Navigation Links
Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery
Date:12/12/2011

oxaban 30 mg once daily and enoxaparin 20 mg (2,000 IU) in the prevention of VTE in 610 Japanese patients undergoing THA[ii].

Both studies supported the March 2010 edoxaban New Drug Application (NDA) in Japan seeking approval for the prevention of VTE after major orthopedic surgery. In the studies, edoxaban was initiated six to 24 hours after surgery; enoxaparin was initiated 24 to 36 hours after surgery, the standard of care in Japan. The primary efficacy outcome in both studies was the composite of symptomatic and asymptomatic DVT and PE. The principal safety outcome was incidence of major and clinically relevant non-major bleeding.

About Venous Thromboembolism (VTE)
VTE is the term for the generation of a blood clot within a vein, or the subsequent breaking off of that clot into a pulmonary (lung) artery. Deep vein thrombosis (DVT) and pulmonary embolism (PE) are the two sub-types of VTE. DVT is a blood clot anywhere in the deep veins of the legs, pelvis or arms. PE is a clot that detaches from the vein and travels to the lungs, lodging in the pulmonary arteries causing a potentially fatal condition. PE is often accompanied by DVT and a DVT can develop into a PE suddenly.

Patients with diagnosed VTE are treated for three to six months (and sometimes even longer) based on their individual risk profile to prevent a second (recurrent) DVT or PE. VTE is the cause of significant mortality; 30 percent of people with VTE die within one month of diagnosis and about 25 percent of those with PE experience sudden death. Additionally, about 30 percent of those affected will experience a recurrence of DVT/PE within 10 years of the initial DVT/PE diagnosis.[v]

About Daiichi Sankyo
The Daiichi Sankyo Group is dedicated to the creation and supply of innovative pharmaceutical products to address the diversified, unmet medical needs of patients in both mature and emerging markets. While maintaining its port
'/>"/>

SOURCE Daiichi Sankyo Company, Limited
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing
2. Daiichi Sankyo Receives First Market Approval in Japan for LIXIANA® (edoxaban), a Direct Oral Factor Xa Inhibitor, for the Prevention of Venous Thromboembolism after Major Orthopedic Surgery
3. Daiichi Sankyo Launches LIXIANA® (edoxaban), a Direct Oral Factor Xa Inhibitor, in Japan for the Prevention of Venous Thromboembolism after Major Orthopedic Surgery
4. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
5. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
6. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
7. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
10. Promising Phase 3 Trial Results Show Novel Biologic Therapy Ustekinumab (CNTO 1275) Significantly Improved Psoriasis
11. INVEGA(TM) Significantly Reduced Symptoms of Schizophrenia Compared to SEROQUEL(R) in Acutely Ill, Hospitalized Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... Thirty-six million Americans suffer from hearing loss, ... National Hearing Month – more than 28 million Americans ... the sounds of spring, like birds singing and the ... that you won,t be among those missing out on ... offers practical advice: Take action if you ...
(Date:5/4/2015)... -- Impax Laboratories, Inc. (NASDAQ: IPXL ) announced that ...  Donna M. Hughes, as Senior Vice President, Human Resources ... President, Chief Compliance Officer. Both Ms. Hughes and Ms. ... Officer, Fred Wilkinson . "We are ... team," said Fred Wilkinson , President and Chief ...
(Date:5/4/2015)... Bayer HealthCare (Bayer) has entered into an ... ISIS ) on ISIS-FXI Rx, an antisense investigational ... Under the agreement Bayer will further develop and commercialize ... need. As part of the clinical development program, Bayer ... in an appropriate patient community. "Bayer ...
Breaking Medicine Technology:It's Better Hearing Month 2Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 2Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 3Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 2Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 3
... Sept. 2 NewCardio (OTC Bulletin Board: NWCI ... Renz, Jr., NewCardio,s President and CEO, purchased 128,000 shares during ... weeks following the Company,s filing of its SEC Form 10-Q ... 2010. "As discussed on our August 12, ...
... SKILLMAN, N.J., Sept. 2 ConvaTec, a world-leading developer ... hospital care, announced today the introduction of a new, ... with Strengthening Fibers, now available in the U.S. and ... highly exuding chronic and acute wounds. The new dressing, ...
Cached Medicine Technology:NewCardio CEO Increases Equity Position 2NewCardio CEO Increases Equity Position 3NewCardio CEO Increases Equity Position 4ConvaTec Expands AQUACEL® Dressing Product Line With Introduction of New Ribbon Dressing 2ConvaTec Expands AQUACEL® Dressing Product Line With Introduction of New Ribbon Dressing 3ConvaTec Expands AQUACEL® Dressing Product Line With Introduction of New Ribbon Dressing 4
(Date:5/4/2015)... New York, NY (PRWEB) May 04, 2015 ... the 2015 International Champions Cup (ICC) . While ... the world and is held every four years, the International ... Last year, the tournament saw the all-time attendance record for ... Real Madrid from the Big House at the University of ...
(Date:5/4/2015)... City, OK and Seattle, WA (PRWEB) May 04, 2015 ... announced the formation of a collaboration to facilitate development ... number of ophthalmic disorders that lead to blindness, including ... to the MiDROPS™ formulation platform developed by EyeCRO, which ... the eye via a topical eyedrop. , Under ...
(Date:5/4/2015)... VA (PRWEB) May 04, 2015 Ticket Down ... at the John Paul Jones Arena in Charlottesville, VA. ... the history of the music business and this beloved performer ... Paul McCartney, the former member of two legendary groups: Wings ... in the music business since 2013 on the “Out There” ...
(Date:5/4/2015)... May 04, 2015 New findings released ... Tumor Association (ABTA) show that people diagnosed with a ... treatment options, including clinical trials, at the time of ... make difficult decisions about their course of treatment. The ... the first nationwide brain tumor volunteer network, the ABTA ...
(Date:5/4/2015)... 2015 Pricing Healthcare announces it ... one patient receiving care at St. George Surgical Center ... must be performed by July 15th, 2015, and the patient ... up front and forego the filing of insurance claims). , ... every year, and it devastates more and more individuals and ...
Breaking Medicine News(10 mins):Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 2Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 3Health News:Cheap 2015 International Champions Cup (ICC) Tickets: Ticket Down Slashes Ticket Prices on International Champions Cup (ICC) Presale Tickets 4Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 2Health News:EyeCRO and NeuMedics Announce Collaboration to Utilize MiDROPS™ Technology for the Development of NM108 3Health News:Paul McCartney Tickets at John Paul Jones Arena in Charlottesville, VA: Ticket Down Slashes Paul McCartney Ticket Prices in Charlottesville at the John Paul Jones Arena 2Health News:American Brain Tumor Association Poll Underscores Need for Greater Awareness and Education at Time of Diagnosis 2Health News:American Brain Tumor Association Poll Underscores Need for Greater Awareness and Education at Time of Diagnosis 3Health News:Pricing Healthcare to Pay a Patient's Bill for a Procedure at Utah Facility 2Health News:Pricing Healthcare to Pay a Patient's Bill for a Procedure at Utah Facility 3
... in patients with metastatic breast cancer, especially in those ... epidermal growth factor receptor-2) positive, a surgical oncologist will ... Breast Cancer Conference (EBCC7). Dr Marie Sundquist, ... will say that the median survival times for five-year ...
... ... leading Pediatrician Dr. William Lawrence Jr. of Sixty Second Parent encouraged parents to continue ... ... National Nutrition Month draws to a close, leading Pediatrician Dr. William Lawrence Jr. of ...
... ... of Shimmering Resumes, offers to help former Bush speechwriter David Frum with his resume. ... strategy on healthcare reform. , ... (PRWEB) March 26, 2010 -- Paul Freiberger, the President of Shimmering Resumes, ...
... ... accidents , ... March 26, 2010 -- With the arrival of spring, more cyclists are planning to enjoy the ... people sharing the road with drivers and pedestrians., , , , ,This week bikers complained to ...
... ... disorders and improve dental procedures. , ... Miami, FLA. (PRWEB) -- In addition to cosmetic dentistry services, including veneers and ... Institute now offer dental massage to patients. Dr. Nassery teams up with Love Life Massage, ...
... Women who discover they have breast cancer while they ... the health of their unborn baby, according to research ... Conference (EBCC7) in Barcelona today (Friday). Dr Sibylle ... University of Frankfurt, Germany, and a member of the ...
Cached Medicine News:Health News:Survival in metastatic breast cancer patients is improving: targeted therapies have contributed 2Health News:Eating Habits Start Early - Parents must be Good Role Models for Healthy Kids 2Health News:President of Shimmering Resumes Offers Professional Resume To Bush Speechwriter, David Frum 2Health News:New York Personal Injury Attorney Interprets Increase in Tickets for Cyclists as Effort to Make Streets Safer 2Health News:Top Miami Dentist, Dr. Hamid Nassery, Offers Dental Massage Services For Patients 2Health News:Pregnant women can receive breast cancer chemotherapy without endangering health of their babies 2Health News:Pregnant women can receive breast cancer chemotherapy without endangering health of their babies 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: