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Drug Delivery in Central Nervous System Diseases - Technologies, Markets and Companies
Date:11/30/2011

p>Role of DES in cases of bare-metal in-stent restenosis 134

DES versus balloon catheter coated with paclitaxel 135

DES versus intracoronary radiation therapy for recurrent stenosis 135

Cost-effectiveness of DES 136

Safety issues of DES 136

Adverse reactions to DES 136

Endothelial vascular dysfunction due to sirolismus 137

Risk of clotting with DES 137

Clopidogrel use and long-term outcomes of patients receiving DES 139

Prasugrel as antiplatelet agent 139

Effect of blood clot on release of drug from DES 139

Use of magnetized cell lining to prevent clotting of DES 140

Long-term safety studies of DES 140

Regulatory issues of DES 141

Future prospects for treatment of restenosis by DES 142

Future role of DES in management of cardiovascular diseases 142

Stent cost and marketing strategies 143

Improvements in stent technology 143

Bioabsorbale stent 144

DES vs drug-eluting balloons 144

6. Markets for Cardiovascular Drug Delivery 145

Introduction 145

Epidemiology of cardiovascular disease 145

Cost of care of cardiovascular disorders 146

Cardiovascular markets according to important diseases 147

Antithrombotics 147

Anticholesterol agents 147

Antihypertensive agents 148

Drugs for congestive heart failure 148

Markets for innovative technologies for cardiovascular disorders 148

Markets for cell therapy of cardiovascular disorders 148

Markets for gene therapy of cardiovascular disorders 149

Markets for drug-eluting stents 149

Major players in DES market 149

Impact of safety issues on future markets for DES 149

DES market in Asia 150

Patenting and legal issues of DES 151

The financial impact of DES on cardiovascular markets 151

Unmet needs for cardiovascular drug delivery 152

Role of DDS in developing cardiovasc
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