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Dynamine® [NEW CLINICAL TRIAL]: Researchers discovered that Dynamine® extends caffeine’s half-life and increased its area under the curve approximately two-fold

SELF-AFFIRMED GRAS Dynamine®, is a rapid-onset energy and focus ingredient that increases perceived energy, alertness, productivity and motivation to perform mental tasks. Like Teacrine®, Dynamine® may amplify feelings of energy, mood and focus by activating dopamine receptors and other key neurotransmitters, inhibiting adenosine receptors, all without elevating heart rate or blood pressure.

There have been numerous studies on compounds which may enhance the beneficial effects of caffeine on energy, mood/motivation and focus. Recently, a landmark clinical trial was conducted at a major Division I university to investigate Dynamine®'s potential pharmacokinetic interaction with caffeine and Teacrine®. Remarkably, researchers discovered that Dynamine® extended caffeine’s half-life and increased its area under the curve approximately two-fold. The reverse was not true (i.e. caffeine did not alter Dynamine®'s pharmacokinetics). In addition, researchers also discovered that co-administration of Teacrine® and Dynamine® increased the half-life of caffeine approximately three-fold.

Collectively, these data have widespread implications for product formulations that utilize these compounds and suggest that lower doses of caffeine may be used in products containing Dynamine®. Future studies are needed to confirm these effects and refine dosage recommendations.

Matt Titlow, CEO of Compound Solutions commented: "We're excited and enthusiastic about the remarkable new Dynamine®-Caffeine pharmacokinetic clinical study results, and implications for all stakeholders from brand owners to consumers! Given the surge of interest in amplifying the efficacy of caffeine, while minimizing adverse or undesirable effects in the healthy energy, cognitive performance, brain health product categories, these new data provides support for either driving more efficacy out of a given dose of caffeine, or lowering caffeine doses while maintaining or improving its wide-ranging benefits," Matt concluded.

Compound Solutions is the go-to company representing and distributing unique, patented nutraceutical ingredients that improve the health and performance of individuals. CSI supplies effective, science-based, ingredients to sports nutrition, functional food and nutraceutical manufacturers. We are committed to building and maintaining long-term relationships with our global customers and suppliers.

If you are attending Natural Products Expo West from March 5-7,2020, reach out to us at if you would like to schedule a meeting with our sales or marketing team! Or simply stop by booth # 3983 and chat with us about Dynamine® and the rest of our trademarked and patented ingredients.

The structure/function claims appearing in CSI marketing materials are for informational purposes only. Customers should review relevant data and arrive to their own determinations regarding whether specific structure/function claims are properly substantiated based on their own formulations. Ultimately, the Customer is responsible for the claims that they make on their product(s) and should review all claims with their legal counsel prior to making the claim(s).

**These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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