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Discovery Labs Releases New AFECTAIR™ Performance Data Presented at the American Association for Respiratory Care Annual Meeting
Date:11/8/2011

WARRINGTON, Pa., Nov. 8, 2011 /PRNewswire/ -- Discovery Laboratories, Inc. (Nasdaq: DSCO) today announced that new data supporting AFECTAIR™, the Company's newest product candidate, was presented at the American Association for Respiratory Care (AARC) Congress 2011, internationally recognized as the most relevant medical meeting dedicated to advancing the science and practice of respiratory care. AFECTAIR has been developed by Discovery Labs to simplify the delivery of inhaled therapies for critical care patients requiring ventilatory support. Data from three in-vitro performance studies were presented that assessed the utility of AFECTAIR compared with current standard of care (SoC) ventilatory circuit componentry. Study investigators concluded that use of AFECTAIR:

  • Supported a statistically significant 6 to 14 fold increase (p < 0.05) in the delivery of aerosolized albuterol when compared with the SoC delivery system, suggesting that potential clinical use of AFECTAIR may result in increased delivery of aerosolized medication to patients receiving positive pressure ventilatory support;

  • Resulted in particle size distribution (PSD) of albuterol that spanned the entire respirable range, while the SoC delivery system resulted in PSD at or below the lower end of the respirable range, suggesting that potential clinical use of AFECTAIR may result in increased retention of aerosolized medication in the lung;

  • Did not increase resistance in the ventilator circuitry, suggesting that AFECTAIR may be a comparably safe alternative to SoC devices in ventilator circuits.

"AFECTAIR provides a simplified and more intuitive solution for the delivery of inhaled therapies to patients requiring ventilatory support. Our plan to evaluate the utility of AFECTAIR includes a seri
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SOURCE Discovery Laboratories, Inc.
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