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Ellex 2RT Study Demonstrates Clinical Efficacy in Treatment of Diabetic Macular Edema
Date:11/10/2007

ctive RPE treatment in diabetic maculopathy and macular edema. The duration of the study is 12 months with patient follow up at three, six and twelve months post-op. All patients received treatments with Ellex 2RT prototype lasers that were developed specifically for the Ellex 2RT research program by Ellex's advanced research team in Adelaide, Australia. Ellex has international patents pending for the technology and the method.

At three months the majority of patients experienced improvement in visual acuity and central macular thickness (CMT) as measured by optical coherence tomography. Central macular thickness decreased in 55% of eyes and remained stable in 24%. An increase in central macular thickness was observed in only 20% of eyes. In addition, micro-perimetry confirmed that there was no evidence of laser damage to the photoreceptor cells.

ABOUT ELLEX 2RT RESEARCH

Ellex 2RT research is funded in part by an A$1.9 million, two-year Commercial Ready Grant awarded to Ellex by the Australian Government to support the development of a new and innovative laser therapy for the treatment of AMD and other retinal diseases. The grant was applied for in order to expand laboratory and clinical research in Australia based on proof- of-principle laboratory work conducted at St. Thomas' Hospital in London under the direction of Professor Marshall. Ellex 2RT clinical trials will next commence in Australia, followed by multiple centers internationally over the next 12 months. These trials will provide data necessary to develop a commercial product based on the current prototype 2RT laser systems. The company estimates it will take six months to one year to design and release a product for sale once a decision is made to commercialize Ellex 2RT.

ABOUT AMD

AMD causes central visual loss and is the leading cause of blindness for people over the age of 60. The U.S. National Eye Institute estimates that there are 1.8 million people with AMD in the Unit
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SOURCE Ellex Medical Lasers Limited
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