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Drug Combination Highly Effective for Newly Diagnosed Myeloma Patients, Study Finds
Date:12/12/2011

defective proteins. Because myeloma cells develop from antibody-producing white blood cells, they are "protein factories." Blocking their efforts to get rid of dysfunctional proteins can lead to cell death.

The Multiple Myeloma Research Consortium, Onyx Pharmaceuticals Inc., Celgene Corp. and the University of Michigan funded the study.

Additional authors include Dominik Dytfeld, Tara B. Anderson, Brian Nordgren, Daniel Lebovic, Kent Griffith, K Detweiler-Short, Terri Jobkar, Diane Durecki, Ammar Al-Zoubi, Daniel Couriel, and Melissa Mietzel from the University of Michigan; Sundar Jagannath from Mt. Sinai Medical Center, New York; David H. Vesole from Hackensack University Medical Center; Keith Stockerl-Goldstein and Ravi Vij from Washington University School of Medicine; Robert Ott and Sandra Wear from the Multiple Myeloma Research Consortium; Mohamad Hussain from Celgene Corp.; and Homa Yeganegi from Onyx Pharmaceuticals Inc.

Presentation: 53nd American Society of Hematology Annual Meeting and Exposition, Dec. 10-13, 2010, Orlando, Fla. 631 - Final Results of a Frontline Phase 1/2 Study of Carfilzomib, Lenalidomide, and Low-Dose Dexamethasone (CRd) in Multiple Myeloma (MM). Monday, December 12, 2011: 2:45 PM, Ballroom 20D (San Diego Convention Center).


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SOURCE University of Chicago Medical Center
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