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EUSA Pharma Acquires Development and Commercialization Rights to ASPAREC® for Treatment of Acute Lymphoblastic Leukemia from Alizé Pharma
Date:2/2/2012

izes our drug development capabilities, and fits well with our business strategy, which is to establish partnerships with the pharmaceutical industry early in the development of our programs in order to secure both near-term and long-term revenue streams."

About acute lymphoblastic leukemia

Acute lymphoblastic leukemia is the most common form of childhood cancer, with approximately 2,900 patients under the age of 20 diagnosed in the USA each year [1].  It is also one of the most curable forms of cancer, with remission rates in treated children of over 95% and 75 - 85% surviving at least five years without recurrence of leukemia [1].  Treatment involves a number of stages and drugs, and typically includes asparaginase as an essential component of current protocols.  

About asparaginase and ASPAREC

Asparaginase enzymes deplete the level of asparagine in the bloodstream.  Asparagine is essential for cell growth, and its removal from the blood inhibits the growth of cells associated with acute lymphoblastic leukemia.  Asparaginase treatments are derived from bacteria, and approximately 15 - 20% of patients develop hypersensitivity to modern products derived from Escherichia coli, preventing their continued treatment [2].  ASPAREC is a proprietary recombinant, pegylated Erwinia chrysanthemi-derived asparaginase in development for the treatment of acute lymphoblastic leukemia in patients with hypersensitivity to E. coli-derived therapies.  Preclinical data indicate ASPAREC is potentially longer acting and less immunogenic than currently available asparaginase Erwinia chrysanthemi.  

About EUSA Pharma

EUSA Pharma is a rapidly growing transatlantic specialty pharmaceutical company focused on oncology, oncology supportive care and critical care products.  The company has an established commercial infrastructure in the US, a pan-European presence and a wider dist
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