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Dynamic Reciprocity Examined as Scientific Framework for Wound Healing in March/April Issue of Wound Repair and Regeneration
Date:4/5/2011

etiology, (ii) wound pathophysiology/progression, (iii) potential diagnostic criteria/methods and (iv) treatment interventions and strategies.

About Dynamic Reciprocity

Dynamic reciprocity is a scientific construct that describes the interactions between cells and their surrounding extracellular matrix. The term was first coined in the early 1980s by developmental cell biologists who recognized that cells and the extracelluar matrix constantly communicated with one another, and that this communication was continuously updated in response to conditions in and around the cells. This dynamic interaction was shown to be necessary in order for cells to maintain their normal structure and function, as well as for new tissue development.

Conversely, a disruption in normal dynamic reciprocity is thought to contribute to the pathophysiology of conditions ranging from certain cancers to impaired wound healing. Thus, greater understanding of the alterations of dynamic reciprocity in disease states represents an important area of scientific inquiry that could contribute to improved methods for diagnosis and treatment.

About Healthpoint Biotherapeutics

Healthpoint Biotherapeutics is a biopharmaceutical company focused on the development and commercialization of novel, cost-effective solutions for tissue repair and healing. The company's diversified research and development strategy is presently centered around therapeutic enzymes, biologics and next-generation cell- and cell-matrix based therapies for the prevention and treatment of acute, chronic and burn-related wounds. Currently marketed products include Collagenase SANTYL® Ointment and OASIS® Wound Matrix. Healthpoint Biotherapeutics is also committed to advancing the care and treatment of wounds through support of industry leading continuing education from The Wound Institute®. To learn more about this comprehensive and award winning educational resource, plea
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