Navigation Links
Edoxaban Significantly Reduces Risk of Venous Thromboembolism by Half Compared to Enoxaparin in Japanese and Taiwanese Patients Following Knee or Hip Arthroplasty Surgery
Date:12/12/2011

oxaban 30 mg once daily and enoxaparin 20 mg (2,000 IU) in the prevention of VTE in 610 Japanese patients undergoing THA[ii].

Both studies supported the March 2010 edoxaban New Drug Application (NDA) in Japan seeking approval for the prevention of VTE after major orthopedic surgery. In the studies, edoxaban was initiated six to 24 hours after surgery; enoxaparin was initiated 24 to 36 hours after surgery, the standard of care in Japan. The primary efficacy outcome in both studies was the composite of symptomatic and asymptomatic DVT and PE. The principal safety outcome was incidence of major and clinically relevant non-major bleeding.

About Venous Thromboembolism (VTE)
VTE is the term for the generation of a blood clot within a vein, or the subsequent breaking off of that clot into a pulmonary (lung) artery. Deep vein thrombosis (DVT) and pulmonary embolism (PE) are the two sub-types of VTE. DVT is a blood clot anywhere in the deep veins of the legs, pelvis or arms. PE is a clot that detaches from the vein and travels to the lungs, lodging in the pulmonary arteries causing a potentially fatal condition. PE is often accompanied by DVT and a DVT can develop into a PE suddenly.

Patients with diagnosed VTE are treated for three to six months (and sometimes even longer) based on their individual risk profile to prevent a second (recurrent) DVT or PE. VTE is the cause of significant mortality; 30 percent of people with VTE die within one month of diagnosis and about 25 percent of those with PE experience sudden death. Additionally, about 30 percent of those affected will experience a recurrence of DVT/PE within 10 years of the initial DVT/PE diagnosis.[v]

About Daiichi Sankyo
The Daiichi Sankyo Group is dedicated to the creation and supply of innovative pharmaceutical products to address the diversified, unmet medical needs of patients in both mature and emerging markets. While maintaining its port
'/>"/>

SOURCE Daiichi Sankyo Company, Limited
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Analysis of Edoxaban Phase II Data Provides Insight Into Reduced Bleeding Events Seen in Once-Daily Dosing
2. Daiichi Sankyo Receives First Market Approval in Japan for LIXIANA® (edoxaban), a Direct Oral Factor Xa Inhibitor, for the Prevention of Venous Thromboembolism after Major Orthopedic Surgery
3. Daiichi Sankyo Launches LIXIANA® (edoxaban), a Direct Oral Factor Xa Inhibitor, in Japan for the Prevention of Venous Thromboembolism after Major Orthopedic Surgery
4. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
5. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
6. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
7. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
10. Promising Phase 3 Trial Results Show Novel Biologic Therapy Ustekinumab (CNTO 1275) Significantly Improved Psoriasis
11. INVEGA(TM) Significantly Reduced Symptoms of Schizophrenia Compared to SEROQUEL(R) in Acutely Ill, Hospitalized Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... Pharma Major Lupin Limited ... en ZAO "Biocom" en Rusia bajo ciertas condiciones ... Lupin en el mercado farmacéutico de Rusia que ... como uno de los 10 principales mercados farmacéuticos ... de una década, el mercado farmacéutico ruso registró ...
(Date:7/2/2015)... DIEGO , July 2, 2015 ResMed Inc. ... its fourth quarter and fiscal year ended June 30, 2015 ... Stock Exchange market close. A press release with ResMed,s results ... the company will host a webcast to discuss operating results ... to begin at 1:30 p.m. US Pacific Time and the ...
(Date:7/2/2015)... 2, 2015 Releases of the ... Aedes aegypti , , reduced the dengue mosquito ... by 95%, well below the modelled threshold ... , The journal PLOS Neglected Tropical Diseases ... genetically engineered mosquitoes. The results showed that in Juazeiro ...
Breaking Medicine Technology:Lupin adquiere Biocom en Rusia 2Lupin adquiere Biocom en Rusia 3ResMed to Announce Fourth Quarter and Fiscal Year-End 2015 Results 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 2Oxitec Mosquito Works to Control Aedes aegypti in Dengue Hotspot 3
(Date:7/2/2015)... ... ... is pleased to announce the opening of its newest location in Dallas, Texas. The opening ... yogurt chain was listed as #22 on the Inc. 500 list of fastest growing companies ... is located at:, 3701 W. Northwest Highway, STE 430, Dallas, TX 75220 , “We are ...
(Date:7/2/2015)... ... , ... Many Fourth of July celebrations will include fireworks this summer, so ... sharing some tips to promote the proper use of fireworks. , According to the ... daily with fireworks-related injuries in the month surrounding the Fourth of July. Amica is ...
(Date:7/2/2015)... ... July 02, 2015 , ... ... of the SIGVARIS PERFORMANCE SOCKS. Since the socks were first introduced, they have ... Their significant popularity has inspired four new, fun shades including: blue, lime, pink ...
(Date:7/2/2015)... ... July 02, 2015 , ... When ... Coalition met for the late June Web-based session, the speakers discussed the importance ... and managing high-risk patients through coordinated care. , During the session, participants learned ...
(Date:7/2/2015)... ... July 02, 2015 , ... Real Time Pain Relief (RTPR), makers of the popular ... Big Sky PBR to sponsor The Fifth Annual Big Sky Professional Bull Riders Event ... product samples of their popular pain relief lotion and products at the family friendly event ...
Breaking Medicine News(10 mins):Health News:sweetFrog Opens 18th Location in the Lone Star State 2Health News:6 Fireworks Safety Tips from Amica Insurance 2Health News:SIGVARIS is Sporting Four Brand New Colors in the Popular PERFORMANCE SOCK Product Line 2Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 2Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 3Health News:ACO Coalition Discusses the Future of Medicare Payments and the Benefits of Providing More Care 4Health News:Real Time Pain Relief Sponsors The Fifth Annual Big Sky Professional Bull Riders Event at Big Sky Town Center in July 2Health News:Real Time Pain Relief Sponsors The Fifth Annual Big Sky Professional Bull Riders Event at Big Sky Town Center in July 3
... has detected on Sunday five new suspected cases of avian flu ... where the deadly virus was first isolated in October.// ... in a village of Padina showed presence of bird flu. ... strain. ,Avian flu has been found in birds in ...
... been claimed in treating AIDS patients using a herbal concoction ... blood cell count. // ,Dr P L Meenakshisundaram, ... ,Herbal medicine helped HIV patients to gain weight and their ... research and clinical trials done over a period ranging from ...
... of Washington University writes in his latest book Doctor’s ... has been a great scientist, inventor, publisher and statesman.// ... education has contributed a lot to preventive and modern ... America during the 18th Century in a period where ...
... actress Catherine Zeta Jones has made a New Year's resolution ... afraid of the impact her deadly habit will have on ... because her two children, Dylan-five and two-year-old Cary are approaching ... every little thing around. ,I have to stop as ...
... Doctor Robin Warren, the Australian Nobel Prize winners for medicine ... glitzy ceremony at Stockholm yesterday. // ,The ... belief in their concept. Professor Marshall and Dr Warren were ... and not by stress or lifestyle changes as previously believed. ...
... conducted by Steven H. Woolf, M.D., professor and director of ... reported that it will be fruitful // and more lives ... medical facilities and provided the existing facilities to the public. ... of Health (NIH) to improve treatment modalities of which only ...
Cached Medicine News:Health News:Stop spending on new treatments; allocate funds to improve the existing treatments. 2
... The Carriazo-Pendular microkeratome is based ... of the cornea during the cut., ... applanated evenly from the beginning of ... ensures that the intraocular pressure does ...
... Nicknamed the SRS, this new and innovative stent ... the office right at the chair with just ... medical grade silicone and is available in three ... separately). At each end of the stent is ...
... introduces the Halo Cordless Surgical Headlight, the ... headlight. Illuminated by innovative LED technology, and ... bright, white, cool light, guaranteeing phenomenal light ... hours of surgery. The Halo delivers a ...
... Using flying spot technology the Technolas 217z ... for personalized vision correction, allows surgeons in ... to -7.00 Diopters and astigmatism up to ... combines both a 2mm and 1mm truncated ...
Medicine Products: