Navigation Links
Drug Development Program Started Based on CAP(R) Human Cell Line
Date:3/3/2009

COLOGNE, Germany, March 3 /PRNewswire/ --

- New Platform May Provide Solutions for Many RA-Patients Around the World

Alloksys Life Sciences BV (Bunnik, The Netherlands), CEVEC Pharmaceuticals GmbH (Cologne, Germany) and PharmaCell BV (Maastricht, The Netherlands) announce the start of Theraptech, a 2.4 million Euro therapeutic protein development program subsidized under the European Trans Bio Program. The major objective of the Theraptech project is to develop a recombinant human alkaline phosphatase (rhuAP) using the novel versatile human CAP(R) cell line, which has been shown to efficiently express glycosylated proteins. The rhuAP produced in CAP(R) cells is expected to feature improved pharmacokinetic and safety profile allowing for repeated dosing of alkaline phosphatase in chronic diseases. Based on a the anti-inflammatory mechanism of action of alkaline phosphatase towards e.g. TNFa, IL-6 and IL-8, as shown in both pre-clinical and clinical studies in acute conditions, we propose it to be developed as a therapeutic protein in major chronic diseases such as Rheumatoid Arthritis. The combined expertise of the members participating in the consortium covers the entire spectrum of activities needed to drive the project from molecular biology to GMP-production and recombinant product testing in preclinical and clinical trials, pushing towards a clinical phase II compliant product within the 3-year-time frame of the project.

Commenting on this unique co-operation, PharmaCell's CEO, Maurice Horsten, commented "Combining the strengths of our companies provides us with an excellent opportunity to build on PharmaCell's motto Humanizing Medicine(R) and to push this important project forward to the benefit of many patients around the world."

Cevec's CEO Dr Rainer Lichtenberger added: "CEVEC is excited about the strong scientific and commercial prospects of the Theraptech project. rhuA
'/>"/>

SOURCE CEVEC Pharmaceuticals GmbH
Copyright©2009 PR Newswire.
All rights reserved

1

GOOD

Page: 1 2 3

Related medicine technology :

1. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
2. Promising Cystic Fibrosis Compound on Track for Development
3. Vical Reports Second Quarter 2007 Financial Results, Allowance of Pandemic Influenza IND and Other Advances in Product Development Programs
4. CuraGen Provides Update on Velafermin, Belinostat and CR011-vcMMAE Clinical Development Programs
5. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
6. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
7. New Company Starts, Bridging the Development Gap in the Discovery of Cancer Drugs
8. Quest Diagnostics Introduces ClariSure(TM) Test for Identifying Chromosome Abnormalities Associated With 85 Developmental Disorders in Children
9. WorldHeart Announces Further Milestone in Miniaturized Assist Pump Development
10. EntreMed Raises $20 Million to Support Clinical Development Program
11. Oncology Drugs Development Update - Worldwide Markets and Forecasts of Approved EGFr/HEr2 Inhibitors, Treatment Costs, Pathway Analysis, Current and Expanded Clinical Indications, and Novel Agents in Development

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/27/2009)..., SALT LAKE CITY, Nov. 27 /PRNewswire-FirstCall/...tems, Inc. (NYSE: VAR ), a premier supplier of X... will exhibit its full range of detectors at the R...29 - December 3, 2009. Varian will also be exhibi... as well as specialized cancer treatment technolog...
(Date:11/27/2009)..., CHICAGO, Nov. 27 At the upcom...nnual meeting starting Sunday, Royal Philips Elect...ge of healthcare imaging and informatics solutions...tients and care providers, by delivering meaningfu...lue, modular price points and easy upgradability. ...
(Date:11/25/2009)..., CANOGA PARK, Calif., Nov. 25 Pr...ce rankings in the American Academy of Family Phys...09 EHR User Satisfaction Survey for improving medi...ement, all critical for new ARRA Stimulus legislat...g their EMR had a positive effect in determining t...
Breaking Medicine Technology:Varian Medical Systems to Highlight the Latest Digital Detectors, X-ray Tubes and Cancer Treatment Technology at the Radiological Society of North America (RSNA) Annual Meeting in Chicago 2Philips Helps Hospitals Strike Balance Between Innovation and Value 2Philips Helps Hospitals Strike Balance Between Innovation and Value 3Philips Helps Hospitals Strike Balance Between Innovation and Value 4Praxis EMR Wins Top Rankings in 2009 AAFP EHR User Satisfaction Survey 2USHairReplacement com Provides Wealth of Knowledge to Common Hair Replacement Questions 48877 1USHairReplacement com Provides Wealth of Knowledge to Common Hair Replacement Questions 48877 2High Activity Plant Based Diamine Oxidase Enzyme Introduced by Bio Research Products 48873 1While the Dangers of Sun Exposure are Widely Understood Americans Fall Short of Adequately Protecting Themselves from the Sun 48869 1While the Dangers of Sun Exposure are Widely Understood Americans Fall Short of Adequately Protecting Themselves from the Sun 48869 2While the Dangers of Sun Exposure are Widely Understood Americans Fall Short of Adequately Protecting Themselves from the Sun 48869 3While the Dangers of Sun Exposure are Widely Understood Americans Fall Short of Adequately Protecting Themselves from the Sun 48869 4
...BUSINESS WIRE)--Apr 14, 2007 - In a late-breaker,p...pean Association,for the Study of the Liver (EASL)...interim analysis of the PROVE 1 clinical trial,wh...therapy with,the investigational hepatitis C prote...ion with pegylated interferon (peg-IFN) and,ribavi...
...SS WIRE)--Apr 16, 2007 - Antigenics Inc.,(NASDAQ: ...ted data,from a Phase 1/2 investigator-sponsored t...ne Oncophage(R) (vitespen) in,recurrent, high-grad...n Association of Neurological Surgeons (AANS; abst...ing conducted at the,Brain Tumor Research Center a...
Other Medicine Technology:Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 2Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 3Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 4Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 5Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 6Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 7Interim Results Presented at EASL from PROVE 1 Clinical Trial of,Investigational Drug Telaprevir in Patients with Genotype 1,Hepatitis C 8Data from Investigator-Sponsored Trial of Oncophage Cancer Vaccine,in Glioma Presented at American Association of Neurological,Surgeons Annual Meeting 2Data from Investigator-Sponsored Trial of Oncophage Cancer Vaccine,in Glioma Presented at American Association of Neurological,Surgeons Annual Meeting 3Data from Investigator-Sponsored Trial of Oncophage Cancer Vaccine,in Glioma Presented at American Association of Neurological,Surgeons Annual Meeting 4
(Date:11/29/2009)... "The YogaForce A-Line Athletic Mat is great....eil, M.D., author and physician best known for est...e medicine. Go to www.yogaforce.com and order t...t list. , San Francisco, ...he holidays, the YogaForce newly patented, revolut...
(Date:11/28/2009)...n believed to affect circadian rhythm, , ...search suggests that an internal body clock that g...ent of bipolar disorder in children. , The fin...akeup of 152 children with bipolar disorder, which... and 140 children without the disorder. They linke...
(Date:11/27/2009)...27 Considered a highly ...years ago, solid organ transplantation is now a li...ordinary men and women who gathered at the Winspea...ogether from medical centers around the world to c...ransplant Institute (BRTI), one of the pioneers of...
(Date:11/27/2009)... XenaCare Holdings has announced that it has becom...one of the largest nonprofit organizations dedicat...on. , Delray Beach, FL (V... (OTCBB: XCHO), a company specializing in the mark...re products, has announced today that is has becom...
(Date:11/27/2009)... Multi-purpose bilingual coloring books designed f...business community to educate - inform parents and...ty issues to Dinosuars to ABC,S and a host of othe...MO (PRWEB) November 27, 2009 -- Today’s chil...eep them busy any hour of the day, but one of the ...
Breaking Medicine News(10 mins):Health News:The YogaForce A-Line Mat Provides The Perfect Solution For Fitness Needs 2Health News:The YogaForce A-Line Mat Provides The Perfect Solution For Fitness Needs 3Health News:Bipolar Disorder May Be Tied to Body Clock 2Health News:Organ Transplant Pioneers Celebrate Baylor Regional Transplant Institute's 25th Anniversary 2Health News:Organ Transplant Pioneers Celebrate Baylor Regional Transplant Institute's 25th Anniversary 3Health News:XenaCare Holdings Announces National Sponsorship of the Arthritis Foundation 2Health News:XenaCare Holdings Announces National Sponsorship of the Arthritis Foundation 3Health News:XenaCare Holdings Announces National Sponsorship of the Arthritis Foundation 4Health News:Really Big Coloring Books Debuts Bi-Lingual Spanish-English Line of Custom and Imprintable Coloring Books 2
..., Newly Installed System at Apollo Hospital Treats...UNNYVALE, Calif., April 3 Accuray Incorporated (N...adiosurgery, announced today that the first patien...i, India, treated six patients in its first week o...
...Prospect stems from discovery of mutation affectin...thDay News) -- Gene mutations that cause infertili...rol pill, American and Iranian researchers say. , ...therapies that replace the gene or the protein. Bu...
..., Physicians can dramatically reduce the radiatio...T angiography in a "triple rule-out" protocol by s...a study performed at Thomas Jefferson University H...95 patients who were evaluated with tube current m...
..., Hyland Software ,s award-winning document mana...EMR integration, administrative, revenue cycle man...3 It,s no secret. Getting the right people all of...et have the tools to operate this efficiently. The...
..., KINGSTON, R.I. March 27, 2009 The U.S. Patent ...Rhode Island pharmacy professor,s proposal to use ...ions of anti-rejection drugs in patients that unde...such as cyclosporine, and mycophenolic acid, which...
..., 1450, the leading distr...re announces the launch of EHRtv, a wide-ranging v... with EHR Scope and EHRConsultant.com, EHRtv now p...- 1450, the world,s leading distributor of Dragon&...
Other Medicine News:Health News:First Patients Treated in India Using CyberKnife Radiosurgery 2Health News:First Patients Treated in India Using CyberKnife Radiosurgery 3Health News:First Patients Treated in India Using CyberKnife Radiosurgery 4Health News:Genetic Finding May Lead to Male Contraceptive 2Health News:Radiation dose can be reduced for 'triple rule-out' coronary CT angiography 2Health News:American Hospital Association Expands OnBase Endorsement to All Hospital Departments 2Health News:American Hospital Association Expands OnBase Endorsement to All Hospital Departments 3Health News:American Hospital Association Expands OnBase Endorsement to All Hospital Departments 4Health News:Patent pending for pain-free method of monitoring drug levels in transplant patients 2Health News:1450, Inc Launches EHRtv 2
... come with five legs for extra stability. Adjustab...el 6"). 2" ball bearing swivel hard rubber castors...ry, available in black vinyl as standard, other co...red, padded, upholstered backrest, with vertical a...
Lacrimal Cannula, 19 g / 23 g. Straight
Anterior Chamber Needle, 21 g
Nucleus Hydrodissection Cannula, 25 g
Medicine Products: