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Elanco Launches Broad-Spectrum Canine Parasiticide
Date:1/17/2011

r than three monthly doses after the last exposure to mosquitoes may not provide complete heartworm prevention. Prior to administration of Trifexis, dogs should be tested for existing heartworm infection. Use with caution in breeding females. The safe use of Trifexis in breeding males has not been evaluated. Use with caution in dogs with pre-existing epilepsy. Puppies less than 14 weeks of age may experience a higher rate of vomiting. If vomiting occurs within an hour of administration, redose with another full dose. The most common adverse reactions recorded during clinical trials were vomiting, pruritus, lethargy and diarrhea. For product label, including complete safety information, see attached.

Important safety information about ComfortisThe most common adverse reaction reported is vomiting. Other adverse reactions reported in decreasing order of frequency are: depression/lethargy, decreased appetite, incoordination, diarrhea, itching, trembling, excessive salivation and seizures. Following concomitant extra-label use of ivermectin with Comfortis, some dogs have experienced the following clinical signs: trembling/twitching, salivation/drooling, seizures, incoordination, excessive dilation of pupils, blindness and disorientation. Post-approval experience continues to support the safety of Comfortis when used concurrently with heartworm preventatives according to label directions. For product label, including complete safety information, see attached label.

About AssurityAlways read, understand and follow label and use directions.

(1) For full study details, see Comfortis FOI: NADA 141-277 at www.fda.gov.

(2) The Presidential Green Chemistry Challenge Award; www.epa.gov

(3) Ipsos-Forward/Elanco Market Research, August 2010'/>"/>

SOURCE Elanco Companion Animal Health
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