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Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies
Date:11/30/2011

ular markets 153

Markets for cardiovascular devices 153

Marketing of innovative cardiovascular drug delivery devices 153

Direct to consumer advertising of DES 154

Future trends in the integration of drug delivery with therapeutics 154

Future prospects of cardiovascular drug delivery 154

7. Companies involved in Cardiovascular Drug Delivery 155

Profiles of companies 155

Collaborations 241

8. References 245

List of Tables

Table 1 1: Landmarks in the historical evolution of cardiovascular drug delivery 13

Table 1 2: Gene polymorphisms that alter cardiovascular response to drugs 18

Table 2 1: Routes of drug delivery used for treatment of cardiovascular disorders 25

Table 2 2: Formulations for drug delivery to the cardiovascular system 27

Table 2 3: Improved methods of systemic drug delivery of cardiovascular drugs 32

Table 2 4: Targeted delivery of therapeutic substances to the cardiovascular system 35

Table 2 5: Classification of devices for drug delivery to the cardiovascular system 36

Table 2 6: Various methods of delivery of therapeutic agents for hypertension 41

Table 2 7: Marketed controlled/ extended release preparation for hypertension 43

Table 2 8: Drug delivery in ischemic heart disease 45

Table 2 9: Methods of delivery of nitrate therapy in angina pectoris 49

Table 2 10: Drug delivery for peripheral arterial disorders 54

Table 3 1: Clinical trials of cell therapy in cardiovascular disease 73

Table 4 1: Cardiovascular disorders for which gene therapy is being considered. 79

Table 4 2: Catheter-based systems for vector delivery to the cardiovascular system 80

Table 4 3: Potential applications of antisense in cardiovascular disorders 99

Table 4 4: Companies involved in gene therapy of cardiovascular diseases 104

Table 5 1: Treatment of restenosis 108

Table
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