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Early Esophageal Cancer and Pre-Cancer Eliminated With Non-Surgical Treatment Combination
Date:5/20/2008

Endoscopic ablative therapy with HALO device leads to 100% patient response

rate

SUNNYVALE, Calif., May 20 /PRNewswire/ -- BARRX Medical, Inc., a global technology leader in treating Barrett's esophagus, today announced the publication of two related European trials which report a 100% eradication rate for early esophageal cancer and pre-cancerous dysplasia using endoscopic resection followed by ablation therapy with the HALO ablation system. Barrett's esophagus is a complication of gastroesophageal reflux disease (GERD) and is a known risk factor for esophageal cancer, the fastest growing cancer in the Western world.

Results of the two studies were published in the May issue of Endoscopy, a medical journal for gastroenterologists performing advanced endoscopic procedures. They were titled "Effective treatment of early Barrett's neoplasia with stepwise circumferential and focal ablation using the HALO system," and "Stepwise circumferential and focal ablation of Barrett's esophagus with high- grade dysplasia: results of the first prospective series of 11 patients." The investigators enrolled patients with Barrett's esophagus having early cancer and/or advanced dysplasia, used endoscopic resection to remove focal abnormal areas, then used endoscopic ablative therapy with the HALO system to eradicate all remaining diseased tissue. At one and two year follow-up, respectively, in each trial, all patients were cured of their esophageal disease.

"This data confirms that early cancer and advanced dysplasia can be safely and effectively treated with this non-surgical approach using endoscopic resection and ablation," said Amsterdam Medical Centre (AMC) gastroenterologist and Professor of Medicine Jacques Bergman, M.D., who led the study in Amsterdam, the Netherlands. "We're confident this treatment can reduce the need for high risk surgical procedures and become the preferred strategy for treating patients with Ba
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SOURCE BARRX Medical, Inc.
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