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Drug Combo Could Lower Diabetes Complications and Costs
Date:4/27/2008

y, reproductive years has risen dramatically.

This study, by researchers at Kaiser Permanente in Southern California, found the prevalence of pre-existing type 1 or type 2 diabetes among pregnant women doubled, from less than one (0.81) out of 100 pregnancies in 1999 to close to two (1.82) out of 100 pregnancies in 2005. During the same period, the prevalence of gestational diabetes (diabetes that develops during pregnancy and then disappears after the baby is born) remained relatively stable.

Both pre-existing diabetes and gestational diabetes have health implications for mother and child that extend far beyond pregnancy. However, for women with pre-existing diabetes, maternal hyperglycemia that exists prior to pregnancy and continues into the first 8 weeks of gestation exposes the fetus to an increased risk of miscarriage and birth defects. Additionally, the earlier onset and longer duration of maternal diabetes also suggests the women may develop diabetes-related complications at an earlier age, the researchers concluded.

Dr. Jean Lawrence, the lead author on this study, suggests that "interventions that focus on reducing overweight and obesity can help decrease the number of women who have diabetes during their reproductive years. Given the increasing prevalence of diabetes in childbearing-age women, the awareness that preconception care reduces maternal and infant complications for women with diabetes as well as the availability of these services becomes increasingly important."

Diabetes Care, published by the American Diabetes Association, is the leading peer-reviewed journal of clinical research into the nation's fifth leading cause of death by disease. Diabetes also is a leading cause of heart disease and stroke, as well as the leading cause of adult blindness, kidney failure, and non-traumatic amputations. For more information about diabetes, visit the American Diabetes Association Web site

SOURCE American Diabetes Association
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