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Dramatic JUPITER Findings Fail to Sway Prescribing Behavior, Poll Shows
Date:11/25/2008

rgery, or cardiovascular death was 44%.

MedPage Today poll participants registered mixed views as to the best preventive cardiovascular strategy, with most alternating between lifestyle changes and drug therapy.

Among the majority of those voting against lifelong drug therapy was one M.D., who commented, "The American people want the magic bullet that will allow them to continue their unhealthful lifestyles when they should lower their BMI to between 25 and 22, restrict caloric intake and [increase] exercise. What are the costs? Low."

The same physician lamented that funding more sound research into the biological origins of inflammation with the potential of devising activity and dietary strategies to prevent type II diabetes and cardiovascular disease is neither commercially viable for pharmaceutical corporations nor sufficiently funded by NIH and is thus "not likely to happen."

A second M.D., wary of statins, objected to placing people on medications who ostensibly don't need them. "Statins have side effects such as myopathy and ED with decreased libido in men and women," he observed. "Recently they have been associated with cognitive impairment and possible early development of Alzheimer's."

A third agreed, saying, "The side effects and potential for serious problems [with statins] outweighs the benefit. Muscle weakness is common, and often does not go away until months after stopping. Don't do it."

Statins, like any other drug, have side effects, "but research and time have shown their efficacy in lowering cardiovascular events," countered a general practitioner. Speaking for the minority of those who favor statins among the healthy elderly, he commented, "As family physicians, we are intended to [practice] preventive medicine." The combination of LDL <130 and CRP >2 should be "the golden key" for receiving treatment.


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