifies and measures individual signals from many small molecular compounds produced by cellular metabolism which, when evaluated as a whole, represent unique biomarkers of biologic function in health and disease.

Molecular Biometrics uses near infrared (NIR) biospectroscopy in its metabolomic applications. NIR is a robust platform that rapidly measures the vibrational energy produced by small molecule functional groups, creating a profile of molecules that are descriptive of cellular function and viability.

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SOURCE Molecular Biometrics, LLC Copyright©2008 PR Newswire. All rights reserved

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