Navigation Links
ERBITUX(R) Meets Primary Endpoint of Increasing Survival in Phase III Lung Cancer Study
Date:9/10/2007

ere observed in a single-arm trial with ERBITUX, delayed, accelerated (concomitant boost) fractionation radiation therapy, and cisplatin (100 mg/m2) conducted in patients with locally advanced squamous cell carcinoma of the head and neck. Two of 21 patients died, one as a result of pneumonia and one of an unknown cause. Four patients discontinued treatment due to adverse events. Two of these discontinuations were due to cardiac events (myocardial infarction in one patient and arrhythmia, diminished cardiac output, and hypotension in the other patient).

In women of childbearing potential, appropriate contraceptive measures must be used during treatment with ERBITUX and for 6 months following the last dose of ERBITUX. If ERBITUX is used during pregnancy or if patients become pregnant while receiving ERBITUX , patients should be apprised of the potential risk for loss of pregnancy or potential hazard to the fetus.

The incidence of hypomagnesemia (both overall and severe [NCI CTC Grades 3 & 4]) was increased in patients receiving ERBITUX alone or in combination with chemotherapy as compared to those receiving best supportive care or chemotherapy alone based on ongoing, controlled clinical trials in 244 patients. Approximately one-half of these patients receiving ERBITUX experienced hypomagnesemia and 10-15% experienced severe hypomagnesemia. Electrolyte repletion was necessary in some patients and in severe cases, intravenous replacement was required. Patients receiving ERBITUX therapy should be periodically monitored for hypomagnesemia, and accompanying hypocalcemia and hypokalemia during, and up to 8 weeks following the completion of, ERBITUX therapy.

The most serious adverse reactions associated with ERBITUX in combination with radiation therapy in 208 patients with head and neck cancer were infusion reaction (3%), cardiopulmonary arrest (2%), dermatologic toxicity (2.5%), mucositis (6%), radiation dermatitis (3%), confusion (2%), and diarrhea (2%).
'/>"/>

SOURCE ImClone Systems Incorporated; Bristol-Myers Squibb Company
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. ENDEAVOR IV Clinical Trial Meets Primary Endpoint
2. Second Phase III Study Evaluating Gileads Viread for the Treatment of Chronic Hepatitis B Virus Meets Primary Endpoint
3. Second Phase III Study Evaluating Gileads Viread for the Treatment of Chronic Hepatitis B Virus Meets Primary Endpoint
4. Neoprobe Phase 2 Lymphoseek Trial Meets Primary Endpoint
5. Phase III Study Evaluating Gileads Viread for the Treatment of Chronic Hepatitis B Virus Meets Primary Endpoint
6. SciClone and Sigma-Tau Report Thymalfasin Meets Primary Endpoint in Phase 2 Malignant Melanoma Trial
7. GlaxoSmithKline’s Hib-MenCY-TT Combination Vaccine Meets Phase II Study Endpoints of Immunogenicity and Safety Compared to Licensed Vaccines
8. YM BioSciences Reports AeroLEF Randomized Phase IIb Trial Meets Primary Endpoint in Patients with Post-Surgical Pain
9. DX-88 for Hereditary Angioedema Meets Primary and Secondary Endpoints in Phase 3 Trial (EDEMA3)
10. Alexzas AZ-004 Phase IIa Trial Meets Primary Endpoint in Treating Schizophrenic Patients With Acute Agitation
11. Replidyne Phase II Pediatric Trial Meets Primary Objective
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... de agosto de 2015   Royal Philips ... en el  Congreso de la ESC de 2015 ... y novedosas, entre ellas HeartModel A.I.  , EchoNavigator ... y la tecnología con los protocolos de atención ... tratamientos y permitir atención en el hogar. ...
(Date:8/27/2015)... 27, 2015 DURECT Corporation (Nasdaq: DRRX ... at three upcoming healthcare conferences.  , ... present at the Rodman & Renshaw Investment Conference on ... conference is being held at the St. Regis Hotel ... live audio webcast of the presentation will be available ...
(Date:8/27/2015)... MEETING, Pa. , Aug. 27, 2015  Now ... decommissioning the Da Vinci S™ surgical robot, hospitals with ... replacement plans. They also need to see where they ... procedures on the right patients? Have they adopted best ... robotic surgery program in the future? ECRI ...
Breaking Medicine Technology:Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 2Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 3Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 4Philips presenta nuevas soluciones cardiológicas integradas para desarrollar procedimientos menos invasivos 5DURECT to Participate in Upcoming Healthcare Conferences 2ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 2ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 3
... Rcadia Medical Imaging has achieved proof-of-concept with the first ... a coronary CT angiography (cCTA) study. This technology, the ... scoring, has the potential to eliminate the need for ... costs  and decrease patient radiation exposure. This work in ...
... The Renal Therapies Division of B. ... of the Plasmat™ Futura System for H.E.L.P. ®   ... H.E.L.P. ® therapy provides a more easy-to-use system ... patients with severe hypercholesterolemia. (Logo: http://photos.prnewswire.com/prnh/20081022/NYW008LOGO) ...
Cached Medicine Technology:Rcadia's Fully Automatic Calcium Score Assessment from Coronary CTA Shows Potential to Eliminate Need for Separate Scan 2B. Braun Renal Therapies Division Announces Availability of Advanced Apheresis Therapy System 2
(Date:8/28/2015)... ... August 28, 2015 , ... Healthpointe clinics throughout ... go deep sea diving. The act of recreational diving exposes the body ... reasons, it is vital that all recreational and professional divers undergo regular comprehensive ...
(Date:8/28/2015)... , ... August 28, 2015 ... ... Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive information on two ... demonstration approved for a December 2015 launch; and Idaho’s partnership to revamp ...
(Date:8/28/2015)... ... August 28, 2015 , ... External Counterpulsation, also known as ECP or EECP, ... External Counterpulsation (EECP or ECP) machines with a full clinic licence to help people ... since 2007 helping people prevent and reverse heart disease through its evidence-based ...
(Date:8/28/2015)... ... August 28, 2015 , ... A complimentary webinar offered by healthcare ... Medicaid Services’ (CMS) proposal to mandate bundled payments through the Comprehensive Care ... for Game Day: Comprehensive Care for Joint Replacement,” takes place at 12 noon EDT ...
(Date:8/28/2015)... ... August 28, 2015 , ... An independent study ... in high percentages of change to treatment recommendations and diagnosis. The 2015 return ... Tennessee Tech University and analyzed WorldCare’s second opinion process. , The study reviewed ...
Breaking Medicine News(10 mins):Health News:Healthpointe Now Offering Scuba Physicals 2Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:Buy New External Counterpulsation (EECP or ECP) With Heart Fit Clinic 2Health News:PYA Offers Complimentary CCJR Webina — Game On 2Health News:PYA Offers Complimentary CCJR Webina — Game On 3Health News:WorldCare International, Inc. Celebrates Findings of Independent ROI Study 2
... Society of,Transplantation (AST) is hitting the road to spread ... -- human resource professionals., AST is scheduled to ... Management (SHRM) nationwide to promote the Society,s Employee,Leave and ... to adopt paid leave policies for employees who act ...
... deliver healthcare to patients is key to ensuring that Medicare ... boomers according to a new paper by Geisinger Health System ... as the paper points out, is that the solutions are ... develop financial incentives that reward providers when better care is ...
... natural sweet defeats the bacteria that drive the ailment, ... Honey may help bring sweet relief to chronic sinusitis ... germ fighters in honey attack the bacteria that cause ... traditional medicine as a natural anti-microbial dressing for infected ...
... 24 For the first time, accumulated ... cancer, especially,ovarian and uterine (endometrial) cancers, experience ... oncologist. The 2008 State of the State,of ... Women of America,published by the Gynecologic Cancer ...
... Workers Struggle to Improve Care for the Sick & Elderly ... Facilities Owned By ... 700 healthcare,workers began a two-day unfair labor practice strike Wednesday ... delivery of patient care to hundreds of sick and elderly ...
... DIEGO, Sept. 24 The World Privacy ... Requirements: Suggestions for,Health Care Providers, discusses the ... health care sector along with suggestions for ... the Federal Trade,Commission that require financial institutions ...
Cached Medicine News:Health News:AST to Address Human Resources Groups Nationwide to Encourage them to Adopt a Paid Leave Plan for Organ Donors 2Health News:Geisinger study: Increasing health care value improves health care quality 2Health News:A Honey of a Sinusitis Treatment 2Health News:A Honey of a Sinusitis Treatment 3Health News:Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist 2Health News:Ovarian and Endometrial Cancer Patients Experience Improved Outcomes When Treated First by a Gynecologic Oncologist 3Health News:Caregivers Hold Unfair Labor Practice Strike to Improve Quality of Resident Care at Statewide Nursing Home Chain 2Health News:Caregivers Hold Unfair Labor Practice Strike to Improve Quality of Resident Care at Statewide Nursing Home Chain 3Health News:(Report) World Privacy Forum Publishes Red Flag Rule Suggestions for Hospitals and Providers; New FTC-Enforced Rules Go Into Effect Nov. 1, Can Apply to Health Care Providers 2
Demineralized Freeze-dried Bone Allograft (DFDBA) processed from cortical bone. Demineralized cortical powder is free of all soft tissue....
Dedicated ENT electromagnetic surgical navigation system. Value priced for comunity hospitals and surgical centers....
... The Summit SI Spinal Fixation ... for rigid posterior fixation of ... spine. The simplicity and versatility ... optimize the construct based on ...
...
Medicine Products: